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Data from: Labor market integration of people with disabilities: results from the Swiss Spinal Cord Injury Cohort Study
Objectives: We aimed to describe labor market participation (LMP) of persons with spinal cord injury (SCI) in Switzerland, to examine potential determinants of LMP, and to compare LMP between SCI and the general population. Methods: We analyzed data from 1458 participants of employable age from the cross-sectional community survey of the Swiss Spinal Cord Injury Cohort Study. Data on LMP of the Swiss general population were obtained from the Swiss Federal Statistics Office. Factors associated with employment status as well as the amount of work performed in terms of full-time equivalent (FTE) were examined with regression techniques. Results: 53.4% of the participants were employed at the time of the study. Adjusted odds of being employed were increased for males (OR=1.73, 95% CI 1.33 - 2.25) and participants with paraplegia (OR=1.78, 95% CI 1.40 - 2.27). The likelihood of being employed showed a significant concave relationship with age, peaking at age 40. The relation of LMP with education was s-shaped, while LMP was linearly related to time since injury. On average, employment rates were 30% lower than in the general population. Males with tetraplegia aged between 40 and 54 showed the greatest difference. From the 771 employed persons, the majority (81.7%) worked part-time with a median of 50% FTE (IRQ: 40%-80%). Men, those with younger age, higher education, incomplete lesions, and non-traumatic etiology showed significantly increased odds of working more hours a week. Significantly more people worked part-time than in the general population with the greatest difference found for males with tetraplegia aged between 40 and 54. Conclusions: LMP of persons with SCI is comparatively high in Switzerland. LMP after SCI is, however, considerably lower than in the general population. Future research needs to show whether the reduced LMP in SCI reflects individual capacity adjustment, contextual constraints or both on higher LMP.
Data from: Association of body mass index and age with incident diabetes in Chinese adults: a population-based cohort study
Objective. Type 2 diabetes mellitus is increasing in young adults, and greater adiposity is considered a major risk factor. However, whether there is an association between obesity and diabetes and how this might be impacted by age is not clear. Therefore, we investigated the association between body mass index (BMI) and diabetes across a wide range of age groups (20-30, 30-40, 40-50, 50-60, 60-70, ≥70 years old). Design. We performed a retrospective cohort study using healthy screening program data. Setting. A total of 211,833 adult Chinese persons > 20-years-old across 32 sites and 11 cities in China (Shanghai, Beijing, Nanjing, Suzhou, Shenzhen, Changzhou, Chengdu, Guangzhou, Hefei, Wuhan, Nantong) were selected for the study; these persons were free of diabetes at baseline. Primary and secondary outcome measures. Fasting plasma glucose levels were measured and information regarding the history of diabetes was collected at each visit. Diabetes was diagnosed as fasting plasma glucose ≥ 7.00 mmol/L and/or self-reported diabetes. Patients were censored at the date of diagnosis or the final visit, whichever came first. Results. With a median follow-up of 3.1 years, 4,174 of the 211,833 participants developed diabetes, with an age-adjusted incidence rate of 7.35 per 1,000 persons. The risk of incident diabetes increased proportionally with increasing baseline BMI values, with a 23% increased risk of incident diabetes with each kg/m2 increase in BMI (95%CI: 1.22, 1.24). Across all age groups, there was a linear association between BMI and the risk of incident diabetes, although there was a stronger association between BMI and incident diabetes in the younger age groups (age × BMI interaction, P < 0.0001). Conclusions. An increased BMI is also independently associated with a higher risk of developing diabetes in young adults and the effects of BMI on incident diabetes were accentuated in younger adults.
