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1,274 results for “Disease Model”

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geo24/100

Dysregulated synaptic gene expression and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease

GEO Series GSE84684. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2017View details →
geo24/100

Transcriptional profiling of a mouse model of Uromodulin Associated Kidney Disease (UAKD)

GEO Series GSE102566. Mus musculus. 107 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2017View details →
geo24/100

An integrative multiomic network model links the canonical lipid metabolism pathway to glucose regulation in coronary artery disease

GEO Series GSE157223. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2020View details →
geo24/100

Intravenous immunoglobulin (IVIg) ameliorates disease in a murine model of anti-laminin 332 mucous membrane pemphigoid

GEO Series GSE263026. Mus musculus. 46 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease

GEO Series GSE176160. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2022View details →
geo24/100

Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways

GEO Series GSE250567. Homo sapiens. 84 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo24/100

A Murine Model of Lyme Disease Demonstrates That Borrelia Species Colonize the Dura Mater and Induce Inflammation in the Central Nervous System.

GEO Series GSE149287. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

Transcriptome profiling in knock-in mouse models of Huntington's disease [Cortex_miRNA]

GEO Series GSE65769. Mus musculus. 168 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenFeb 2016View details →
geo24/100

Human branching cholangiocyte organoids recapitulate embryogenic bile duct development and provide an unique model to study biliary diseases. RNA-Seq

GEO Series GSE179599. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2022View details →
geo24/100

Establishment and disease modeling of non-small cell lung cancer organoids

GEO Series GSE119004. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2019View details →
geo24/100

Transcriptomic study identifies quercetin and rutin as repurposed drugs for Parkinson’s Disease in in vitro 6-OHDA model

GEO Series GSE198009. Homo sapiens. 16 samples. Type: Expression profiling by array.

openGEO-OpenJan 2023View details →
geo24/100

A Mouse Model for Metabolic Dysfunction-associated Steatotic Liver Disease and Hepatocellular Carcinoma

GEO Series GSE246223. Mus musculus; Homo sapiens. 160 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo24/100

Arteriovenous Fistulae in Chronic Kidney Disease and the Heart: Physiological, Histological, and Transcriptomic Characterization of a Novel Rat Model

GEO Series GSE211019. Rattus norvegicus. 23 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models

GEO Series GSE199320. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

Transcriptional profiling of striatum and cortex from a mouse model of Huntington's disease (Q140) crossed with Rgs9 heterozygous mice and Msh2 knockout mice [Msh2_6mon]

GEO Series GSE229817. Mus musculus. 64 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Transcriptional profiling of cerebral cortex from a mouse model of Huntington's disease (Q140) crossed with Msh3 heterozygous and homozygous mice [Msh3_cortex]

GEO Series GSE229826. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Identification and drug-induced reversion of molecular signatures of Alzheimer´s disease onset and progression in AppNL-G-F, AppNL-F and 3xTg-AD mouse models (RNA-seq: WT/3xTg)

GEO Series GSE168428. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →
geo24/100

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease II

GEO Series GSE195457. Mus musculus; Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
geo24/100

Expression Of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling In An Induced Pluripotent Stem Cell Model Of Systemic Amyloid Disease

GEO Series GSE153541. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2020View details →
geo24/100

Mechanistic Modelling of Recessive Disease through Allelic Integration of Variant Effects

GEO Series GSE313314. Saccharomyces cerevisiae; synthetic construct. 44 samples. Type: Other.

openGEO-OpenFeb 2026View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record