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2,445 results for “Genetics: population”
Temporal population structure, a genetic dating method for ancient Eurasian genomes from the past 10,000 years
<p>Radiocarbon dating is the gold standard in archeology to estimate the age of skeletons, a key to studying their origins. Many published ancient genomes lack reliable and direct dates, which results in obscure and contradictory reports. Here, we developed the Temporal Population Structure (TPS), the first DNA-based dating method for ancient genomes ranging from the Late Mesolithic to modern-days, and applied it to 3,591 ancient and 1,307 modern Eurasians. We show that TPS predictions align with their known dates and correctly account for kin relationships. TPS dating of poorly dated Eurasian samples resolved conflicting reports in the literature, as illustrated by one test case. We demonstrated how TPS improved the ability to study phenotypic traits over time.</p>
Data for: Genetic control of grain amino acid composition in a UK soft wheat mapping population
<p>Wheat is a major source of nutrients for populations across the globe, but the amino acid composition of wheat grain does not provide optimal nutrition. The nutritional value of wheat grain is limited by low concentrations of lysine (the most limiting essential amino acid) and high concentrations of free asparagine (precursor to the processing contaminant acrylamide). There are currently few available solutions for asparagine reduction and lysine biofortification through breeding. In this study, we investigated the genetic architecture controlling grain-free amino acid composition and its relationship to other traits in a Robigus × Claire doubled haploid population. Multivariate analysis of amino acids and other traits showed that the two groups are largely independent of one another, with the largest effect on amino acids being from the environment. Linkage analysis of the population allowed the identification of QTL controlling free amino acids and other traits, and this was compared against genomic prediction methods. Following the identification of a QTL controlling free lysine content, wheat pangenome resources facilitated analysis of candidate genes in this region of the genome. These findings can be used to select appropriate strategies for lysine biofortification and free asparagine reduction in wheat breeding programmes.</p>
Figure 5 in Expanding Population Edge Craniometrics and Genetics Provide Insights into Dispersal of Commensal Rats through Nusa Tenggara, Indonesia
Figure 5. Genetic clustering based on allele frequencies of 12 microsatellite loci genotyped for Rattus rattus Complex samples from MSEA and extralimital distribution in Indonesia (IDN). (A) PCoA, (B) STRUCTURE barplot.
Figure 4. Haplotype network for Rattus rattus Complex II in Expanding Population Edge Craniometrics and Genetics Provide Insights into Dispersal of Commensal Rats through Nusa Tenggara, Indonesia
Figure 4. Haplotype network for Rattus rattus Complex II. The Nusa Tenggara samples are illustrated on the right of the network.
Figure 1 in Expanding Population Edge Craniometrics and Genetics Provide Insights into Dispersal of Commensal Rats through Nusa Tenggara, Indonesia
Figure 1. Cranial measurements taken for each specimen: supraoccipital height (BH), basal length (BLL), basilar length (BRL), length of the bullae (BULL), condylobasal length (CBL), condylobasilar length (CBRL), minimum corpus length (CL), length of the diastema (DA), foramen magnum height (FMH), foramen magnum width (FMW), length of the incisive foramina (FOR), length of the face (GES), length of the braincase (HKL), thickness of the incisor (ID), interorbital breadth (IOB), mandibular diastema length (LAL), thickness lower incisor (LID), mandibular alveoli length (MAL), mandibular toothrow length (crown) (MCL),mandibular depth (MD), maximum mandibular height (MDL), mandibular depth at M1 (MID), mandibular length (ML), nasal length (NAS), nasal breadth (NASB), occipital breadth (OCB), occipital length (OCN), supraoccipital width at the occipital condyles (OCW), length of the upper molar row (alveoli) (OZRA), length of the upper molar row (crown) (OZRK), palatal length (PL), palatine breadth (PRL), rostral breadth (RB), rostral height (RH), breadth of braincase (SKB), height of braincase with bullae (SKH), zygomatic plate (ZP), zygomatic breadth (ZYG).
