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341 results for “Neurodegeneration”

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geo20/100

Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease

GEO Series GSE236268. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2023View details →
geo20/100

Gene expression in a mouse model of Pantothenate Kinase-Associated Neurodegeneration

GEO Series GSE130705. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2020View details →
geo16/100

Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy

GEO Series GSE250277. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2024View details →
geo16/100

Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts

GEO Series GSE198526. Mus musculus. 48 samples. Type: Other.

openGEO-OpenJan 2023View details →
geo16/100

Angiotensin Converting Enzyme (ACE) expression in microglia reduces amyloid β deposition and neurodegeneration by increasing SYK signaling and endolysosomal trafficking.

GEO Series GSE288410. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenMar 2025View details →
geo16/100

Extracellular matrix glycation epigenetically regulates brain aging and neurodegeneration in the in vitro aged neurovascular model

GEO Series GSE278799. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo16/100

CD200R1 loss in CNS-associated macrophages triggers T cell-driven neurodegeneration in Parkinson’s disease

GEO Series GSE304505. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo16/100

Microglial 25-hydroxycholesterol mediates neuroinflammation and neurodegeneration in a tauopathy mouse model.

GEO Series GSE242896. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo16/100

TIA1-mediated stress granules promote the neurodegeneration of motor neurons through sequestrating mRNA of heat shock protein HSP70 family in C9orf72-poly-GA mice

GEO Series GSE297313. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2025View details →
geo16/100

Z-RNA drives Tau-mediated neurodegeneration of Alzheimer’s disease [RIP-Seq]

GEO Series GSE248069. Mus musculus. 3 samples. Type: Other.

openGEO-OpenNov 2023View details →
geo16/100

Reversing lysosome-mTORC1-ribosome axis dysregulations to mitigate C9FTD/ALS neurodegeneration [bulk RNA-Seq]

GEO Series GSE206665. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo16/100

Immune Tolerance to HSP60 Attenuates Neurodegeneration in Glaucoma

GEO Series GSE268936. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo16/100

Immune Receptor Lag3 Deletion Alleviates Neurodegeneration Phenotypes in a Mouse Model of Alzheimer’s Disease

GEO Series GSE307127. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

Reduction in olfactory ability in aging Mitf mutant mice without evidence of neurodegeneration

GEO Series GSE277734. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2024View details →
geo16/100

Transcriptional Profile of Microglia in Neurodegeneration

GEO Series GSE92550. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2020View details →
geo16/100

NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis

GEO Series GSE144294. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2020View details →
geo16/100

Zinc finger protein 184 prevents α-synuclein preformed fibril-mediated neurodegeneration through the interleukin enhancer binding factor 3-microRNA-7 pathway

GEO Series GSE282345. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo16/100

Z-RNA drives Tau-mediated neurodegeneration of Alzheimer’s disease

GEO Series GSE248070. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenNov 2023View details →
geo16/100

CD8 T cells are primed by cDC1 and exacerbate tau-mediated neurodegeneration

GEO Series GSE279315. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

Neuronal accumulation of peroxidated lipids promotes demyelination and neurodegeneration though the activation of the microglial NLRP3 inflammasome

GEO Series GSE183483. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record