Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,017
datasets available to search
ShareScore release 0.7.1
Dataset results
1,017 results for “Antimicrobial”
Fig. 3 in Undescribed specialised metabolites from the endophytic fungus Emericella sp. XL029 and their antimicrobial activities
Fig. 3. Key NOESY correlations of compounds 2–7. (Asterisk (*) indicates the partial structures of compounds).
Assessment of four in vitro phenotypic biofilm detection methods in relation to antimicrobial resistance in aerobic clinical bacterial isolates
<p><strong>Introduction</strong>: The lack of standardized methods for detecting biofilms continues to pose a challenge to microbiological diagnostics since biofilm-mediated infections induce persistent and recurrent infections in humans that often defy treatment with common antibiotics. This study aimed to evaluate diagnostic parameters of four in vitro phenotypic biofilm detection assays in relation to antimicrobial resistance in aerobic clinical bacterial isolates.</p> <p><strong>Methods</strong>: In this cross-sectional study, bacterial strains from clinical samples were isolated and identified following the standard microbiological guidelines. The antibiotic resistance profile was assessed through the Kirby-Bauer disc diffusion method. Biofilm formation was detected by gold standard tissue culture plate method (TCPM), tube method (TM), Congo red agar (CRA), and modified Congo red agar (MCRA). Statistical analyses were performed using SPSS version 17.0, with a significant association considered at p<0.05.</p> <p><strong>Result</strong>: Among the total isolates (n=226), TCPM detected 140 (61.95%) biofilm producers, with CoNS (9/9) (p<0.001) as the predominant biofilm former. When compared to TCPM, TM (n=119) (p<0.001) showed 90.8% sensitivity and 70.1% specificity, CRA (n=88) (p=0.123) showed 68.2% sensitivity and 42% specificity, and MCRA (n=86) (p=0.442) showed 65.1% sensitivity and 40% specificity. Juxtaposed to CRA, colonies formed on MCRA developed more intense black pigmentation from 24 to 96 hours. There were 77 multi-drug-resistant (MDR)-biofilm formers and 39 extensively drug-resistant (XDR)-biofilm formers, with 100% resistance to ampicillin and ceftazidime, respectively.</p> <p><strong>Conclusion</strong>: It is suggested that TM be used for biofilm detection. Unlike MCRA, black pigmentation in colonies formed on CRA declined with time. MDR- and XDR-biofilm formers were frequent among the clinical isolates.</p>
Fig. 1 in Antimalarial and antimicrobial substances isolated from the endophytic actinomycete, Streptomyces aculeolatus MS1-6
Fig. 1. Chemical structures of compounds isolated from the endophytic actinomycete, Streptomyces aculeolatus MS1-6.
Database for publication Costs and benefits of innovations able to reduce the use of Antimicrobials on Pig and Broiler Farms
<p>Database for publication Costs and Benefits of Innovations able to Reduce the Use of Antimicrobials on Pig and Broiler Farms HSOA Journal of Animal Research and Veterinary Science 2023 7:052</p>
Comparison of leaves and stem Aq. extract of Tridax Procumbens for antimicrobial activity
<p>In present study, aq. extracts of leaves and stem part of Tridax Procumbens were compared for antimicrobial activity. Firstly, all organoleptic and physicochemical properties of leaves and stem powder were evaluated and it shows that drug is pure and having required constituents sufficiently. Aq. extract of leaves powder and stem powder was prepared separately using Soxhlet extraction technique. Both the extracts were evaluated for physiochemical screening using standard procedures. Aq. extract of leaves shows presence of tannis, saponins, anthocyanin, coumarins, alkaloids, proteins, amino acids, diterpenes, phytosterol, cardial glycosides, phlobatannins and flavonoids. Aq. extract of stem shows presence of tannins, coumarins, phenol, cardial glycosides and flavonoids. Both extracts were primarily evaluated for antimicrobial activity against E.coli and S. aureus by selecting dose of 500 mg. Finally, antimicrobial assay was performed for both extracts (500mg) against E.coli and S. aureus by well diffusion method using Amoxicillin and Amikacin as standards respectively. Antimicrobial assay shows that aq. extract of stem part is more effective against S. aureus than E.coli; leaves aq. extract also shows antimicrobial activity against S .aureus and E.coli. From present studies we can conclude that aq. extract of stem and leaves of Tridax Procumbens having antimicrobial activity and stem extract is more effective against S. aureus as compared to leaf extract</p>
Clinical Evaluation and Antimicrobial Effect of Papain Based Chemo-mechanical Caries Removal Agents
ClinicalTrials.gov study NCT05983900. IPD Sharing: YES. Countries: 1. Publications: 1.
Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
ClinicalTrials.gov study NCT00114036. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Antimicrobial Stewardship in UTIs in Nursing Homes
ClinicalTrials.gov study NCT04798365. IPD Sharing: NO. Countries: 1. Publications: 1.
Efficacy and Cost-effectiveness of Hospital Antimicrobial Stewardship Programs
ClinicalTrials.gov study NCT02814877. IPD Sharing: NO. Countries: 1. Publications: 2.
Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds
ClinicalTrials.gov study NCT06876259. IPD Sharing: NO. Countries: 1. Publications: 4.
Interventional Study of Mucosal and Antimicrobial Responses to Repeated Vaginal Applications of Tenofovir Gel in HIV Uninfected Women
ClinicalTrials.gov study NCT00594373. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe
ClinicalTrials.gov study NCT05541081. IPD Sharing: YES. Countries: 1. Publications: 3.
Intravenous Versus Combined Oral and Intravenous Antimicrobial Prophylaxis for the Prevention of Surgical Site Infection in Elective Colorectal Surgery
ClinicalTrials.gov study NCT02618720. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Evaluation of Antimicrobial Photodynamic Therapy and Minimal Intervention Associated With Deproteinization in Permanent Teeth With Molar Incisor Hypomineralization
ClinicalTrials.gov study NCT05443035. IPD Sharing: YES. Countries: 1. Publications: 1.
Efficacy and Safety of Antimicrobial Durations Treatment of Infections Associated With Osteosynthesis Material
ClinicalTrials.gov study NCT05294796. IPD Sharing: NO. Countries: 1. Publications: 1.
The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study
ClinicalTrials.gov study NCT05655689. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
A Multicentre Pilot Study of Midline Catheter's Tip at a Different Position in Antimicrobial Therapy
ClinicalTrials.gov study NCT04601597. IPD Sharing: NO. Countries: 1. Publications: 16.
Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles
ClinicalTrials.gov study NCT06124235. IPD Sharing: YES. Countries: 1. Publications: 1.
Trial of Antimicrobial Restraint in Presumed Pneumonia
ClinicalTrials.gov study NCT04438187. IPD Sharing: NO. Countries: 1. Publications: 30.
Clinical/Microbiological Impact of a Specific Antimicrobial Stewardship Program for Nursing Homes
ClinicalTrials.gov study NCT03543605. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.