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Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Microglia-astrocyte interplay mitigates Aβ toxicity in a novel human 3D neurosphere model of Alzheimer’s Disease
GEO Series GSE272186. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
APP levels mediate beta-amyloid but not tau-related aspects of Alzheimer’s disease in a Down syndrome model of cortical neurogenesis.
GEO Series GSE100680. Homo sapiens. 34 samples. Type: Expression profiling by array.
Cell-matrix interactions control biliary organoids polarity,architecture and differentiation and can be exploited to improve modelling of biliary diseases.
GEO Series GSE204960. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease
GEO Series GSE117592. Mus musculus. 16 samples. Type: Methylation profiling by high throughput sequencing.
A Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome
GEO Series GSE163106. Saccharomyces cerevisiae. 6 samples. Type: Expression profiling by high throughput sequencing.
Aberrant neurodevelopment in human iPS cell-derived neural organoid model of Alexander disease
GEO Series GSE261157. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Transplantation of wild-type hematopoietic stem and progenitor cells rescue Alzheimer’s disease in a mouse model and highlights the central role of microglia in disease pathogenesis
GEO Series GSE217885. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of Inflammatory Bowel Disease
GEO Series GSE181253. Mus musculus. 24 samples. Type: Other.
In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons
GEO Series GSE152867. Mus musculus; Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiling in knock-in mouse models of Huntington's disease [Cortex_mRNA]
GEO Series GSE65770. Mus musculus. 168 samples. Type: Expression profiling by high throughput sequencing.
Global gene expression profiling in PPAR-γ agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease
GEO Series GSE35167. Rattus norvegicus. 2 samples. Type: Expression profiling by array.
Single-cell transcriptomics unveils molecular signatures of neuronal vulnerability in a mouse model of prion disease that overlap with Alzheimer’s disease
GEO Series GSE249382. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Multi-omics characterization of inflammatory bowel disease induced hyperplasia/dysplasia in the Rag2-/- / Il10-/- mouse model
GEO Series GSE163038. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Region specific astrocyte response to mutant GFAP in Alexander disease model mice during postnatal development.
GEO Series GSE198817. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Spatially-patterned and functional kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
GEO Series GSE272707. Homo sapiens. 4 samples. Type: Other.
MicroRNA alterations in a mouse model of prion disease
GEO Series GSE146013. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
RNA-Targeting CRISPR/CasRx System Relieves Disease Symptoms in Huntington's Disease Models
GEO Series GSE248873. Sus scrofa; Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Insights into dentatorubral-pallidoluysian atrophy from a new Drosophila model of disease
GEO Series GSE289036. Drosophila melanogaster. 29 samples. Type: Expression profiling by high throughput sequencing.
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease.
GEO Series GSE132758. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Early Pathogenesis of Cystic Fibrosis Gallbladder Disease in a Porcine Model
GEO Series GSE152145. Sus scrofa. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.