Data from: Circulating cortisol and cognitive and structural brain measures in a middle-aged cohort: the Framingham Heart Study
Objective: To assess the association of early morning serum cortisol with cognitive performance and brain structural integrity in community-dwelling young and middle-aged adults without dementia. Methods: We evaluated dementia-free Framingham Study (Generation 3) participants (mean age 48.5 years; 46.8% men), who underwent cognitive testing for memory, abstract reasoning, visual perception, attention, and executive function (n= 2231), and brain MRI (n=2018) to assess total white matter, lobar gray matter, and white matter hyperintensity volumes and fractional anisotropy (FA) measures. We used linear and logistic regression to assess the relations of cortisol (categorized in tertiles, with the middle tertile as referent) to measures of cognition, MRI volumes, presence of covert brain infarcts (CBI) and cerebral microbleeds (CMB), and voxel-based microstructural white matter integrity and gray matter density, adjusting for age, sex, APOE and vascular risk factors. Results: Higher cortisol (highest tertile vs. middle tertile) was associated with worse memory and visual perception, as well as lower total cerebral brain, occipital and frontal lobar gray matter volumes. Higher cortisol was associated with multiple areas of microstructural changes (decreased regional FA), especially in the splenium of corpus callosum and the posterior corona radiata. The association of cortisol with total cerebral brain volume varied by sex (p interaction=0.048); higher cortisol was inversely associated with cerebral brain volume in women [p=0.001] but not in men [p=0.717]). There was no effect modification by the apoE4 genotype of the relations of cortisol and cognition or imaging traits. Conclusions: Higher serum cortisol was associated with lower brain volumes and impaired memory in asymptomatic younger to middle-aged adults, with the association being evident particularly in women.
Data from: An investigation of sepsis surveillance and emergency treatment on patient mortality outcomes: an observational cohort study
Objective. To determine the prevalence of initiating the sepsis 3-hour bundle of care and estimate effects of bundle completion on risk-adjusted mortality among ED patients screened-in by electronic surveillance. Materials and Methods. This was a multiple center observational cohort study conducted in 2016. The study population was comprised of patients screened-in by St. John Sepsis Surveillance Agent within four hours of ED arrival, had a sepsis bundle initiated, and admitted to hospital. We built multivariable logistic regression models to estimate impact of a 3-hour bundle completed within three hours of arrival on mortality outcomes. Results. Approximately 3% ED patients were screened-in by electronic surveillance within four hours of arrival and admitted to hospital. Nearly 7 in 10 (69%) patients had a bundle initiated, with most bundles completed within three hours of arrival. The fully-adjusted risk model achieved good discrimination on mortality outcomes (AUROC = .82, 95% CI = .79 to .85) and estimated 34% reduced mortality risk among patients with a bundle completed within three hours of arrival compared to non-completers. Discussion. The sepsis bundle is an effective intervention for many vulnerable patients, and likely to be completed within three hours after arrival when electronic surveillance with reliable alert notifications are integrated into clinical workflow. Beginning at triage, the platform and sepsis program enables identification and management of patients with greater precision, and increases the odds of good outcomes. Conclusion. Sepsis surveillance and clinical decision support accelerate accurate recognition and stratification of patients, and facilitate timely delivery of healthcare.
Data from: The incidence of admissions for schizophrenia and related psychoses in two cohorts: 1875-1924 and 1994-2010
OBJECTIVES: To investigate changes in incidence of admissions for schizophrenia and related non-affective psychoses in North Wales. DESIGN: Data from two epidemiologically complete cohorts of patients presenting for the first time to mental health services in North Wales between 1875-1924 and 1994-2010 are used in this study to map the incidence of hospital admissions for schizophrenia and non-affective psychoses. SETTING: The North Wales Asylum Denbigh (archived patient case notes) and the North West Wales District General Hospital psychiatric unit. POPULATION: 3168 patients admitted to the North Wales Asylum Denbigh 1875-1924 and 355 patients admitted to the District General Hospital psychiatric unit 1994-2010. RESULTS: There was an increasing admission incidence for schizophrenia between 1875 and 1900, a higher admission rate in the 1990s for males, followed by a drop in rates of admission for both genders since 2006. Admission incidences switch from parity between the sexes in the historical period to a doubling of the admission rates for men compared to women in the modern period. This admission pattern differs from the admission patterns for affective psychoses or organic disorders. CONCLUSION: There have been changes in the incidence of admissions for schizophrenia in North Wales.
