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978 results for “Instability”
Data from: Smooth enlargement of human standing sway by instability due to weak reaction floor and noise
Human quiet standing is accompanied by body sway. The amplitude of this body sway is known to be larger than would be predicted from simple noise effects, and sway characteristics are changed by neurological disorders. This large sway is thought to arise from nonlinear control with prolonged periods of no control (intermittent control), and a nonlinear control system of this kind has been predicted to exhibit bifurcation. The presence of stability-dependent transition enables dynamic reaction that depends on the stability of the environment, and can explain the change in sway characteristics that accompanies some neurological disorders. This research analyses the characteristics of a system model that induces transition, and discusses whether human standing reflects such a mechanism. In mathematical analysis of system models, (intermittent control-like) nonlinear control with integral control is shown to exhibit Hopf bifurcation. Moreover, from the analytical solution of the system model with noise, noise is shown to work to smooth the enlargement of sway around the bifurcation point. This solution is compared with measured human standing sway on floors with different stabilities. By quantitatively comparing the control parameters between human observation and model prediction, enlargement of sway is shown to appear as predicted by the model analysis.
Data from: Testing hypotheses of element loss and instability in the apparatus composition of complex conodonts: articulated skeletons of Hindeodus
Knowledge of the conodont skeleton, in terms of the morphology of the elements and the positions they occupy, provides the foundation for understanding of homology, taxonomy and evolutionary relationships in conodonts. This knowledge also underpins analyses of conodont functional morphology and feeding. Direct evidence of skeletal anatomy and apparatus architecture comes from natural assemblages: fossils that preserve together the articulated remains of the conodont apparatus, either collapsed onto a bedding plane or as clusters of elements in which juxtaposed and overlapping elements have been fused together by diagenetic minerals. Here we describe six clusters of the biostratigraphically important conodont Hindeodus parvus from the Lower Triassic Shangsi section, Sichuan Province, South China. Five of these clusters represent the partial remains of articulated skeletons, providing direct evidence of the number and arrangement of elements in the apparatus. Combined with data from previously published natural assemblages this provides a test of the hypothesis that Triassic conodonts had a reduced dentition. Hindeodus parvus possessed a complete raptorial array of two M and nine S elements (unpaired S0; symmetrically paired S1, S2, S3, S4); the paired P1 locations were occupied by carminiscaphate elements, but the apparatus lacked P2 elements. This is consistent with broader evidence for a particularly high degree of integration and constraint operating on the S–M array of morphologically complex conodonts, leading to conserved architecture of the array over a period of more than 250 million years. The loss of elements from the P domain implies a change in food processing ability and, given the predominance of data from P elements in conodont taxonomy and biostratigraphy, the hypothesis of element loss from the P domain has significant implications for the broader understanding of conodont diversity and evolutionary patterns.
Three-dimensional simulation results of Perkins instability in the midlatitude F-region ionosphere
<p>The simulated results for Perkins instability</p>
The data set to paper: Hydrolytic instability of laser-ablatively deposited CaSi2 coatings in air and neutral water affects the behavior of bone healing-related cell types
<p>Main message of this study is focused on calcium silicide (CaSi<sub>2</sub>) instability in humid air or pH-neutral water remains unknown, although the topochemical formation of silicene from CaSi<sub>2</sub> in various aqueous phases is a well-known process. The reseach reports on laser ablation of CaSi<sub>2</sub> in the vacuum and ethanol and examine the instability of the deposited coatings in humid air and neutral water. We further investigate the behavior of human mesenchymal stromal cells (hMSCs), vascular cells (HUVECS, human umbilical vein endothelial cells), and macrophages (derived from THP-1 cell line) in contact with the deposited coatings submerged in cell culture medium. </p>
Molecular basis for the evolved instability of a human G-protein coupled receptor
<p>Membrane proteins are prone to misfolding and degradation. This is particularly true for mammalian forms of the gonadotropin-releasing hormone receptor (GnRHR). Although they function at the plasma membrane, mammalian GnRHRs accumulate within the secretory pathway. Their apparent instability is believed to have evolved through selection for attenuated GnRHR activity. Nevertheless, the molecular basis of this adaptation remains unclear. We show that adaptation coincides with a C-terminal truncation that compromises the translocon-mediated membrane integration of its seventh transmembrane domain (TM7). We also identify a series of polar residues in mammalian GnRHRs that compromise the membrane integration of TM2 and TM6. Reverting a lipid-exposed polar residue in TM6 to an ancestral hydrophobic residue restores expression with no impact on function. Evolutionary trends suggest variations in the polarity of this residue track with reproductive phenotypes. Our findings suggest that the marginal energetics of cotranslational folding can be exploited to tune membrane protein fitness.</p>
Data associated with "Survival outcomes are associated with genomic instability in luminal breast cancers".
<p>Data utilised in <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0245042">Survival outcomes are associated with genomic instability in luminal breast cancers</a>.</p>
Competing controls of fluid overpressurization and chloritization on strength and instability of faults in granite: Implications for seismicity triggered by fluid-injection
<p>Fluids injection for hydraulic stimulation and fracturing, typical in the development of enhanced geothermal systems (EGS) in granites, can reactivate deep faults and induce seismicity. Such faults typically contain chlorite coatings as an alteration product that may impact styles of deformation – aseismic through seismic. We performed shear experiments on simulated granite fault gouges under conditions typifying a geothermal reservoir at ~4 km depth with a confining pressure of 110 MPa, a temperature of 150℃, fluid pressures of 21-80 MPa, and chlorite contents of 0-100%, to investigate the influence of effective stress and mineral composition on fault strength and stability. Our results show a transition from velocity-strengthening to velocity-weakening behavior in simulated granite gouge when the fluid pressure was elevated from 21 to 80 MPa, characterized by a transition from fault compaction to dilation – as revealed by microstructural observations – with implications in enabling unstable failure. Conversely, increasing chlorite content stabilizes slip but reduces frictional strength. The microstructures of these mixed gouges exhibit shear localized on chlorite-enriched planes and promoting fault sliding. These results suggest that earthquake ruptures occurring during fluid injection can be facilitated by fluid overpressures. And that controlling fluid overpressures and being aware of the presence of alteration minerals are both important controls in mitigating such injection-induced seismic risks.</p>
Generalized Rayleigh-Taylor Instability: Ion Inertia, Acceleration Forces, and E Region Drivers
<p>electron density and growth rate data files</p>
Data and scripts for Mellado et al. 2024 Developmental instability, body mass, and reproduction predict immunological response in short-tailed bats. Current Zoology (In Press). DOI:10.1093/cz/zoae034
<p>Data and Scripts used in Mellado et al. 2024 Developmental instability, body mass, and reproduction predict immunological response in short-tailed bats.</p> <p>Breno Mellado, Lucas de O. Carneiro, