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Fig. 6 in Eremophilane-type and xanthanolide-type sesquiterpenes from the aerial parts of Xanthium sibiricum and their anti-inflammatory activities

Fig. 6. Optimized geometry of 3 at the B3LYP/6–31G (d) level in methanol, and the comparison of the experimental and calculated ECD spectra of (6S,7S,9R,10R)-3a and (6R,7R,9S,10S)-3b.

opennotspecifiedApr 2023View details →
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Fig. 6 in Anti-inflammatory withanolides from the aerial parts of Physalis minima

Fig. 6. Molecular docking simulations of iNOS (A) and COX-2 (B) with bioactive compound 3 (colored by atom: carbon is cyan; nitrogen is blue; oxygen is red; hydrogen is gray; sulfur is orange). For clarity, only interacting residues are labeled. Hydrogen-bonding interactions are shown by dashes. These figures were created by PyMOL. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

opennotspecifiedOct 2022View details →
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Fig. 5 in Anti-inflammatory withanolides from the aerial parts of Physalis minima

Fig. 5. Effects of compound 3 on iNOS and COX-2 expression in LPS-induced RAW264.7 cells. RAW264.7 cells were pretreated with compound 3 (1, 3, and 10 μM) for 30 min and then stimulated with LPS for 24 h, cells were harvested, and total protein was extracted. Protein band intensity was normalized to β-actin and is expressed as fold difference relative to the LPS group (down). ###P <0.001, compared with control, ***P <0.001, compared with LPS group.

opennotspecifiedOct 2022View details →
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Fig. 4 in Bioactive prenylated phenolic compounds from the aerial parts of Glycyrrhiza uralensis

Fig. 4. The docking model and IC50 values of (1''R, 2''S)-1 and (1''S, 2''R)-1 against 3CLpro and PLpro. Each data point is displayed as the mean SD of three ± independent tests.

opennotspecifiedSep 2022View details →
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Fig. 3 in Bioactive prenylated phenolic compounds from the aerial parts of Glycyrrhiza uralensis

Fig. 3. The comparison of experimental and calculated ECD spectra of (1′′R, 2′′S)-1, (1′′S, 2′′R)-1, and 6.

opennotspecifiedSep 2022View details →
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Fig. 5 in Bioactive prenylated phenolic compounds from the aerial parts of Glycyrrhiza uralensis

Fig. 5. Bioactivity screening of compounds 1-26 [1a, (1''R, 2''S)-1; 1b, (1''S, 2''R)-1]. Each data point is displayed as the mean ± SD of three independent tests. ×: not tested.

opennotspecifiedSep 2022View details →
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Fig. 3 in Chemical constituents of Antidesma bunius aerial parts and the anti-AGEs activity of selected compounds

Fig. 3. Experimental CD spectra of 1 and 2; (B–F) Calculated and experimental ECD spectra of 2, 3, 4, 5, and 8.

opennotspecifiedOct 2022View details →
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FIGURE 1. A–H. Rohdea chloroxantha. A. Habitat. B. Aerial parts discarded after harvesting rhizomes. C. Stolons. D. Lateral bud. E, F & G. Cultivated plants. H. Blade. I in Rohdea chloroxantha (Asparagaceae), a new species from Southern Shaanxi, China

FIGURE 1. A–H. Rohdea chloroxantha. A. Habitat. B. Aerial parts discarded after harvesting rhizomes. C. Stolons. D. Lateral bud. E, F & G. Cultivated plants. H. Blade. I. Stolon of R. grandiflora. J. Stolon of R. pachynema.

opennotspecifiedAug 2023View details →
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Fig. 4 in Distribution of 5,6-dihydro-α-pyrones by electrospray ionization ion trap mass spectrometry in different aerial parts of Hyptis monticola

Fig. 4. UHPLC base peak ion chromatogram of CH2Cl2-soluble extract from leaves of Hyptis monticola. UHPLC-ESI-MS instrumental conditions: column C-18 (2.1 × 150 mm, 2 μm); mobile phase, gradient CH3CN:H2O; flow rate, 0.25 mL/min. Peaks assignments: tR 36.7 min =monticolide A (1); tR 27.6 min = monticolide B (2), tR 23.6 min = monticolide C (3); tR 29.6 min = monticolide D (4); tR 31.1 min = monticolide E (5); tR 19.1 min = monticolide F (6).

opennotspecifiedMay 2021View details →
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Fig. 6 in Distribution of 5,6-dihydro-α-pyrones by electrospray ionization ion trap mass spectrometry in different aerial parts of Hyptis monticola

Fig. 6. Average for the relative quantification of monticolides A-F (1–6) in different plant organs (n = 15, mean with SD).

opennotspecifiedMay 2021View details →
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Fig. 3 in Distribution of 5,6-dihydro-α-pyrones by electrospray ionization ion trap mass spectrometry in different aerial parts of Hyptis monticola

Fig. 3. Comparison of leaves extracts base peak chromatograms obtained with different solvents by UHPLC-ESI(+)-IT-MS. Analytical conditions: gradient mobile phase of CH3CN and 0.1% (v/v) aqueous formic acid; flow rate 0.25 mL/min; column C-18, 2.1 × 150 mm, 2 μm; sample concentration 0.5 mg/mL; mass spectrometry detection with ESI ionization in positive mode in the range of m/z 200 to 500. Peaks assignments: monticolides A-F, compounds 1–6.

opennotspecifiedMay 2021View details →
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Fig. 2 in Distribution of 5,6-dihydro-α-pyrones by electrospray ionization ion trap mass spectrometry in different aerial parts of Hyptis monticola