Data from: Reducing early infant mortality in India: results of a prospective cohort of pregnant women utilizing emergency medical services
Objectives: To describe the demographic characteristics and clinical outcomes of neonates born within 7 days of public ambulance transport to hospitals across five states in India. Design: Prospective observational study. Setting: Five Indian states using a centralised EMS agency that transported 3.1 million pregnant women in 2014. Participants: Over 6 weeks in 2014, this study followed a convenience sample of 1,431 neonates born to women utilizing a public-private ambulance service for a 'pregnancy related' problem. Initial calls were deemed 'pregnancy related' if categorised by EMS dispatchers as 'pregnancy', 'childbirth', 'miscarriage' or 'labour pains'. Interfacility transfers, patients absent on ambulance arrival, refusal of care, and neonates born to women beyond 7 days of using the service were excluded. Main outcome measures: Death at 2, 7 and 42 days after delivery. Results: Among 1,684 women, 1,411 gave birth to 1,431 newborns within 7 days of initial ambulance transport. Median maternal age at delivery was 23 years (IQR: 21-25). Most mothers were from rural/tribal areas (92.5%) and lower social (79.9%) and economic status (69.9%). Follow-up rates at 2, 7 and 42 days were 99.8%, 99.3% and 94.1%, respectively. Cumulative mortality rates at 2, 7 and 42-days follow-up were 41, 53 and 62 per 1000 births, respectively. The perinatal mortality rate (PMR) was 53 per 1000. Preterm birth [OR: 2.89, 95% CI: 1.67-5.00], twin deliveries (OR: 2.80, 95% CI: 1.10-7.15), and cesarean section (2.21, 95% CI: 1.15-4.23) were the strongest predictors of mortality. Conclusions: The perinatal mortality rate associated with this cohort of patients with high-acuity conditions of pregnancy was nearly two times the most recent rate for India as a whole (28 per 1000 births). EMS data has the potential to provide more robust estimates of PMR, reduce inequities in timely access to healthcare, and increase facility-based care through service of marginalized populations.
Data from: Linkage into care among newly diagnosed HIV-positive individuals tested through outreach and facility-based HIV testing models in Mbeya, Tanzania: a prospective mixed-method cohort study
Objective: Linkage to care is the bridge between HIV testing and HIV treatment, care and support. In Tanzania, mobile testing aims to address historically low testing rates. Linkage to care was reported at 14% in 2009 and 28% in 2014. The study compares linkage to care of HIV-positive individuals tested at mobile/outreach versus public health facility-based services within the first 6 months of HIV diagnosis. Setting: Rural communities in four districts of Mbeya Region, Tanzania. Participants: A total of 1012 newly diagnosed HIV-positive adults from 16 testing facilities were enrolled into a two-armed cohort and followed for 6 months between August 2014 and July 2015. 840 (83%) participants completed the study. Main outcome: measures We compared the ratios and time variance in linkage to care using the Kaplan-Meier estimator and Log rank tests. Cox proportional hazards regression models to evaluate factors associated with time variance in linkage. Results: At the end of 6 months, 78% of all respondents had linked into care, with differences across testing models. 84% (CI 81% to 87%, n=512) of individuals tested at facility-based site were linked to care compared to 69% (CI 65% to 74%, n=281) of individuals tested at mobile/outreach. The median time to linkage was 1 day (IQR: 1–7.5) for facility-based site and 6 days (IQR: 3–11) for mobile/outreach sites. Participants tested at facility-based site were 78% more likely to link than those tested at mobile/outreach when other variables were controlled (AHR=1.78; 95% CI 1.52 to 2.07). HIV status disclosure to family/relatives was significantly associated with linkage to care (AHR=2.64; 95% CI 2.05 to 3.39). Conclusions: Linkage to care after testing HIV positive in rural Tanzania has increased markedly since 2014, across testing models. Individuals tested at facility-based sites linked in significantly higher proportion and modestly sooner than mobile/outreach tested individuals. Mobile/outreach testing models bring HIV testing services closer to people. Strategies to improve linkage from mobile/outreach models are needed.
