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1,356 results for “Human Activities”
Transcription profiling of activated human T cells induced by microgravity to identify apoptotic genes and other immune response genes
The purpose of this study was to search for microgravity-sensitive genes specifically for apoptotic genes influenced by the microgravity environment and other genes related to immune response. Experiment Overall Design: Two-group design with paired samples i.e. one 1G and one MMG culture came from the same donor. Therefore 6 samples came from 3 different donors. Experiment Overall Design: Donor 1 :GSM96146,GSM96147 Experiment Overall Design: Donor 2: GSM96148 GSM96149 Experiment Overall Design: Donor 3: GSM96150,GSM96151 Experiment Overall Design: Total RNA was submitted to and then labeled hybridized and data generated by the Baylor College Medicine Microarray Core Facility (333E One Baylor Plaza Houston TX 77030).
Global N Cycle: Fluxes and N2O Mixing Ratios Originating from Human Activity
Nitrogen is a major nutrient in terrestrial ecosystems and an important catalyst in tropospheric photochemistry. Over the last century human activities have dramatically increased inputs of reactive nitrogen (Nr, the combination of oxidized, reduced and organically bound nitrogen) to the Earth system. Nitrogen cycle perturbations have compromised air quality and human health, acidified ecosystems, and degraded and eutrophied lakes and coastal estuaries [Vitousek et al., 1997a, 1997b; Rabalais, 2002; Howarth et al., 2003; Townsend et al., 2003; Galloway et al., 2004]. To begin to quantify the changes to the global N cycle, we have assembled key flux data and N2O mixing ratios from various sources. The data assembled from different sources includes fertilizer production from 1920-2004; manure production from 1860-2004; crop N fixation estimated for three time points, 1860, 1900, 1995; tropospheric N2O mixing ratios from ice core and firn measurements, and tropospheric concentrations to cover the time period from 1756-2004. The changing N2O concentrations provide an independent index of changes to the global N cycle, in much the same way that changing carbon dioxide concentrations provide an important constraint on the global carbon cycle. The changes to the global N cycle are driven by industrialization, as indicated by fossil fuel NOx emission, and by the intensification of agriculture, as indicted by fertilizer and manure production and crop N2 fixation. The data set and the science it reflects are by nature interdisciplinary. Making the data set available through the ORNL DAAC is an attempt to make the data set available to the considerable interdisciplinary community studying the N cycle.
Diabetic Kidney Disease Induces Transcriptome Alterations Associated with Angiogenesis Activity in Human Mesenchymal Stromal Cells [mRNA]
GEO Series GSE217709. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing.
DAZL regulates proliferation of human primordial germ cell by direct binding to precursor miRNAs and enhances DICER processing activity
GEO Series GSE206466. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in human fibrosarcoma cells.
GEO Series GSE32441. Homo sapiens. 13 samples. Type: Expression profiling by array.
Human CCR6+ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity [Spsingh-10x-TCR-plus-transcriptome-kit]
GEO Series GSE227656. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
Bexmarilimab activates human tumor-associated macrophages to support adaptive immune responses in interferon-poor immune microenvironments
GEO Series GSE222649. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Human stem cell-derived pancreatic acini-like and duct-like organoids demonstrate lineage-specific differences to oncogene activation
GEO Series GSE169008. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Blood Transcriptional Profiles in Human Active and Latent Tuberculosis
GEO Series GSE19491. Homo sapiens. 498 samples. Type: Expression profiling by array.
scRNA sequencing time series of human iPSC-derived hematopoietic progenitors (with or without Notch activation from day 0-2) developing into T cells from day 12 to day 42 compared with freshly isolate
GEO Series GSE156111. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Mutation of a schizophrenia risk gene SETD1A alters neuronal network activity in human neurons through cAMP/PKA pathway
GEO Series GSE180648. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Activation of adult human pancreatic ductal and ductal progenitor-like cells requires extracellular matrix protein signaling [scRNA-seq]
GEO Series GSE233785. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity
GEO Series GSE77128. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Human Embryonic Stem Cell Spheroids exosomal miR-6766-3p alleviate activation of hepatic stellate cells and liver fibrosis by targeting TGFβRII in CCl4-induced liver fibrosis
GEO Series GSE164617. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by array.
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk]
GEO Series GSE110968. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq)
GEO Series GSE125167. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
The activation of the NF-κB-JNK pathway is independent of the PI3K-Rac1-JNK pathway involved in the bFGF-regulated human fibroblast cell migration
GEO Series GSE65193. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Systematic comparison of experimental and human obstructive cholestasis reveals conservation of canonical pathway activation and biomarkers relevant for cholestatic liver disease [mouse data set]
GEO Series GSE183882. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells
GEO Series GSE66796. Homo sapiens. 10 samples. Type: Methylation profiling by genome tiling array.
Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells [RNA_in_vitro_DC10_iDC_DC10CH]
GEO Series GSE180761. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.