Figure 3. Haplotype networks for Rattus exulans, R in Expanding Population Edge Craniometrics and Genetics Provide Insights into Dispersal of Commensal Rats through Nusa Tenggara, Indonesia
Figure 3. Haplotype networks for Rattus exulans, R. argentiventer, and Rattus rattus Complex LIV. Sunda refers to the islands of Borneo, Java, and Sumatra; the Indonesian sample (brown) lacks further collection information.
Figure 6 in Expanding Population Edge Craniometrics and Genetics Provide Insights into Dispersal of Commensal Rats through Nusa Tenggara, Indonesia
Figure 6. Summary of likely movements of the three commensal rodents through the Nusa Tenggara island chain. Rat illustrations redrawn and adapted from R. Budden, location of RS3 Dong Song drums from Calo (2014).
Genetic differentiation following recent domestication events: A study of farmed Nile tilapia (Oreochromis niloticus) populations
<p>SNP array data from our research article. It contains the SNP markers in common across the different Nile tilapia (Oreochromis niloticus) populations assessed in the study</p>
Data from: Additive genetic and environmental variation interact to shape the dynamics of seasonal migration in a wild bird population
<p><span>Dissecting joint micro-evolutionary and plastic responses to environmental perturbations requires quantifying interacting components of genetic and environmental variation underlying expression of key traits. This ambition is particularly challenging for phenotypically discrete traits where multiscale decompositions are required to reveal non-linear transformations of underlying genetic and environmental variation into phenotypic variation, and when effects must be estimated from incomplete field observations. We devised a joint multistate capture-recapture and quantitative genetic animal model and fitted this model to full-annual-cycle resighting data from partially-migratory European shags (<em>Gulosus</em> <em>aristotelis</em>) to estimate key components of genetic, environmental and phenotypic variance in the ecologically critical discrete trait of seasonal migration versus residence. We demonstrate non-negligible additive genetic variance in latent liability for migration, resulting in detectable micro-evolutionary responses following two episodes of strong survival selection. Further, liability-scale additive genetic effects interacted with substantial permanent individual and temporary environmental effects to generate complex non-additive effects on expressed phenotypes, causing substantial intrinsic gene-by-environment interaction variance on the phenotypic scale. Our analyses therefore reveal how temporal dynamics of partial seasonal migration arise from combinations of instantaneous micro-evolution and within-individual phenotypic consistency, and highlight how intrinsic phenotypic plasticity could expose genetic variation underlying discrete traits to complex forms of selection.</span></p>
Figure 5 Nav kdr 1016 and 1534 in Genetic study in Aedes (Stegomyia) aegypti (Linnaeus, 1762) from Londrina (Paraná State, Brazil): an approach to population structure and pyrethroid resistance
Figure 5 Nav kdr 1016 and 1534 site allele frequencies in UEL. Collection site locations were distributed in the three regions of the campus.
Figure 4 in Genetic study in Aedes (Stegomyia) aegypti (Linnaeus, 1762) from Londrina (Paraná State, Brazil): an approach to population structure and pyrethroid resistance
Figure 4 Allele frequencies of Nav kdr 1016 and 1534 genotyping distributed in the five different regions of Londrina.
Figure 3 in Genetic study in Aedes (Stegomyia) aegypti (Linnaeus, 1762) from Londrina (Paraná State, Brazil): an approach to population structure and pyrethroid resistance
Figure 3 Haplotypic network obtained through specimens collected in UEL. The circles are proportional to the number of specimens observed in each haplotype.
Figure 2 in Genetic study in Aedes (Stegomyia) aegypti (Linnaeus, 1762) from Londrina (Paraná State, Brazil): an approach to population structure and pyrethroid resistance
Figure 2 Haplotype network observed in five regions of Londrina. The circles are proportional to the number of specimens observed in each haplotype. The haplotypes observed are in bold. The numbers represent nucleotide change positions.
