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897
datasets available to search
ShareScore release 0.9.0
Dataset results
897 results for “Therapeutic targets”
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development)
GEO Series GSE71800. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Targeting the PDGFRa-SHP2 Signaling Enhances Therapeutic Effect of Radiotherapy on Treating IDH1 Mutant Glioma
GEO Series GSE277548. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Pre-clinical spheroid models identify BMX as a therapeutic target for metastatic MYCN non-amplified neuroblastoma (RNA-Seq)
GEO Series GSE223900. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
CDK12 tumor suppressor function and therapeutic targeting in newly developed mouse models of serous ovarian cancer
GEO Series GSE284088. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases
GEO Series GSE123088. Homo sapiens. 204 samples. Type: Expression profiling by array.
The histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target in BRAF/MEK inhibitor-resistant melanoma [HT144]
GEO Series GSE109669. Homo sapiens. 8 samples. Type: Expression profiling by array.
ChIP-seq dataset for H3K9ac in Identifying Novel Therapeutic Targets by Combining Transcriptional Data with Ordinal Clinical Measurements
GEO Series GSE98738. Mus musculus. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Lurbinectedin is an effective therapeutic target for de novo and transformed small cell lung cancer and modulates EMT and NOTCH signaling pathways.
GEO Series GSE223372. Homo sapiens. 61 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic targeting of BRD4 in head neck squamous cell carcinoma
GEO Series GSE122522. Homo sapiens. 4 samples. Type: Expression profiling by array.
Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target
GEO Series GSE164939. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
OPTN as a therapeutic target for acetaminophen-induced liver injury by activating mitophagy
GEO Series GSE195753. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway via stimulating MSK1 kinase and suppressing PPP2R2B protein
GEO Series GSE150223. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Selective therapeutic targeting of the first and second bromodomains of the BET proteins in cancer and immuno-inflammation [SLAM-seq]
GEO Series GSE138209. Homo sapiens. 66 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic targeting of the GSK3b-CUGBP1 pathway in Myotonic Dystrophy
GEO Series GSE230821. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Novel therapeutic strategy targeting STMN1 using chlorambucil-conjugated pyrrole-imidazole polyamide in small cell lung cancer
GEO Series GSE281782. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Discovery, delineation and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome [Monocytes_Ribo-seq]
GEO Series GSE287444. Homo sapiens. 4 samples. Type: Other; Expression profiling by high throughput sequencing.
Multiomic Profile Integration Reveals Early Signatures of Amyotrophic Lateral Sclerosis and Suggests the MAPK Pathway as a Therapeutic Target [miRNA-Seq]
GEO Series GSE234243. Mus musculus. 79 samples. Type: Non-coding RNA profiling by high throughput sequencing.
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer
GEO Series GSE72483. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human
GEO Series GSE155514. Mus musculus; Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
GEO Series GSE178737. Homo sapiens. 2 samples. Type: Methylation profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.