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2,848 results for “sequence data”
RNA sequencing data from breast precancerous and cancerous cells - Part2/3
<p>RNA sequencing data (fastq files) from breast precancerous and cancerous cell lines (total of 12 cell lines) as described in the paper entitled "CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse" by Taouk et al.</p> <p>The filename is "sample number_replicate number_overall sample number_read direction_001", where:</p> <p>- Sample number: represents the cell line (can be determined from supplementary figures 1, 3 and 5 of the above mentioned paper).</p> <p>- Replicate number: RNA from two independent experiments for each cell line (1 is for first replicate and 2 for the second replicate).</p> <p>- Overall sample number: random numbers given for all samples</p> <p>- Read direction: R1 (forward), R2 (reverse)</p> <p>This dataset (part2/3) contains fastq files for samples 5 to 8.</p>
Bulk sequencing data of osteosarcoma
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Comprehensive and realistic simulation of tumour genomic sequencing data.
<p>Simulated tumour genomic sequencing data relating to the publication "Comprehensive and realistic simulation of tumour genomic sequencing data."</p>
The molecular raw data of microbial communities associated with fish gut - in vitro model system using 16S rRNA Illumina amplicon sequencing approach.
<p>This data on the microbial communities and its diversity associated with fish gut. The samples were obtained from fish gut - in vitro model system using 16S rRNA Illumina amplicon sequencing approach.</p>
RNA sequencing data from breast precancerous and cancerous cells - Part3/3
<p>RNA sequencing data (fastq files) from breast precancerous and cancerous cell lines (total of 12 cell lines) as described in the paper entitled "CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse" by Taouk et al.</p> <p>The filename is "sample number_replicate number_overall sample number_read direction_001", where:</p> <p>- Sample number: represents the cell line (can be determined from supplementary figures 1, 3 and 5 of the above mentioned paper).</p> <p>- Replicate number: RNA from two independent experiments for each cell line (1 is for first replicate and 2 for the second replicate).</p> <p>- Overall sample number: random numbers given for all samples</p> <p>- Read direction: R1 (forward), R2 (reverse)</p> <p>This dataset (part3/3) contains fastq files for samples 9 to 12.</p>
The raw data of miRNA next-generation sequencing
<p>The raw data of miRNA next-generation sequencing</p>
Data from: Constraints on the evolution of toxin-resistant Na,K-ATPases have limited dependence on sequence divergence
<p>A growing body of theoretical and experimental evidence suggests that intramolecular epistasis is a major determinant of rates and patterns of protein evolution and imposes a substantial constraint on the evolution of novel protein functions. Here, we examine the role of intramolecular epistasis in the recurrent evolution of resistance to cardiotonic steroids (CTS) across tetrapods, which occurs via specific amino acid substitutions to the α-subunit family of Na,K-ATPases (ATP1A). After identifying a series of recurrent substitutions at two key sites of ATP1A that are predicted to confer CTS resistance in diverse tetrapods, we then performed protein engineering experiments to test the functional consequences of introducing these substitutions onto divergent species backgrounds. In line with previous results, we find that substitutions at these sites can have substantial background-dependent effects on CTS resistance. Globally, however, these substitutions also have pleiotropic effects that are consistent with additive rather than background-dependent effects. Moreover, the magnitude of a substitution's effect on activity does not depend on the overall extent of ATP1A sequence divergence between species. Our results suggest that epistatic constraints on the evolution of CTS-resistant forms of Na,K-ATPase likely depend on a small number of sites, with little dependence on overall levels of protein divergence. We propose that dependence on a limited number sites may account for the observation of convergent CTS resistance substitutions observed among taxa with highly divergent Na,K-ATPases.</p>
Data from: Constraints on the evolution of toxin-resistant Na,K-ATPases have limited dependence on sequence divergence
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.