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1,049 results for “robustness”
data from Robust multisensory deviance detection in the mouse parietal associative area
<p>This is all the data analysed in the paper "Robust multisensory deviance detection in the mouse parietal associative area." It goes along with the code in https://zenodo.org/record/8189912</p>
Dataset to publication: ''Magnetstein: An open source tool for quantitative NMR mixture analysis robust to low resolution, distorted lineshapes and peak shifts''
<p>MANIQ (plugin for Mnova 14.3.1 software (Mestrelab Research, S. L., Spain)) and ACD/TP (Targeted Profiling tool for ACD/Spectrus 2020.1.1 (Advanced Chemistry Development, Inc., ACD/Labs Ontario, Toronto, ON, Canada)) project files and raw experimental NMR data to:</p> <table> <caption>Experiments obtained to Magnetstein with optimized parameters, Magnetstein with default parameters, ACD/TP and MANIQ.</caption> <tbody> <tr> <td>Exp. no.</td> <td>Problem</td> <td>Ingredients</td> </tr> <tr> <td>1</td> <td>large intensity differences<br> between peaks</td> <td>α-pinene<br> benzyl benzoate<br> (in CDCl<sub>3</sub>)</td> </tr> <tr> <td>2</td> <td>peak overlap<br> & contamination (extra peaks)</td> <td>imonene<br> α-pinene<br> (in CDCl<sub>3</sub>)</td> </tr> <tr> <td>3</td> <td>low resolution (43 MHz<br> benchtop NMR spectrometer)</td> <td>benzyl benzoate<br> isopropyl myristate<br> limonene<br> pinene</td> </tr> <tr> <td>4</td> <td>lineshape distortion<br> (shim z1 & z2)</td> <td>actate<br> alanine<br> creatine<br> creatinine<br> choline chloride<br> (in D<sub>2</sub>O)</td> </tr> <tr> <td>5</td> <td>peak position<br> mismatch<br> between library<br> and mixture<br> (different<br> temperatures)</td> <td>actate<br> alanine<br> creatine<br> creatinine<br> choline chloride<br> (in D<sub>2</sub>O)</td> </tr> <tr> <td>6</td> <td>test sample</td> <td>α-pinene<br> benzyl benzoate<br> (in CDCl<sub>3</sub>)</td> </tr> <tr> <td>7</td> <td>large intensity<br> differences<br> & peak overlap</td> <td><br> benzyl benzoate<br> m-anisaldehyde<br> (in CDCl<sub>3</sub>)</td> </tr> <tr> <td>8</td> <td><br> peak overlap &<br> different solvents<br> for single<br> ingredients (in CDCl<sub>3</sub>)<br> and mixture (DMSO-d<sub>6</sub>)</td> <td>benzyl benzoate<br> m-anisaldehyde</td> </tr> <tr> <td>9</td> <td>ineshape<br> distortion<br> (shim z2)</td> <td>actate<br> alanine<br> creatine<br> creatinine<br> choline chloride<br> (in D<sub>2</sub>O)</td> </tr> </tbody> </table> <p> </p>
Data from: Robustness of Felsenstein's versus transfer bootstrap supports with respect to taxon sampling
<p><span>The bootstrap method is based on resampling sequence alignments and re-estimating trees. Felsenstein's bootstrap proportions (FBP) is the most common approach to assess the reliability and robustness of sequence-based phylogenies. However, when increasing taxon sampling (i.e., the number of sequences) to hundreds or thousands of taxa, FBP tends to return low supports for deep branches. The Transfer Bootstrap Expectation (TBE) has been recently suggested as an alternative to FBP. TBE is measured using a continuous transfer index in [0,1] for each bootstrap tree, instead of the binary {0,1} index used in FBP to measure the presence/absence of the branch of interest. TBE has been shown to yield higher and more informative supports, while inducing a very low number of falsely supported branches.</span> <span>Nonetheless, it has been argued that TBE must be used with care due to sampling issues, especially in datasets with high number of closely related taxa. In this study, we conduct multiple experiments by varying taxon sampling and comparing FBP and TBE support values on different phylogenetic depth, using empirical datasets. Our results show that the main critique of TBE stands in extreme cases with shallow branches and highly unbalanced sampling among clades, but that TBE is still robust in most cases, while FBP is inescapably negatively impacted by high taxon sampling. We suggest guidelines and good practices in TBE (and FBP) computing and interpretation.</span></p>
Dataset: Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models
