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334 results for “temporal variation”
Data from: Temporal variation in antibiotic environments slows down resistance evolution in pathogenic Pseudomonas aeruginosa
Antibiotic resistance is a growing concern to public health. New treatment strategies may alleviate the situation by slowing down the evolution of resistance. Here, we evaluated sequential treatment protocols using two fully independent laboratory-controlled evolution experiments with the human pathogen Pseudomonas aeruginosa PA14 and two pairs of clinically relevant antibiotics (doripenem/ciprofloxacin and cefsulodin/gentamicin). Our results consistently show that the sequential application of two antibiotics decelerates resistance evolution relative to monotherapy. Sequential treatment enhanced population extinction although we applied antibiotics at sub-lethal dosage. In both experiments, we identified an order-effect of the antibiotics used in the sequential protocol, leading to significant variation in the long-term efficacy of the tested protocols. These variations appear to be caused by asymmetric evolutionary constraints, whereby adaptation to one drug slowed down adaptation to the other drug, but not vice versa. An understanding of such asymmetric constraints may help future development of evolutionary robust treatments against infectious disease.
Figure 2 in Temporal variation and structure of macro-epifauna associated with macrophytes in the Bizerte lagoon (Tunisia, SW Mediterranean Sea)
Figure 2. Monthly variations of environmental factors at Menzel Jemil during sampling periods.
Figure 2 in Diversity and temporal variations of the leafhopper fauna (Cicadellidae, Auchenorrhyncha, Hemiptera) in two ecological zones of Egypt
Figure 2. Dendrogram from the cluster analysis of cicadellid communities at the six study sites.
Figure 1 in Diversity and temporal variations of the leafhopper fauna (Cicadellidae, Auchenorrhyncha, Hemiptera) in two ecological zones of Egypt
Figure 1. Map of Egypt showing the study sites.
Fig. 1 in Temporal and ontogenetic variations in feeding habits of Hollandichthys multifasciatus (Teleostei: Characidae) in coastal Atlantic rainforest streams, southern Brazil
Fig. 1. Northern coast of Santa Catarina State (southern Brazil), showing the city of São Francisco do Sul and the location of the study sites (1, 2).
Grasshopper genome reveals long-term conservation of the X chromosome and temporal variation in X chromosome evolution
<p>We present the first chromosome-level genome assembly of the grasshopper, <em>Locusta migratoria</em>, one of the largest insect genomes. We use coverage differences between females (XX) and males (X0) to identify the X chromosome gene content, and find that the X chromosome shows both complete dosage compensation in somatic tissues and an underrepresentation of testes-expressed genes. Remarkably, X-linked gene content from <em>L. migratoria </em>is highly conserved across four insect orders, namely Orthoptera, Hemiptera, Coleoptera and Diptera, and the 800 Mb grasshopper X chromosome is homologous to the fly ancestral X chromosome despite 400 million years of divergence, suggesting either repeated origin of sex chromosomes with highly similar gene content, or long-term conservation of the X chromosome. We use this broad conservation of the X chromosome to test for temporal dynamics to Fast-X evolution, and find evidence of a recent burst evolution for new X-linked genes in contrast to slow evolution of X-conserved genes. Additionally, our results reveal the X chromosome represents a hotspot for adaptive protein evolution related migration and the locust swarming phenotype. Overall, our results reveal a remarkable case of conservation and adaptation on the X chromosome.</p>
Fig. 1 in Temporal variations in the diversity of true crabs (Crustacea: Brachyura) in the St Lucia Estuary, South Africa
Fig. 1. Maps of the St Lucia Estuary: (a) expansion of the estuary and mouth region (adapted from Carrasco et al. 2010); (b) highlighting sampling sites and sources of freshwater inflow via tributary rivers.
Identifying non-synergestic effect of temporal variations of margin and dependence between extremes on the projected risk of compound dry-hot events in Yellow River, China
<p>Site-based daily precipitation and temperature data in China</p>
CT Temporal Bone Anatomical Variations
ClinicalTrials.gov study NCT06597877. IPD Sharing: NO. Countries: 0. Publications: 5.
Data from: Similarity in temporal variation in sex-biased dispersal over short and long distances in the dark-eyed junco, Junco hyemalis
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Data from: Temporal variation in habitat selection breaks the catch-22 of spatially contrasting predation risk from multiple predators
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Data from: Metabarcoding reveals environmental factors influencing spatio-temporal variation in pelagic micro-eukaryotes
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Spatial and temporal genetic variation in Ethiopian barley (Hordeum vulgare L.) landraces as revealed by simple sequence repeat (SSR) markers
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What doesn’t kill you can make you stronger: variation in plasticity in response to early temporally heterogeneous hydrological experience
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Data from: Temporal intraspecific trait variability drives responses of functional diversity to inter-annual aridity variation in grasslands
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Data from: Temporal variation favors the evolution of generalists in experimental populations of Drosophila melanogaster
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Data from: Temporal variation in antibiotic environments slows down resistance evolution in pathogenic Pseudomonas aeruginosa
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Data from: Heritability, evolvability, phenotypic plasticity and temporal variation in sperm-competition success of Drosophila melanogaster
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Spatial and temporal variation in prey colour patterns for background-matching across a continuous heterogeneous environment
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Data from: Using adaptive traits to consider potential consequences of temporal variation in selection: male guppy colour through time and space
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.