Figure 1 in Genetic study in Aedes (Stegomyia) aegypti (Linnaeus, 1762) from Londrina (Paraná State, Brazil): an approach to population structure and pyrethroid resistance
Figure 1 Collection sites in Londrina. The red line is a boundary between the five regions of the city. The yellow ones represent the streets and avenues of the city. Only the urban area was evaluated in the study.
Data and codes from "How does dispersal shape the genetic structure of animal populations in European cities? A simulation approach"
<p>Codes and data used for "Savary et al. How does dispersal shape the genetic structure of animal populations in European cities? A simulation approach".</p> <p> </p>
All data for the preprint Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a significant decrease of human exposure to the disease
<p>Data set for the paper titled "Population genetics of <em>Glossina palpalis gambiensis</em> in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a significant decrease of human exposure to the disease"</p>
Population genomic evidence that stream networks structure genetic diversity in the narrowly endemic patch-nosed salamander (Urspelerpes brucei)
<p>Described in 2009, the Patch-nosed Salamander (<em>Urspelerpes brucei</em>) is a miniature species of lungless salamander with a geographic range of only ~45 km<sup>2</sup>. This species is endemic to the foothills of the Appalachian Mountains in extreme northeastern Georgia and northwestern South Carolina. The Tugaloo River—a waterway of some 50 m in width that forms the political boundary between the two states—bisects the tiny range of <em>U. brucei</em> and likely acts as a barrier to gene flow. Using RADcap data and a suite of complementary population genomic analyses, we evaluated the role that this river and its tributaries may play in enabling and/or interrupting gene flow among populations of <em>U. brucei</em>, and we investigated patterns of within-population and between-population genetic variation. Our results revealed a general pattern of isolation-by-stream distance and indicated that a population separated by the Tugaloo River is moderately more differentiated than what is explainable by stream distance alone. Unique in both its physiography and geologic history, this region in which <em>U. brucei</em> lives also harbors more than a dozen other species of lungless salamanders. Therefore, the genetic patterns that we have elucidated may have larger implications for differentiation among populations of other species with similar dispersal abilities.</p>
figure 1 in Spatial genetic structure in the Eurasian otter (Lutra lutra) meta-population from its core range in Italy
figure 1 The area surveyed for collection of otter samples (40° 40' N, 39° 37' N). Red spots indicate the location of the collected samples. The blue lines highlight the main rivers (order 1) and their tributaries (order 2, 3 and 4 according to waterway hierarchy). The continuous red lines represent regional boundaries. In the inset, the current otter distribution (inferred from Balestrieri et al., 2016, modified) is reported in orange and the study area is defined by the black bold square.
figure 4 in Spatial genetic structure in the Eurasian otter (Lutra lutra) meta-population from its core range in Italy
figure 4 Principal Component Analysis (pca) performed on microsatellite genotypes (dots). Circles show the well-defined spatial groups. A) pca according to the belonging of genotypes to the six river basins: the Cilento basin (green dots); the Agri basin (pink dots); the Sinni basin (blue dots); the Lao basin (red dots); the Basento basin (orange dots); the Abatemarco basin (violet dots); black dots indicate the samples outside of the main river basins. Dashed line indicates geographically contiguous but genetically different genotypes. B) pca according to clusters inferred by STRUCTURE: genotypes assigned unambiguously to K2 (green dots), to K3 (yellow dots), to K5 (violet dots). Grey dots represent samples with mixed genotypes assignable to K1 and K4.
figure 3 in Spatial genetic structure in the Eurasian otter (Lutra lutra) meta-population from its core range in Italy
figure 3 Genetic structure and distribution of the Italian otter genotypes in the study area. A) Estimated population structure based on the analysis of 11 microsatellite loci according to STRUCTURE (K = 5). Each bar represents a sample analysed. B) Geographic visualisation of genotypes in the study area performed using QGIS 3.4.1 software with base layers acquired from http://www.pnc.miniambiente. it/. Each circle represents a sample analysed. The colours indicate the percentage of assignment of an individual to each cluster: in blue, K1; in green, K2; in orange, K3; in red, K4; in violet, K5. The bold blue lines highlight the main rivers, while the tiny blue lines show all other waterways.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.