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3,241
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Dataset results
3,241 results for “alcoholism”
Animal model of acute-on-chronic alcoholic liver injury [DDC study]
GEO Series GSE119953. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges.
GEO Series GSE172166. Homo sapiens. 32 samples. Type: Non-coding RNA profiling by array.
Multicellular liver organoid model for recapitulating hepatitis C virus infection and non-alcoholic fatty liver disease progression
GEO Series GSE229609. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Chronic Alcohol Consumption Alters micro-RNA Radiation Responses in the Mouse Liver
GEO Series GSE79186. Homo sapiens; Mus musculus; Rattus norvegicus. 12 samples. Type: Non-coding RNA profiling by array.
Transcriptome sequencing of pancreas and adipose tissues in obesity-related alcohol-induced acute pancreatitis
GEO Series GSE200061. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
CCSER1 transcriptomic analysis reveals a role in neurodevelopmental phenotypes and alcohol response.
GEO Series GSE282155. Danio rerio. 29 samples. Type: Expression profiling by high throughput sequencing.
Comparison of whole brain expression data between selectively bred P and NP, alcohol naïve rats
GEO Series GSE15764. Rattus norvegicus. 7 samples. Type: Expression profiling by array.
Single-Cell RNA Sequencing Reveals Distinct Cellular and Molecular Features of Steroid-Induced Osteonecrosis of the Femoral Head Compared to Alcohol-Induced Osteonecrosis and Hip Osteoarthritis
GEO Series GSE316957. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Perturbed liver gene zonation in a mouse model of non-alcoholic steatohepatitis
GEO Series GSE248077. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing; Other.
A Long Non-Coding RNA (Lrap) Modulates Brain Gene Expression and Levels of Alcohol Consumption in Rats
GEO Series GSE155709. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Gene expression profile of non-alcoholic fatty liver (NAFLD) liver at the single-cell level
GEO Series GSE270583. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Hepatic enhancer signature and regulatory network of non-alcoholic steatohepatitis (NASH) resistance in humans with obesity [leChRO-seq]
GEO Series GSE182129. Homo sapiens. 18 samples. Type: Other.
Comparative mRNA Profile Analysis from NAc of Adolescent Male Mice after Binge-Like Alcohol Exposure Eliciting Deficits in Context Fear Extinction Learning.
GEO Series GSE290254. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Large Annotated Ultrasound Dataset of Non-Alcoholic Fatty Liver from Saudi Hospitals for Analysis and Applications
<p><strong>Large Annotated Ultrasound Dataset for Non-Alcoholic Fatty Liver Disease (NAFLD)</strong></p> <p>This dataset is a valuable resource for researchers and developers working on AI-assisted diagnosis and staging of Non-Alcoholic Fatty Liver Disease (NAFLD). It comprises a substantial collection of 10,352 high-resolution ultrasound images obtained from 384 patients at two major Saudi hospitals.</p> <p><strong>Key features of the dataset:</strong></p> <ul> <li><strong>Size and diversity:</strong> A large dataset with images from a diverse patient population, capturing a wide spectrum of NAFLD severity.</li> <li><strong>Detailed annotations:</strong> Each image is meticulously annotated with NAFLD Activity Score (NAS) fibrosis staging and steatosis grading, based on corresponding liver biopsy results.</li> <li><strong>Standardization:</strong> Images undergo rigorous pre-processing, including size standardization and quality control, ensuring consistency and reliability.</li> <li><strong>Technical validation:</strong> Inter-rater reliability and image quality preservation are rigorously assessed.</li> </ul> <p><strong>Potential applications:</strong></p> <ul> <li>Development and evaluation of AI algorithms for accurate NAFLD diagnosis and staging.</li> <li>Research on the correlation between ultrasound image features and NAFLD progression.</li> <li>Support for the development of computer-aided diagnostic tools for clinicians.</li> </ul> <p>By providing a comprehensive and well-annotated dataset, this resource aims to accelerate research and improve patient outcomes in NAFLD management.</p>
Somatosensory profiling of patients undergoing alcohol withdrawal: do neuropathic pain and sensory loss represent a problem?
<p>Chronic heavy alcohol use is known to cause neurological complications such as peripheral neuropathy. Concerning the pathophysiology, few sural nerve and skin biopsies studies showed that small fibers might be selectively vulnerable to degeneration in alcohol-related peripheral neuropathy. Pain has rarely been properly evaluated in this pathology. The aim of the present study was to assess pain intensity, potential neuropathic characteristics as well as the functionality of both small and large nerve sensitive fibers.</p> <p>In this observational study, twenty-seven consecutive adult patients, hospitalized for alcohol withdrawal and 13 healthy controls were recruited. All the participants underwent a quantitative sensory testing (QST) according to the standardized protocol of the German Research Network Neuropathic Pain, a neurological examination and filled standardized questionnaires assessing alcohol consumption and dependence as well as pain characteristics and psychological comorbidities.</p> <p>Half of the patients reported pain. Yet the intensity was weak, leading to a low interference with daily life, and the characteristics did not support a neuropathic component. A functional impairment of small nerve fibers was frequently described, with thermal hypoesthesia observed in 52% of the patients. Patients with a higher alcohol consumption over the last 2 years showed a greater impairment of small fiber function. </p>
Role of CCL2 in Alcoholic Liver Diseases
ClinicalTrials.gov study NCT01128010. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Antiglutamate Anticonvulsants in the Treatment of Alcohol Withdrawal Syndrome
ClinicalTrials.gov study NCT00241995. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Altered molecular signaling pathways in the hippocampus of rhesus monkeys following chronic alcohol use
GEO Series GSE297855. Macaca mulatta. 12 samples. Type: Expression profiling by high throughput sequencing.
Effect of depletion of Smarca4 on gene expression of alcoholic liver disease
GEO Series GSE207090. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of hepatic gene expression in patients with non-alcoholic steatohepatitis (NASH) before and after 1 year supplementation with n-3 polyunsaturated fatty acids (PUFA) from fishoil
GEO Series GSE96971. Homo sapiens. 18 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.