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Dataset results
356 results for “heritability”
Heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants
GEO Series GSE152570. Arabidopsis thaliana; Solanum lycopersicum. 54 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Mapping cis-regulatory elements in human excitatory and inhibitory neurons links psychiatric disease heritability and activity-regulated transcriptional programs [ATAC-seq]
GEO Series GSE196854. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A Non-Amyloid Prion Particle that Activates a Heritable Gene Expression Program.
GEO Series GSE138557. Saccharomyces cerevisiae. 8 samples. Type: Expression profiling by high throughput sequencing.
Multigenerational cell tracking of DNA replication and heritable DNA damage
GEO Series GSE255874. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
CRISPR/dCas9 DNA methylation editing is heritable during human haematopoiesis and can impair differentiation in vivo [methylation array]
GEO Series GSE222178. Homo sapiens. 9 samples. Type: Methylation profiling by genome tiling array.
Supplementary data : Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period
<p>BAM files from exome sequencing of 7 U2OS clonal cells used in the publication titled: Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period.</p> <p>Details of samples names are in 'sample details.txt'</p>
Data from: Superparasitism drives heritable symbiont epidemiology and host sex ratio in a wasp
Heritable microbial symbionts have profound impacts upon the biology of their arthropod hosts. Whilst our current understanding of the dynamics of these symbionts is typically cast within a framework of vertical transmission only, horizontal transmission has been observed in a number of cases. For instance, several symbionts can transmit horizontally when their parasitoid hosts share oviposition patches with uninfected conspecifics, a phenomenon called superparasitism. Despite this, horizontal transmission, and the host contact structures that facilitates it, have not been considered in heritable symbiont epidemiology. Here, we tested for the importance of host contact, and resulting horizontal transmission, for the epidemiology of a male-killing heritable symbiont (Arsenophonus nasoniae) in parasitoid wasp hosts. We observed that host contact through superparasitism is necessary for this symbiont's spread in populations of its primary host Nasonia vitripennis, such that when superparasitism rates are high, A. nasoniae almost reaches fixation, causes highly female biased population sex ratios and consequently causes local host extinction. We further tested if natural interspecific variation in superparasitism behaviours predicted symbiont dynamics among parasitoid species. We found that A. nasoniae was maintained in laboratory populations of a closely related set of Nasonia species, but declined in other, more distantly related pteromalid hosts. The natural proclivity of a species to superparasitise was the primary factor determining symbiont persistence. Our results thus indicate that host contact behaviour is a key factor for heritable microbe dynamics when horizontal transmission is possible, and that 'reproductive parasite' phenotypes, such as male-killing, may be of secondary importance in the dynamics of such symbiont infections.
Data from: Quantifying heritable variation in fitness-related traits of wild, farmed and hybrid Atlantic salmon families in a wild river environment
Farmed fish are typically genetically different from wild conspecifics. Escapees from fish farms may contribute one-way gene flow from farm to wild gene pools, which can depress population productivity, dilute local adaptations and disrupt coadapted gene complexes. Here, we reanalyse data from two experiments (McGinnity et al., 1997, 2003) where performance of Atlantic salmon (Salmo salar) progeny originating from experimental crosses between farm and wild parents (in three different cohorts) were measured in a natural stream under common garden conditions. Previous published analyses focussed on group-level differences but did not account for pedigree structure, as we do here using modern mixed-effect models. Offspring with one or two farm parents exhibited poorer survival in their first and second year of life compared with those with two wild parents and these group-level inferences were robust to excluding outlier families. Variation in performance among farm, hybrid and wild families was generally similar in magnitude. Farm offspring were generally larger at all life stages examined than wild offspring, but the differences were moderate (5–20%) and similar in magnitude in the wild versus hatchery environments. Quantitative genetic analyses conducted using a Bayesian framework revealed moderate heritability in juvenile fork length and mass and positive genetic correlations (>0.85) between these morphological traits. Our study confirms (using more rigorous statistical techniques) previous studies showing that offspring of wild fish invariably have higher fitness and contributes fresh insights into family-level variation in performance of farm, wild and hybrid Atlantic salmon families in the wild. It also adds to a small, but growing, number of studies that estimate key evolutionary parameters in wild salmonid populations. Such information is vital in modelling the impacts of introgression by escaped farm salmon.
Heritability and Genetics of Fat Taste
ClinicalTrials.gov study NCT02357316. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
ClinicalTrials.gov study NCT04005976. IPD Sharing: NO. Countries: 6. Publications: 0.
Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
ClinicalTrials.gov study NCT02413450. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes
ClinicalTrials.gov study NCT05534854. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Identification of Heritable CTEPH
ClinicalTrials.gov study NCT03579862. IPD Sharing: NO. Countries: 1. Publications: 0.
Heritability of Fatty Liver as Measured by MRI: a Cross Sectional Study of Twins and Family Members
ClinicalTrials.gov study NCT01643512. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Heritable changes in chromatin contacts linked to transgenerational obesity
GEO Series GSE218701. Mus musculus. 61 samples. Type: Other.
Dataset #2 for genome-wide analysis of heritable dog osteosarcoma in 3 breeds
GEO Series GSE51976. Canis lupus familiaris. 147 samples. Type: SNP genotyping by SNP array.
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [Bisulfite-Seq]
GEO Series GSE96612. Homo sapiens. 72 samples. Type: Methylation profiling by high throughput sequencing.
The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation
GEO Series GSE21291. Candida albicans. 7 samples. Type: Expression profiling by high throughput sequencing.
Data from: Heritability and genetic correlations of personality traits in a wild population of yellow-bellied marmots (Marmota flaviventris)
Open the record for dataset details and reuse information.
Data from: Superparasitism drives heritable symbiont epidemiology and host sex ratio in a wasp
Open the record for dataset details and reuse information.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.