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Dataset results
646 results for “Pseudomonas aeruginosa”
The repressor C protein, Pf4r, controls superinfection of Pseudomonas aeruginosa PAO1 by the Pf4 filamentous phage and regulates host gene expression
GEO Series GSE154459. Pseudomonas aeruginosa PAO1. 11 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Establishment and characterization of persistent Pseudomonas aeruginosa infections in air-liquid interface cultures of human airway epithelial cells
GEO Series GSE262433. Pseudomonas aeruginosa; Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Chromatin Immunoprecipitation of HA-tagged PA14_69770 and RpoA in Pseudomonas aeruginosa UCBPP-PA14
GEO Series GSE66179. Pseudomonas aeruginosa. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genetic and transcriptomic characteristics of RhlR-dependent quorum sensing in cystic fibrosis isolates of Pseudomonas aeruginosa: isolate E104
GEO Series GSE198534. Pseudomonas aeruginosa. 6 samples. Type: Expression profiling by high throughput sequencing.
Functional characterization of TetR-like transcriptional regulator PA3973 from Pseudomonas aeruginosa [ChIP-seq]
GEO Series GSE211769. Pseudomonas aeruginosa. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Contribution of Veillonella parvula to Pseudomonas aeruginosa mediated pathogenicity in a murine tumor model system
GEO Series GSE58388. Veillonella parvula DSM 2008; Mus musculus; Pseudomonas aeruginosa PA14. 12 samples. Type: Expression profiling by high throughput sequencing.
Identification of the alternative sigma factor SigX regulon and its implications for Pseudomonas aeruginosa pathogenicity
GEO Series GSE50937. Pseudomonas aeruginosa UCBPP-PA14. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Global trends of Pseudomonas aeruginosa biofilm research in the past two decades: A bibliometric study
<p>This dataset was used to conduct bibliometric and visualised analyses on research relating to Pseudomonas aeruginosa biofilms over the past two decades.</p>
Data from: Enhancing the steroid sulfatase activity of the arylsulfatase from Pseudomonas aeruginosa
Steroidal sulfate esters play a central role in many physiological processes. They serve as the reservoir for endogenous sex hormones and form a significant fraction of the steroid metabolite pool. The analysis of steroid sulfates is thus essential in fields such as medical science and sports drug testing. Although the direct detection of steroid sulfates can be readily achieved using liquid chromatography-mass spectrometry, many analytical approaches, including gas chromatography-mass spectrometry, are hampered due to the lack of suitable enzymatic or chemical methods for sulfate ester hydrolysis prior to analysis. Enhanced methods of steroid sulfate hydrolysis would expand analytical possibilities for the study of these widely occurring metabolites. The arylsulfatase from Pseudomonas aeruginosa (PaS) is a purified enzyme capable of hydrolysing steroid sulfates. However, this enzyme requires improvement to hydrolytic activity and substrate scope in order to be useful in analytical applications. These improvements were sought by applying semi-rational design to mutate amino acid residues neighbouring the enzyme active site. Mutagenesis was implemented on both single and multiple residue sites. Screening by UPLC-MS was performed to test the steroid sulfate hydrolysis activity of these mutant libraries against testosterone sulfate. This approach revealed the steroid sulfate binding pocket and resulted in three mutants that showed an improvement in catalytic efficiency (Vmax/KM) of more than 150 times that of wild-type PaS. The substrate scope of PaS was expanded and a modest increase in thermostability was observed. Finally, molecular dynamics simulations of enzyme-substrate complexes were used to provide qualitative insight into the structural origin of the observed effects.
Figure 3 from: Dorri K, Modaresi F, Shakibaie MR, Moazamian E (2022) Effect of gold nanoparticles on the expression of efflux pump mexA and mexB genes of Pseudomonas aeruginosa strains by Quantitative real-time PCR. Pharmacia 69(1): 125-133. https://doi.org/10.3897/pharmacia.69.e77608
Figure 3 Susceptibility of Pseudomonas aeruginosa isolates to different antibiotics.
Figure 2 from: Dorri K, Modaresi F, Shakibaie MR, Moazamian E (2022) Effect of gold nanoparticles on the expression of efflux pump mexA and mexB genes of Pseudomonas aeruginosa strains by Quantitative real-time PCR. Pharmacia 69(1): 125-133. https://doi.org/10.3897/pharmacia.69.e77608
Figure 2 Distribution of clinical isolates of Pseudomonas aeruginosa in the studied hospitals.
Figure 19 from: Dorri K, Modaresi F, Shakibaie MR, Moazamian E (2022) Effect of gold nanoparticles on the expression of efflux pump mexA and mexB genes of Pseudomonas aeruginosa strains by Quantitative real-time PCR. Pharmacia 69(1): 125-133. https://doi.org/10.3897/pharmacia.69.e77608
Figure 19 The characteristics of the gold nanoparticles used.
Figure 13 from: Dorri K, Modaresi F, Shakibaie MR, Moazamian E (2022) Effect of gold nanoparticles on the expression of efflux pump mexA and mexB genes of Pseudomonas aeruginosa strains by Quantitative real-time PCR. Pharmacia 69(1): 125-133. https://doi.org/10.3897/pharmacia.69.e77608
Figure 13 Results of MexA gene amplification curve in Real Time PCR by cycle.
Figure 1 from: Dorri K, Modaresi F, Shakibaie MR, Moazamian E (2022) Effect of gold nanoparticles on the expression of efflux pump mexA and mexB genes of Pseudomonas aeruginosa strains by Quantitative real-time PCR. Pharmacia 69(1): 125-133. https://doi.org/10.3897/pharmacia.69.e77608
Figure 1 Frequency of clinical samples.
The Histone H1-like protein AlgP facilitates even spacing of polyphosphate granules in Pseudomonas aeruginosa, Dataset B
<p>Raw Data, Part 2</p>
Acyl-CoA dehydrogenases involved in fatty acid degradation of Pseudomonas aeruginosa: substrate specificity
<p>MD trajectories raw data </p>
[PART 3] How to fit a round peg in a square hole: Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity.
<p>Metadynamics data for the PaFADE1</p> <p>1320- PaFadE1 8PNS noCoA +FAD + G129M A295E - metadynamics, 10A3 OPLS4 T3P<br>1321- PaFadE1 8PNS noCoA +FAD WT - metadynamics, 10A3 OPLS4 T3P</p>
[PART 2] How to fit a round peg in a square hole: Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity.
<p>Classical unbiased molecular dynamics dataset generated with Maestro 2023.4</p> <p>1320- PaFadE1 8PNS noCoA +FAD + G129M A295E, 10A3 OPLS4 T3P<br>1321- PaFadE1 8PNS noCoA +FAD WT, 10A3 OPLS4 T3P</p>
Dataset for In silico study of novel inhibitors to Pseudomonas aeruginosa Lipase enzyme
<p>Tarballs of docked structures, MD trajectories and BPMD simulations of novel inhibitors targeting the P. aeruginosa Lipase enzyme. The LIPASE.rar file contains all data for docked structures, BPMD simulations and replica number 3 of the MD simulations. MD simulation data from replicas 1 and 2 are available in the other two rar files. </p>
Phenotypic Profile and Molecular Mechanism of Resistance in Carbapenemase-producing Enterobacterales and Pseudomonas Aeruginosa Isolates From Brazilian Hospitals: Implications for the Introduction of
ClinicalTrials.gov study NCT05285046. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.