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1,274 results for “Disease Model”

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geo24/100

An integrated organoid omics map extends modeling potential of kidney disease

GEO Series GSE213972. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2023View details →
geo24/100

The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of Amyotrophic Lateral Sclerosis

GEO Series GSE281064. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modelling (passages)

GEO Series GSE287566. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo24/100

Tau accumulation induces microglial state alterations in Alzheimer’s disease model mice (snRNA-seq, part 1)

GEO Series GSE270385. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2024View details →
geo24/100

A platform for generation of chamber specific cardiac tissues and disease modelling

GEO Series GSE122661. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2018View details →
geo24/100

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [ChIP-Seq]

GEO Series GSE85628. Homo sapiens. 75 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2016View details →
geo24/100

Stem cell-derived human liver organoids to model the progression of inflammatory and fibrotic injury in non-alcoholic fatty liver disease

GEO Series GSE207889. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Microglia - astrocyte cross-talk in the amyloid plaque niche of an Alzheimer’s disease mouse model as revealed by spatial transcriptomics (CosMx)

GEO Series GSE263791. Mus musculus. 2 samples. Type: Other.

openGEO-OpenApr 2024View details →
geo24/100

Transcriptome profiling in knock-in mouse models of Huntington's disease [Striatum_miRNA]

GEO Series GSE65773. Mus musculus. 208 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenFeb 2016View details →
geo24/100

Aging, microglia and cytoskeletal regulation are key factors in the pathological evolution of the APP23 mouse model for Alzheimer’s disease

GEO Series GSE80465. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2016View details →
geo24/100

Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling [scRNA-seq]

GEO Series GSE318347. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2026View details →
geo24/100

Mutant huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease [Ribo-seq]

GEO Series GSE146674. Mus musculus. 9 samples. Type: Other.

openGEO-OpenJul 2020View details →
geo24/100

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq]

GEO Series GSE85623. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2016View details →
geo24/100

Modeling SMAD2 mutations in iPSCs provides insights into cardiovascular disease pathogenesis. [ATAC-Seq]

GEO Series GSE278726. Homo sapiens. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo24/100

Functional characterization of a single nucleotide polymorphism associated with Alzheimer’s Disease in a hiPSC-based neuron model.

GEO Series GSE239367. Homo sapiens. 100 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo24/100

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model [snRNAseq]

GEO Series GSE254104. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

Maximizing HLC production in bioreactors: unveiling the role of oxygen control for enhanced yield and PH1 disease modelling

GEO Series GSE267210. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo24/100

Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [Xenon scRNAseq Myeloid]

GEO Series GSE274764. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo24/100

Phenotypic and genomic analysis of multiple myeloma minimal residual disease clonal plasma cells: a new model to understand chemoresistance

GEO Series GSE70399. Homo sapiens. 30 samples. Type: Genome variation profiling by SNP array; Expression profiling by array.

openGEO-OpenJan 2016View details →
geo24/100

Effect of global Caspase-1 (Casp1) knockout (KO) on kidney gene expression in an orthologous mouse model of polycystic kidney disease (PKD)

GEO Series GSE207957. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2022View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record