<p><em>KCNMA1</em> encodes the voltage- and calcium-activated K<sup>+</sup> (BK) channel, which regulates suprachiasmatic nucleus (SCN) neuronal firing and circadian behavioral rhythms. Gain-of-function (GOF) and loss-of-function (LOF) alterations in BK channel activity disrupt circadian behavior, but the effect of human disease-associated <em>KCNMA1</em> channelopathy variants has not been studied on clock function. Here, we assess circadian behavior in two GOF and one LOF mouse lines. Heterozygous <em>Kcnma1</em><sup>N999S/WT</sup> and homozygous <em>Kcnma1</em><sup>D434G/D434G</sup> mice are validated as GOF models of paroxysmal dyskinesia (PNKD3), but whether circadian rhythm is affected in this hypokinetic locomotor disorder is unknown. Conversely, homozygous LOF <em>Kcnma1</em><sup>H444Q/H444Q </sup>mice do not demonstrate PNKD3. We assessed circadian behavior by locomotor wheel running activity. All three mouse models were rhythmic, but <em>Kcnma1</em><sup>N999S/WT</sup> and <em>Kcnma1</em><sup>D434G/D434G</sup> showed reduced circadian amplitude and decreased wheel activity, corroborating prior studies focused on acute motor coordination. In addition, <em>Kcnma1</em><sup>D434G/D434G</sup> mice had a small decrease in period. However, the phase-shifting sensitivity for both GOF mouse lines was abnormal. Both <em>Kcnma1</em><sup>N999S/WT</sup> and <em>Kcnma1</em><sup>D434G/D434G</sup> mice displayed increased responses to light pulses and took fewer days to re-entrain to a new light:dark cycle. In contrast, the LOF <em>Kcnma1</em><sup>H444Q/H444Q </sup>mice showed no difference in any of the circadian parameters tested. The enhanced sensitivity to phase-shifting stimuli in <em>Kcnma1</em><sup>N999S/WT</sup> and <em>Kcnma1</em><sup>D434G/D434G</sup> mice was similar to other <em>Kcnma1</em> GOF mice. Together with previous studies, these results suggest that increasing BK channel activity decreases circadian clock robustness, without rhythm ablation.</p>
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Se
ClinicalTrials.gov study NCT07249762. IPD Sharing: YES. Countries: 1. Publications: 11.
ROBUST I Pilot Study, Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
ClinicalTrials.gov study NCT03014726. IPD Sharing: NO. Countries: 1. Publications: 1.
ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
ClinicalTrials.gov study NCT03499964. IPD Sharing: NO. Countries: 2. Publications: 1.
Establishing a robust genetic sequencing and gene expression data library in cardiovascularly healthy cats
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Data from: Clustering Deviation Index (CDI): A robust and accurate internal measure for evaluating scRNA-seq data clustering
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Data from: Foraging-induced craniofacial plasticity is associated with an early, robust, and dynamic transcriptional response
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Data from: Robust phylogenomics settles controversies of classification and reveals evolution of male embolic complex of the Laufeia clade (Araneae, Salticidae, Euophryini)
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Data from: Aerobatic maneuvers in insect-scale flapping-wing aerial robots via deep-learned robust tube model predictive control
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Data from: From shadows to data: First robust population assessment of snow leopards in Pakistan
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Dataset: Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models
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Data from:Spatio-temporal networks: reachability, centrality and robustness
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Quartet-based computations of internode certainty provide robust measures of phylogenetic incongruence
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Data from: Robust quantification of fish early life CO2 sensitivities via serial experimentation
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Data from: Complex but clear allopolyploid pattern of subtribe Tussilagininae (Asteraceae: Senecioneae) revealed by robust phylogenomic evidence, with development of a novel homeolog-sorting pipeline
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Programmable assembly of mechanically robust and functional polymer–spore biocomposites in organic solvent
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Out-of-plane ferroelectricity and robust magnetoelectricity in quasi two-dimensional materials
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.