Data from: Delays and loss to follow up before treatment of drug-resistant TB following implementation of Xpert MTB/RIF in South Africa: a retrospective cohort study
Background: South Africa has a large burden of rifampicin-resistant tuberculosis (RR-TB), with 18,734 patients diagnosed in 2014. The number of diagnosed patients has increased substantially with the introduction of the Xpert MTB/RIF test, used for TB diagnosis for all patients with presumptive TB. Routine aggregate data suggest a large treatment gap (pre-treatment loss to follow up) between the numbers of laboratory confirmed RR-TB patients and those reported to have started second-line treatment. We aimed to assess the impact of Xpert MTB/RIF implementation on the delay to treatment initiation and loss to follow-up before second-line treatment for RR-TB across South Africa. Methods and findings: A nationwide retrospective cohort study was conducted to assess second-line treatment initiation and treatment delay among laboratory diagnosed RR-TB patients. Cohorts, including approximately 300 sequentially diagnosed RR-TB patients per South African province, were drawn from 2011 and 2013, before and after Xpert implementation. Patients with prior laboratory RR-TB diagnoses within 6 months and currently treated patients were excluded. Treatment initiation was determined through data linkage with national and local treatment registers, medical record review, interviews with healthcare staff, and direct contact with patients or household members. Additional laboratory data were used to track cases. National estimates of percentage treatment initiation and time to treatment were weighted to account for the sampling design. There were 2,508 and 2,528 eligible patients in the 2011 and 2013 cohorts respectively; 92% were newly diagnosed with RR-TB (new RR-TB, no prior RR-TB diagnoses). Nationally, among 2,340 and 2,311 new RR-TB patients in the 2011 and 2013 cohorts, 55% (95% CI 53-57) and 63% (95% CI 61-65) respectively started treatment within 6 months of their diagnostic specimen being sent (p<0.001). However, in 2013, there was no difference in the percentage of patients who initiated treatment at six months between the 1,368174 new RR-TB patients diagnosed by Xpert (62%, 95% CI 59-65) and the 943ose diagnosed by other methods (64%, 95% CI 61-67) (p=0.39). The median time to treatment decreased from 44 (IQR 20-69) days in 2011 to 22 (IQR 2-43) days in 2013 (p<0.001). In 2013, across the nine provinces, there were substantial variations in both treatment initiation (range 51-73% by six months) and median time to treatment (range 15-36 days, N=1,450), and only 53% of 1,448 new RR-TB who received treatmented patients were recorded on the national RR-TB register. This retrospective study is limited by the lack of information to assess reasons for non-initiation of treatment, particularly pre-treatment mortality data. Other limitations include the use of names and dates of birth to locate patient-level data, potentially resulting in missed treatment initiation among some patients. Conclusions: In 2013, there was a large treatment gap for RR-TB in South Africa which varied significantly across provinces. Xpert implementation, while reducing treatment delay, had not contributed substantially to reducing the treatment gap in 2013. However, given improved case detection with Xpert, overall a larger proportion of the total RR-TB burden has received treatment, with reduced delays. Nonetheless, strategies to further improve linkage to treatment for all diagnosed RR-TB patients are urgently required.
