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322
datasets available to search
ShareScore release 0.9.0
Dataset results
322 results for “endothelial dysfunction”
miR548ai antagonism attenuates exosome-induced endothelial cell dysfunction
GEO Series GSE185784. Homo sapiens. 5 samples. Type: Expression profiling by array.
miRNA species as systemic mediators of environmentally persistent free radical-induced endothelial dysfunction [C57 mice]
GEO Series GSE286172. Mus musculus. 24 samples. Type: Other.
Endothelial dysfunction in NR2F2-silenced cells - human lung microvascular endothelial cells model
GEO Series GSE188467. Homo sapiens. 10 samples. Type: Expression profiling by array.
Endothelial cells drive organ fibrosis and dysfunction by inducing the transcription factor SOX9 (ATAC-Seq)
GEO Series GSE252081. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Endothelial dysfunction in NR2F2-silenced cells - human coronary artery endothelial cells model
GEO Series GSE188466. Homo sapiens. 10 samples. Type: Expression profiling by array.
Endothelial cells drive organ fibrosis and dysfunction by inducing the transcription factor SOX9 (CUTNTAG)
GEO Series GSE252082. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Stress-induced RNA–chromatin interactions promote endothelial dysfunction (Hi-C)
GEO Series GSE135354. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Nutritional targeting of the gut microbiota: a novel approach in the management of endothelial dysfunction
GEO Series GSE87603. Mus musculus. 4 samples. Type: Expression profiling by array.
Stress-induced RNA–chromatin interactions promote endothelial dysfunction (iMARGI replicate 2)
GEO Series GSE156339. Homo sapiens. 2 samples. Type: Other.
Anti-cancer therapy induces endothelial dysfunction in the human microcirculation that is prevented by VEGF-B overexpression
GEO Series GSE261326. Homo sapiens. 25 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to the article "Endothelial Dysfunction in Patients with Severe Mitral Regurgitation"
<p>This record contains raw data related to the article "Endothelial Dysfunction in Patients with Severe Mitral Regurgitation"</p> <p> </p> <p><strong>Abstract</strong></p> <p>Mitral valve prolapse (MVP) is the most common cause of severe mitral regurgitation. It has been reported that MVP patients—candidates for mitral valve repair (MVRep)—showed an alteration in the antioxidant defense systems as well as in the L-arginine metabolic pathway. In this study, we investigate if oxidative stress and endothelial dysfunction are an MVP consequence or driving factors. Forty-five patients undergoing MVRep were evaluated before and 6 months post surgery and compared to 29 controls. Oxidized (GSSG) and reduced (GSH) forms of glutathione, and L-arginine metabolic pathway were analyzed using liquid chromatography-tandem mass spectrometry methods while osteoprotegerin (OPG) through the ELISA kit and circulating endothelial microparticles (EMP) by flow cytometry. Six-month post surgery, in MVP patients, the GSSG/GSH ratio decreased while symmetric and asymmetric dimethylarginines levels remained comparable to the baseline. Conversely, OPG levels significantly increased when compared to their baseline. Finally, pre-MVRep EMP levels were significantly higher in patients than in controls and did not change post surgery. Overall, these results highlight that MVRep completely restores the increased oxidative stress levels, as evidenced in MVP patients. Conversely, no amelioration of endothelial dysfunction was evidenced after surgery. Thus, therapies aimed to restore a proper endothelial function before and after surgical repair could benefit MVP patients.</p>
CompREhensive Diagnostic Assessment of Coronary Endothelial Function Impairment and Vasospasm With CoNtinuous ThErmodilution in Patients With Suspected Coronary Microvascular and Vasomotor Dysfunction
ClinicalTrials.gov study NCT07337005. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Effect of Febuxostat on Endothelial Dysfunction in Hemodialysis Patients.
ClinicalTrials.gov study NCT02866214. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Effect of Pravastatin on Endothelial Dysfunction Following a Single High Fat Meal
ClinicalTrials.gov study NCT00005117. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome
ClinicalTrials.gov study NCT06723002. IPD Sharing: NO. Countries: 0. Publications: 0.
Syndrome X and Endothelial Dysfunction
ClinicalTrials.gov study NCT00190086. IPD Sharing: Not stated. Countries: 0. Publications: 0.
CHIP in Endothelial Dysfunction Associated With HEpEF
ClinicalTrials.gov study NCT05828888. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Exploratory Trial to Evaluate Premature Endothelial Dysfunction in Early Rheumatoid Arthritis(RA)Compared to Patients With Established RA, and Normal Subjects
ClinicalTrials.gov study NCT01499732. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Role of Endothelial Dysfunction in Adult Polycystic Kidney Disease
ClinicalTrials.gov study NCT04023214. IPD Sharing: NO. Countries: 0. Publications: 0.
Pronostic Value of Endothelial Dysfunction in Heart Failure
ClinicalTrials.gov study NCT02859636. IPD Sharing: Not stated. Countries: 0. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.