Fig. 2. Recycling HPLC chromatogram for the separation of diacetylated monticolides B (2) and C (3) from the CCC fractions 8–12 (see, Fig. S1). Chromatographic conditions: mobile phase CH3CN; flow rate, 4.7 mL/min; NH2 column, 19 × 150 mm, 10 μm, DAD detector (290 nm); sample concentration, 30 mg/mL.

opennotspecifiedMay 2021View details →
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Fig. 5 in Distribution of 5,6-dihydro-α-pyrones by electrospray ionization ion trap mass spectrometry in different aerial parts of Hyptis monticola

Fig. 5. PCA score plot of different extracts based on the relative abundances of total diagnostic ions for the distribution of monticolides A-F (1–6), which were registered by UHPLC-ESI(+)-IT-MS. Extracts prepared from flowers (HFL), leaves (HFO) and branches (HG). Codes were assigned according to the corresponding season and altitude as follows: HFL1, HFO1 and HG1-Spring collected at a low-altitude (1229 m) in 2013; HFL2, HFGO2 and HG2-winter collected at a low-altitude (1245 m) in 2017; HFL3, HFO3 and HG3-winter collected at a high-altitude (1310 m) in 2017; HFL4, HFO4 and HG4-summer collected at a low-altitude (1245 m) in 2018; and HFL5, HFO5 and HG5-summer collected at a high-altitude (1310 m) in 2018.

opennotspecifiedMay 2021View details →
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Fig. 5 in Guaianolide sesquiterpenes and benzoate esters from the aerial parts of Siegesbeckia orientalis L. and their xanthine oxidase inhibitory activity

Fig. 5. Predicted binding pose of compounds 1–12 and allopurinol into XO (A–M), active site of XO/oxipurinol (N, blue square), best binding pose of compounds 9 (pink) and 10 (blue) with XO (O). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

opennotspecifiedOct 2021View details →
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Fig. 4 in The racemic trimeric quinone and polycyclic quinones isolated from the aerial parts of Morinda umbellata L

Fig. 4. Experimental ECD spectra obtained in MeOH and calculated ECD spectra for isomers 1–4 (a–d, respectively).

opennotspecifiedMar 2021View details →
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Fig. 2 in The racemic trimeric quinone and polycyclic quinones isolated from the aerial parts of Morinda umbellata L

Fig. 2. Chiral HPLC-UV chromatogram of racemic 1–4 (a–d) using a Chiralpak AD-H column (4.6 mm × 250 mm, 5 μm); isocratic elution with n-hexane/EtOH (6:4, v/v), flow rate 1.0 mL/min, UV detection at 254 nm, temperature at 25 ◦ C.

opennotspecifiedMar 2021View details →
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Fig. 5 in Diverse alkaloids from the aerial parts of Aconitum carmichaelii and antiproliferative activity of costemline via inhibiting SIRT1/ROCK1/ P-STAT3 pathways

Fig. 5. The protein levels of ROCK1/SIRT1 and STAT3/P-STAT3 in colorectal cancer (CRC). (A) Western blot was used to analyze the expression or phosphorylation level of ROCK1, SIRT1 and STAT3 after HCT116 cells in the above groups were treated with 20 μM/40 μM compound 1 for 24 h. (B) At the protein level, the relative expression of SIRT1 and ROCK1/STAT3 signal was inhibited by compound 1 in HCT-116 cells. **p <0.01, ***p <0.001, ****p <0.0001 vs. control group.

opennotspecifiedMar 2023View details →
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Fig. 4. Compound 1 in Diverse alkaloids from the aerial parts of Aconitum carmichaelii and antiproliferative activity of costemline via inhibiting SIRT1/ROCK1/ P-STAT3 pathways

Fig. 4. Compound 1 inhibited invasion of HCT116 colon cancer cells in a transwell assay, which showed by representative images (A) and attached data (B). Cells were incubated with compound 1 (a) 0 μM, (b) 5 μM, (c) 10 μM for 24 h (original magnification, × 200). Quantitative data are presented as the mean ± standard deviation of 3 replicates, relative to the 0 μM control group. **p <0.01 vs. the 0 μM control group.

opennotspecifiedMar 2023View details →
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Fig. 5 in Study of two isoforms of lipoxygenase by kinetic assays, docking and molecular dynamics of a specialised metabolite isolated from the aerial portion of Lithrea caustica (Anacardiaceae) and its synthetic analogs

Fig. 5. Active site of molecular dynamics between 3-pentadecylcatechol (2) (A), (Z)-3-(pentadec-10′-enyl)-catechol (1) (B), and arachidonic acid with 5-hLOX and fluctuation of catechol distances during simulation time (10 ns).

opennotspecifiedJun 2020View details →
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Fig. 7 in Phytotoxic neo-clerodane diterpenoids from the aerial parts of Scutellaria barbata

Fig. 7. Phytotoxic effects of compound 2, 20, 21, 22, 25, 27, and glyphosate (positive control) on the growth of the roots and shoots of L. sativa seedlings at concentrations of 200, 100, 50, 25 μg/mL, respectively. (A) L. sativa shoot, (B) L. sativa root. (*) p <0.05, (**) p <0.01, and (***) p <0.001 versus the control group.

opennotspecifiedMar 2020View details →

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Allen Brain Atlas

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Annotated Behaviour and Observability Dataset (ABODe)

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DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

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International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

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OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

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Last verified 2026-04-29Open record