Data from: Clinical characteristics and lipid lowering treatment of patients initiated on Proprotein convertase subtilisin/kexin type 9 inhibitors – a nationwide cohort study
Objectives: Given the novelty of proprotein convertase subtilisin–kexin type 9 inhibitors (PCSK9i), little is known regarding overall implementation or clinical characteristics among patients who initiate treatment. We aimed to assess the total number of patients initiated on PCSK9i along with a description of the clinical characteristics and lipid lowering treatment (LLT) of such patients. Setting: A register based descriptive cohort study of patients receiving a PCSK9i in the time period from 01-01-2016 to 31-03-2017 using a cross-linkage between three nationwide Danish registers. Information regarding PCSK9i prescriptions, patient demographics, concurrent pharmacotherapy, comorbidities, and previous coronary procedures was identified. Results: Overall, 137 patients initiated treatment with PCSK9i in the study period from 11 in the first quarter of 2016 to 40 in the first quarter of 2017. The majority had a history of ischemic heart disease (67.9%) with ischemic stroke and diabetes mellitus being present in 7.3% and 16.8% of patients, respectively. All patients initiated on PCSK9i had been previous prescribed statin treatment with Atorvastatin and Simvastatin being most frequently prescribed in 53% and 36% of patients, respectively. The majority of patients had received both statins and Ezetimibe (94.9%) and approximately half of these patients had also received bile acid sequestrant (45.3%). Clinical characteristics mainly differed in patients receiving triple LLT compared to patients not receiving triple LLT in the regards of heart failure. Conclusion: Patients treated with PCSK9i were rare, characterized by having ischemic heart disease and had received various and intensive conventional LLT prior to PCSK9i initiation in agreement with current international guidelines.
Clinical Usefulness of Capnographic Monitoring for Feeding Tube Insertion in Critically Ill Patients: Retrospective Cohort Study
<p><strong>Background</strong>: It is not rare for a small-bore feeding tube to be inserted incorrectly into the respiratory system in critically ill patients. Thus, monitoring is necessary to prevent respiratory malplacement of the tube. We investigated the utility of capnographic monitoring for the prevention of respiratory complications due to feeding tube mispositioning in critically ill patients.</p> <p><strong>Methods:</strong> This study is a pre- and post-intervention study, including a total of 445 feeding tube placements events that were retrospectively studied in the medical and surgical intensive care units of the Samsung Medical Center. We compared the outcomes between the time periods before and after the capnographic monitoring and respiratory complications.</p> <p><strong>Results:</strong> Feeding tubes were inserted in 275 cases without capnographic monitoring. Capnographic monitoring was performed in 170 cases. Sixteen patients (4%) had respiratory complications in total tube placements. Tracheal insertion was in 11 (2%) patients and pneumothorax in 5 (1%) patients. Fourteen cases of respiratory complications were detected in control group (14/275, 5%, ten tracheal insertions and four pneumothoraxes). Two cases of respiratory complications were detected in the capnographic monitoring group (2/170, 1%, one tracheal insertions and one pneumothorax). Respiratory complications were less detected in capnographic monitoring group than control group.</p> <p><strong>Conclusions:</strong> Capnographic monitoring is simple, easy to learn, and may be useful to prevent respiratory complication during feeding tube insertion in critically ill patients.</p>
Supplemental Materials - Performance Figures for "A Model for Predicting the (re)-occurrence of a ≥40% eGFR Decline in a large Population-based cohort of Persons with or At-Risk of Chronic Kidney Disease " paper
