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697 results for “Staphylococcus Aureus”
The Identification of Genetic Factors Influencing Susceptibility to Staphylococcus aureus Infection in mice susceptible and resistant to S. aureus infection
GEO Series GSE23584. Mus musculus. 36 samples. Type: Expression profiling by array.
Staphylococcus aureus-derived factors promote Th9 cell polarization and strongly enhance a transcriptional program associated with inflammation and allergy
GEO Series GSE206288. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Staphylococcus aureus lipoteichoic acid-stimulated undifferentiated and neutrophil-like differentiated HL-60 cells
GEO Series GSE239859. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Bacteria-host transcriptional response during endothelial invasion by Staphylococcus aureus
GEO Series GSE151135. Homo sapiens; Staphylococcus aureus. 12 samples. Type: Expression profiling by high throughput sequencing.
Mode of action studies of the novel bisquaternary bisnaphthalimide MT02 against Staphylococcus aureus
GEO Series GSE23077. Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus; Staphylococcus aureus subsp. aureus NCTC 8325; Staphylococcus aureus subsp. aureus N315; Staphylococcus aureus subsp. aureus USA300; Staphylococcus aureus subsp. aureus COL; Staphylococcus aureus subsp. aureus MW2; Staphylococcus aureus subsp. aureus Mu50; Staphylococcus aureus subsp. aureus MSSA476. 2 samples. Type: Expression profiling by array.
Tea tree oil induced transcriptional alterations in Staphylococcus aureus
GEO Series GSE31554. Staphylococcus aureus. 4 samples. Type: Expression profiling by array.
Daptomycin-Resistance Mechanisms in Clinically-Derived Staphylococcus aureus Strains Assessed by a Combined Transcriptomics and Proteomics Approach
GEO Series GSE28632. Staphylococcus aureus subsp. aureus NCTC 8325; Staphylococcus aureus subsp. aureus COL; Staphylococcus aureus subsp. aureus N315; Staphylococcus aureus subsp. aureus USA300; Staphylococcus aureus; Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus subsp. aureus MSSA476; Staphylococcus aureus subsp. aureus Mu50; Staphylococcus aureus subsp. aureus MW2. 6 samples. Type: Expression profiling by array.
Unveiling co-infection in cystic fibrosis airways: Transcriptomic analysis of Pseudomonas aeruginosa and Staphylococcus aureus dual-species biofilms
GEO Series GSE195909. Pseudomonas aeruginosa; Staphylococcus aureus. 6 samples. Type: Expression profiling by high throughput sequencing.
The functional small RNA interactome reveals targets for the vancomycin-responsive sRNA RsaOI in vancomycin tolerant Staphylococcus aureus [RNase III-CLASH]
GEO Series GSE254532. Staphylococcus aureus subsp. aureus str. JKD6008. 10 samples. Type: Other.
The functional small RNA interactome reveals targets for the vancomycin-responsive sRNA RsaOI in vancomycin tolerant Staphylococcus aureus [RNA-seq]
GEO Series GSE254530. Staphylococcus aureus subsp. aureus str. JKD6008. 6 samples. Type: Expression profiling by high throughput sequencing.
Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Staphylococcus aureus BPH2986
GEO Series GSE152833. Staphylococcus aureus. 12 samples. Type: Expression profiling by high throughput sequencing.
High throughput transcriptomics analysis of ovine mammary epithelial cells stimulated with Staphylococcus aureus in vitro
GEO Series GSE295455. Ovis aries. 6 samples. Type: Expression profiling by high throughput sequencing.
MazF toxin causes alterations in Staphylococcus aureus transcriptome, translatome and proteome that underlie bacterial dormancy
GEO Series GSE155036. Staphylococcus aureus. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
The small RNA SprY controls RNAIII function and affects Staphylococcus aureus virulence
GEO Series GSE166499. Staphylococcus aureus. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Biphasic effects of pleiotropic cytokine IL-27 during Staphylococcus aureus implant-associated osteomyelitis
GEO Series GSE168896. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Staphylococcus aureus walKR mutants (TPS3130 and TPS3190) vs. parent strains (JKD6009 and JKD6004)
GEO Series GSE29157. Staphylococcus aureus. 6 samples. Type: Expression profiling by array.
