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4,486 results for “emergence”
Developing elastic mechanisms: Ultrafast motion and cavitation emerge at the millimeter scale in juvenile snapping shrimp
<p>Organisms such as jumping froghopper insects and punching mantis shrimp use spring-based propulsion to achieve fast motion. Studies of elastic mechanisms primarily focus on fully developed and functional mechanisms in adult organisms. However, the ontogeny and development of these mechanisms can provide important insights into lower size limits of spring-based propulsion, the ecological or behavioral relevance of ultrafast movement, and the scaling of ultrafast movement. Here we examine the development of the spring-latch mechanism in the big claw snapping shrimp, <em>Alpheus</em> <em>heterochaelis</em> (Alpheidae). Adult snapping shrimp use an enlarged claw to produce high-speed strikes that generate cavitation bubbles. However, until now, it was unclear when the elastic mechanism emerges during development and whether juvenile snapping shrimp can generate cavitation at this size. We reared <em>A</em>. <em>heterochaelis</em> from eggs, through their larval and postlarval stages. Starting one month after hatching, the snapping shrimp snapping claw gradually developed a spring-actuated mechanism and began snapping. We used high-speed videography (300,000 frames s<sup>-1</sup>) to measure juvenile snaps. We discovered that juvenile snapping shrimp generate the highest recorded accelerations (5.8x10<sup>5</sup> ± 3.3x10<sup>5</sup> m s<sup>-2</sup>) for repeated use and underwater motion and are capable of producing cavitation at the millimeter scale. The angular velocity of snaps did not change as juveniles grew; however, juvenile snapping shrimp with larger claws produced faster linear speeds and generated larger, longer-lasting cavitation bubbles. These findings establish the development of the elastic mechanism and cavitation in snapping shrimp and provide insights into early life-history transitions in spring-actuated mechanisms.</p>
Spatial transcriptomics stratifies health and psoriatic disease severity by emergent cellular ecosystems
<p>While human inflammatory skin diseases' cellular and molecular features are well-characterized, their tissue context and systemic impact remain poorly understood. We thus profiled human psoriasis (PsO) as a prototypic immune-mediated condition with a high preference for extra-cutaneous involvement. Spatial transcriptomics (ST) analyses of 25 healthy, active, and clinically uninvolved skin biopsies, and integration with public single-cell transcriptomics data revealed striking differences in immune microniches between healthy and inflamed skin. Tissue scale-cartography further identified core disease features across all active lesions, including the emergence of an inflamed suprabasal epidermal state and the presence of B lymphocytes in lesional skin. Notably, both lesional and distal non-lesional samples were stratified by skin disease severity, and not by the presence of systemic disease. This segregation was driven by macrophage-, fibroblast- and lymphatic-enriched spatial regions with gene signatures associated with metabolic dysfunction. Taken together, these findings suggest that mild and severe forms of PsO have distinct molecular features and that severe PsO may profoundly alter the cellular and metabolic make up of distal unaffected skin sites. Additionally, our study provides an unprecedented resource for the research community to study spatial gene organization of healthy and inflamed human skin. </p>
Dataset of chemicals of emerging concern (CECs) in surface water in the Swedish west coast (Stenungsund)
<p>This repository encompasses the environmental concentrations of emerging chemical contaminants (CECs) present in surface water samples obtained from the west coast of Sweden, specifically Stenungsund.</p>
Local response and emerging nonlinear elastic length scale in biopolymer matrices
<p>Dataset corresponding to the underlying numerical and experimental data of the research article "Local response and emerging nonlinear elastic length scale in biopolymer matrices". </p> <p>This repository contains four categories of data, each contained in a folder: <br> - Fiber Network Simulations <br> - Finite Elements Simulations <br> - Optical Tweezer Experiments<br> - Traction Force Microscopy<br> In each folder, a README.txt document provides a detailed description of the content.</p> <p>We would like to acknowledge the support from the NIH (1R01GM140108), MathWorks, and the Jeptha H. and Emily V. Wade Award at the Massachusetts Institute of Technology. H.Y. acknowledges the MathWorks Mechanical Engineering Fellowship. M.G. acknowledges the Sloan Research Fellowship. This project received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement no. 891217 and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Project-ID 201269156 - SFB 1032 (Project B12) (E.B. and C.P.B.). P.R. is supported by France 2030, the French National Research Agency (ANR-16-CONV-0001), and the Excellence Initiative of Aix- Marseille University—A*MIDEX.</p>
Consensus recommendations for opioid agonist treatment following the introduction of emergency clinical guidelines in Ireland during the COVID-19 pandemic: A national Delphi study