<p>The zip file contains performance metrics figures for each dynamic Bayesian Network (DBN) model, stratified by comorbidities, race, CKD stages, and ethnicity.</p> <p>Contains:</p> <ul> <li>Stratified: Bootstrapping of 1000 iterations and 1000 samples with stratified proportions (as in the original population of the test set) of rapid eGFR decliners and non-decliners.</li> </ul> <p> </p> <p>Second zip contains DBN structures as matrices for 2 periods study entry to entry period and entry period to year 1 for all sites in 2 excel files.</p>
Replication package for: "Economic Distress and Children's Mental Health: Evidence from the Brazilian High Risk Cohort Study for Mental Conditions"
<p>This package replicates the results of "Economic distress and children's mental health: evidence from the Brazilian High Risk Cohort Study for Mental Conditions" (and its respective online appendix) using mostly Stata. The package does not include the paper's main dataset, which is confidential.</p>
Comparison of Clinical Efficacy and Safety of Amnio-Graft Versus Skin Graft in Injury Patients: Retrospective Cohort Study
<p>Al Mujtahid Hospital, Damascus, Syria</p><p><strong>Title of the Study</strong>: Comparison of Clinical Efficacy and Safety of Amnio-Graft versus Skin Graft in Plastic Surgery</p><p><strong>Principal Investigator</strong>: Dr. Wael Barazi, President of the Plastic Surgery Department</p><p><strong>Study Duration</strong>: From February 19, 2023, to October 23, 2023</p><p>I. <strong>Background and Rationale</strong>:</p><p>Plastic surgery, a rapidly evolving field, continuously explores novel techniques to enhance patient outcomes. This retrospective cohort study aims to compare the clinical efficacy and safety of amnio-graft and skin graft procedures performed in the Plastic Surgery Department of Al Mujtahid Hospital in Damascus, Syria.</p><p>II.<strong> Objectives</strong>:</p><p>To assess the clinical efficacy of amnio-graft and skin graft procedures.</p><p>To evaluate the safety profile of amnio-graft and skin graft procedures.</p><p>To compare the outcomes of patients undergoing plastic surgery with amnio-graft versus skin graft.</p><p>III. <strong>Study Design</strong>:</p><p>This study will adopt a retrospective cohort design, analyzing data collected from patient records in the Plastic Surgery Department during the specified study duration.</p><p>IV. Participants:</p><p>The study will include all patients who underwent either amnio-graft or skin graft procedures within the defined study period.</p><p>V. <strong>Data Collection</strong>:</p><p>Primary Data:</p><p>Patient demographics</p><p>Preoperative clinical characteristics</p><p>Surgical details</p><p>Postoperative outcomes</p><p>Adverse events</p><p>Secondary Data:</p><p>Histopathological findings</p><p>Follow-up information</p><p>Hospitalization duration</p><p>Any additional relevant clinical information</p><p>VI. <strong>Data Analysis</strong>:</p><p>Statistical analysis will be conducted to compare clinical outcomes and safety profiles between the amnio-graft and skin graft groups. Descriptive statistics, such as mean, median, and standard deviation, will be used, and inferential statistics, including chi-square tests and t-tests, will be applied where appropriate.</p><p>VII. <strong>Ethical Considerations:</strong></p><p>Patient Confidentiality:</p><p>All patient information will be kept confidential, with data anonymized during analysis.</p><p><strong>Informed Consent:</strong></p><p>As this is a retrospective study, no new interventions will be performed. Informed consent will not be obtained.</p><p><strong>Patient Welfare:</strong></p><p>Patient welfare and safety are paramount. The study design aims to minimize risks associated with data collection.</p><p><strong>VIII. Potential Risks and Benefits:</strong></p><p><strong>Risks</strong>:</p><p>There are no additional risks associated with this retrospective study as it involves the analysis of existing medical records.</p><p><strong>Benefits</strong>:</p><p>The study results may contribute to improved decision-making in plastic surgery procedures, enhancing patient outcomes.</p><p><strong>IX. Approval</strong>:</p><p>This research protocol has been reviewed and approved by the Institutional Review Board (IRB) of Al Mujtahid Hospital.</p><p>IRB Approval Date: [27/11/2023]</p><p>IRB Approval Code: [<strong>63211</strong>]</p><p><i>Note: Any amendments to this protocol will require additional review and approval by the Institutional Review Board.</i></p><p> </p>
