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897
datasets available to search
ShareScore release 0.9.0
Dataset results
897 results for “Therapeutic targets”
HDAC5, an early osimertinib-responsive gene, is a novel therapeutic target for the drug resistance in EGFR-mutant lung adenocarcinoma cells.
GEO Series GSE283536. Homo sapiens. 4 samples. Type: Expression profiling by array.
PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination [invitro]
GEO Series GSE280579. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
RNA m1A methyltransferase TRMT61A induces MAPK/ERK signaling and is a therapeutic target in colorectal cancer [Ribo-Seq]
GEO Series GSE274079. Homo sapiens. 4 samples. Type: Other.
The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer
GEO Series GSE224911. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Other.
IL-11 is a therapeutic target in idiopathic pulmonary fibrosis
GEO Series GSE130983. Mus musculus; Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing.
A Blood-based Transcriptomic Signature Stratifies Severe Crohn's disease and Defines Potentially Targetable Therapeutic Pathways
GEO Series GSE217352. Homo sapiens. 265 samples. Type: Expression profiling by high throughput sequencing.
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
GEO Series GSE229648. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Targeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma
GEO Series GSE144288. Homo sapiens; Mus musculus. 85 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Targeting AXL can effectively inhibit c-Met-induced therapeutic resistance in renal cancer
GEO Series GSE296078. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Integrated Genetic and Proteomic Analysis Identifies PLK1 as a Candidate Therapeutic Target for SETD2-Deficient Clear Cell Renal Cell Carcinoma
GEO Series GSE107391. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages
GEO Series GSE228765. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Profibrotic monocyte-derived alveolar macrophages as a biomarker and therapeutic target in systemic sclerosis-associated interstitial lung disease [Northwestern]
GEO Series GSE303859. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Characterization and therapeutic targeting of the miR-21/PPP2R2A/ERK molecular circuit in bladder cancer
GEO Series GSE97782. Homo sapiens. 28 samples. Type: Expression profiling by array.
ZMYND8 is potential selective therapeutic target for modulating the IRF8/MYC transcriptional networks in AML
GEO Series GSE157636. Homo sapiens. 105 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Transcription factor ZNF263 enhances EGFR-targeted therapeutic response and reduces residual disease in lung adenocarcinoma [RNAseq]
GEO Series GSE253741. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
PARP-1 as a potential therapeutic target in ERα-positive endocrine therapy-resistant breast cancer
GEO Series GSE277883. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target
GEO Series GSE276445. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
BCL-xL as a therapeutic target in cetuximab-refractory colorectal cancer
GEO Series GSE299943. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Identification of DEK as a potential therapeutic target for Neuroendocrine prostate cancer
GEO Series GSE61214. Homo sapiens. 4 samples. Type: Expression profiling by array.
High-Throughput mRNA Sequencing Reveals Potential Therapeutic Targets of Febuxostat in Secondary Injury After Intracerebral Hemorrhage
GEO Series GSE193076. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.