Data from: Lambda interferon restructures the nasal microbiome and increases susceptibility to Staphylococcus aureus superinfection
Much of the morbidity and mortality associated with influenza virus respiratory infection is due to bacterial coinfection with pathogens that colonize the upper respiratory tract such as methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae. A major component of the immune response to influenza virus is the production of type I and III interferons. Here we show that the immune response to infection with influenza virus causes an increase and restructuring of the upper respiratory microbiota in wild-type (WT) mice but not in Il28r−/− mutant mice lacking the receptor for type III interferon. Mice lacking the IL-28 receptor fail to induce STAT1 phosphorylation and expression of its regulator, SOCS1. Il28r−/− mutant mice have increased expression of interleukin-22 (IL-22), as well as Ngal and RegIIIγ, in the nasal cavity, the source of organisms that would be aspirated to cause pneumonia. Proteomic analysis reveals changes in several cytoskeletal proteins that contribute to barrier function in the nasal epithelium that may contribute to the effects of IL-28 signaling on the microbiota. The importance of the effects of IL-28 signaling in the pathogenesis of MRSA pneumonia after influenza virus infection was confirmed by showing that WT mice nasally colonized before or after influenza virus infection had significantly higher levels of infection in the upper airways, as well as significantly greater susceptibility to MRSA pneumonia than Il28r−/− mutant mice did. Our results suggest that activation of the type III interferon in response to influenza virus infection has a major effect in expanding the upper airway microbiome and increasing susceptibility to lower respiratory tract infection.
Data from: Biofilm-associated multidrug-resistant and methicillin-resistant staphylococcus aureus infections in children
<p><strong>Introduction: </strong>The ability of <em>Staphylococcus aureus</em> to form biofilms—architectural complexes that cause chronic and recalcitrant infections—along with its notorious variant, methicillin-resistant <em>S. aureus</em> (MRSA), leads to multidrug-resistant (MDR) infections that are challenging to treat with antibiotics. This cross-sectional study investigated the prevalence of <em>S. aureus </em>infections in children (<17 years) and characterized the antibiograms of MDR, MRSA, and biofilm-forming strains, along with their coexistence.</p> <p><strong>Methods:</strong> <em>S. aureus</em> strains were isolated and identified from clinical samples and tested for antibiograms following standard microbiology guidelines. MDR strains were non-susceptible to at least one agent in three antimicrobial categories, whereas MRSA strains were cefoxitin-resistant. The gold-standard microtiter plate method was used to detect biofilms. Statistical analyses were performed using SPSS version 17.0.</p> <p><strong>Results:</strong> <em>S. aureus</em> was detected in 9.02% of 543 samples, primarily from pus (79.59%, 39/49). Children aged 1 to <3 years most commonly contracted infections (30.61%, 15/49), and males (67.35%, 33/49) had twice as many infections as females (32.65%, 16/49). As high as 84.69% (83/98) of strains were penicillin-resistant, while 18.37% (27/147) were aminoglycoside-resistant. MDR accounted for 79.59% (39/49) of all <em>S. aureus</em> infections, while MRSA and biofilm-formers accounted for 67.35% (33/49) and 24.49% (12/49), respectively. Fluoroquinolone resistance in non-(MDR-MRSA-biofilm-formers), MDR-MRSA, MDR-biofilm-formers, and MRSA-biofilm-formers was 31.25%, 46.77%, 58.33%, and 60%, respectively, while aminoglycoside resistance was 0%, 32.26%, 50.0%, and 45.0%, and penicillin resistance was 87.50%, 85.48%, 100.0%, and 100.0%.</p> <p><strong>Conclusion:</strong> <em>S. aureus</em>, mostly MDR and MRSA, caused four-fifths of infections in children. Compared to MDR-MRSA and non-(MDR-MRSA-biofilm-formers), MDR-biofilm-formers and MRSA-biofilm-formers triggered higher levels of antimicrobial resistance.</p>
Figure 1 from: Satria D, Sofyanti E, Wulandari P, Fajarini, Pakpahan SD, Limbong SA (2022) Antibacterial activity of Medan Butterfly pea (Clitoria ternatea L.) corolla extract against Streptococcus mutans ATCC®25175™ and Staphylococcus aureus ATCC®6538™. Pharmacia 69(1): 195-202. https://doi.org/10.3897/pharmacia.69.e77076
Figure 1 Photographic image of Medan Butterfly Pea.
Figure 2 in Metal nanoparticles produced by plants with antibacterial properties against Staphylococcus aureus
Figure 2. Various antibacterial mechanisms of metal nanoparticles against Staphylococcus aureus.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.