Blood-based epigenome–wide analyses of chronic low–grade inflammation across diverse population cohorts
<p>Authors: Robert F. Hillary, Hong Kiat Ng, Daniel L. McCartney, Hannah R. Elliott, Rosie M. Walker, Archie Campbell, Felicia Huang, Kenan Direk, Paul Welsh, Naveed Sattar, Janie Corley, Caroline Hayward, Andrew M. McIntosh, Cathie Sudlow, Kathryn L. Evans, Simon R. Cox, John C. Chambers, Marie Loh, Caroline L. Relton, Riccardo E. Marioni, Paul D. Yousefi, Matthew Suderman</p> <p>Epigenome-wide association studies were performed on log-transformed blood C-reactive protein levels in Generation Scotland. Log-transformed CRP was the outcome. CpG beta-values were the exposure and were measured using the EPIC array (n=752,722 sites). </p> <p>A basic model adjusted for age, sex, experimental batch and Houseman-estimated white blood cell proportions. A fully-adjusted model further adjusted for alcohol consumption (units/week), log-transformed body mass index (kg/m2), education (11-category ordinal variable), deprivation (Scottish Index of Multiple Deprivation), EpiSmokEr (a methylation-based surrogate score for cigarette smoking) and 20 genetic principal components (to control for population structure).</p>
Differential cross-reactivity to the influenza B virus haemagglutinin underpins lineage-specific susceptibility between birth cohorts
<p>Data and code relataing to "Differential cross-reactivity to the influenza B virus haemagglutinin underpins lineage-specific susceptibility between birth cohorts" Edler et al study https://www.biorxiv.org/content/10.1101/2023.08.25.554879v1<br><br></p> <p> </p>
Fig. 1. Colonial ISoxYa manangona n in Discovery and Genetic Characterization of Single Cohort Adult Colonies With Male Aggregations, and Preliminary Evidence for Lekking in a Malagasy Kite Spider (Isoxya,
Fig. 1. Colonial ISoxYa manangona n. sp. from Andasibe, Madagascar. (a) A part of a colony with 79 spiders in 41 webs (image shows 23 webs). (b) A detail from another colony where females are in their individual webs (image shows 14 of the 16 webs in the colony) while males hang on line in between webs (image shows 12 males). (c) A detail of another colony showing male leks.These males showed no overt intrasexual aggression that would be typical of solitary spiders.
Fig. 26 in Discovery and Genetic Characterization of Single Cohort Adult Colonies With Male Aggregations, and Preliminary Evidence for Lekking in a Malagasy Kite Spider (Isoxya,
Fig. 26. Clustering of individuals from the nine web colonies (A–I) based on discriminant analysis of principal components from unlinked SNPs.
Plate 2. Figs. 9–17 in Discovery and Genetic Characterization of Single Cohort Adult Colonies With Male Aggregations, and Preliminary Evidence for Lekking in a Malagasy Kite Spider (Isoxya,
Plate 2. Figs. 9–17. Male: dorsal (Fig. 9), ventral (Fig. 10), side (Fig. 11); palp: dorsal (Fig. 12), ventral (Fig. 13), retrolateral (Fig. 14), prolateral (Fig. 15); line drawings: dorsal palp (Fig. 16), median apophysis (Fig. 17).
Plate 3. Figs. 18–25 in Discovery and Genetic Characterization of Single Cohort Adult Colonies With Male Aggregations, and Preliminary Evidence for Lekking in a Malagasy Kite Spider (Isoxya,
Plate 3. Figs. 18–25. Female: melanic dorsal (Fig. 18), ventral (Fig. 19); light dorsal (Fig. 20), ventral (Fig. 21); Male: melanic dorsal (Fig. 22), ventral (Fig. 23); light dorsal (Fig. 24), ventral (Fig. 25).
Fig. 28 in Discovery and Genetic Characterization of Single Cohort Adult Colonies With Male Aggregations, and Preliminary Evidence for Lekking in a Malagasy Kite Spider (Isoxya,
Fig. 28. Unsupervised machine learning clustering analysis based on unlinked SNPs using variational autoencoders. Colors for individuals are based on the web colony (A–I) from which they were collected.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.