<p>Anonymous Delphi survey likert scale responses (round 1 (S1-S32) and 2 (R2S1-R2S15)) <a href="https://zenodo.org/api/files/92371fe3-6af6-4044-ba3f-83a26b2fe471/Delphi_likert_responses_ano.csv?versionId=7c3aaa7b-8b43-43da-bfeb-fe644f33d3e2">Delphi_likert_responses_ano.csv</a> and corresponding statements in <a href="https://zenodo.org/api/files/92371fe3-6af6-4044-ba3f-83a26b2fe471/STATEMENTS_REPO.csv?versionId=ada85e7c-ba48-4f61-8e1a-d90dab9b4f05">STATEMENTS_REPO.csv</a>.</p>
Cortical topographic motifs emerge in a self-organized map of object space
<p>The human ventral visual stream has a highly systematic organization of object information, but the causal pressures driving these topographic motifs are highly debated. Here, we use self-organizing principles to learn a topographic representation of the data manifold of a deep neural network representational space. We find that a smooth mapping of this representational space showed many brain-like motifs, with large-scale organization by animacy and real-world object size, supported by mid-level feature tuning, with naturally emerging face- and scene-selective regions. While some theories of the object-selective cortex posit that these differently tuned regions of the brain reflect a collection of distinctly specified functional modules, the present work provides computational support for an alternate hypothesis that the tuning and topography of the object-selective cortex reflects a smooth mapping of a unified representational space.</p>
Dataset of chemicals of emerging concern detected in streams and rivers of Central Chile
<p>This repository encompasses the environmental concentrations of chemicals of emerging concern (CECs) occurring in surface water samples obtained from streams and rivers in Central Chile, specifically the River Aconcagua basin.</p>
Adopted Ranking Methodology for Emerging National Importance Technical Institutions: A Correlation Analysis and Dominance of Research Performance Indicators
<p>The article presents the research performance of newly established technical institutes in India. It gives an overview of NTU and NIRF ranking methodologies. This research would help institutions to check their performance and identify ways to strengthen their rank by producing more output with high-impact research work. The article provides appropriate input to the technical institutions under the study to set out practical and pedagogical approaches, and cross-institutional as well as international collaboration to achieve their research goals. The article gives rank to the technical institutes under the study based on their research performance using the NTU ranking methodology.</p>
Going across taxa in functional ecology: review and perspectives of an emerging field
<p>This dataset and all routines of analysis accompany the article "Going across taxa in functional ecology: review and perspectives of an emerging field", accepted in Functional Ecology. The dataset was obtained through a literature review in Web of Science (following the PRISMA principles for reviews and meta-analysis). We searched for studies using a trait-based approach in the study of multiple taxa. Then we applied quantitative analysis, based on the principles of ecological networks, to provide an overview of the use of multiple traits and taxa in functional ecology.</p>
Dataset of the publication : "Misfit layer compounds as ultra-tunable field effect transistors: from charge transfer control to emergent superconductivity"
<p>Dataset of the publication : "Misfit layer compounds as ultra-tunable field effect transistors: from charge transfer control to emergent superconductivity"</p>
Ketamine for Pain in the Emergency Department
ClinicalTrials.gov study NCT03896230. IPD Sharing: NO. Countries: 1. Publications: 21.
Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
ClinicalTrials.gov study NCT04148989. IPD Sharing: YES. Countries: 1. Publications: 1.
Cessation of Smoking Trial in the Emergency Department
ClinicalTrials.gov study NCT04854616. IPD Sharing: NO. Countries: 1. Publications: 3.
Shared Decision Making in the Emergency Department: Chest Pain Choice Trial
ClinicalTrials.gov study NCT01969240. IPD Sharing: YES. Countries: 1. Publications: 2.
Emergency Medicine Palliative Care Access
ClinicalTrials.gov study NCT03325985. IPD Sharing: YES. Countries: 1. Publications: 14.
PIMPmyHospital: a Mobile App to Improve Emergency Care Efficiency and Communication
ClinicalTrials.gov study NCT05203146. IPD Sharing: YES. Countries: 1. Publications: 2.
The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine
ClinicalTrials.gov study NCT02735343. IPD Sharing: YES. Countries: 1. Publications: 2.
Effect of Emergency Department Care Reorganization on Door-to-antibiotic Times for Sepsis (LDS SWARM)
ClinicalTrials.gov study NCT03226366. IPD Sharing: YES. Countries: 1. Publications: 1.
Pilot Study on Training Emerging Adults Skills in Navigating College
ClinicalTrials.gov study NCT05560425. IPD Sharing: YES. Countries: 1. Publications: 13.
Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial
ClinicalTrials.gov study NCT02643381. IPD Sharing: NO. Countries: 1. Publications: 2.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.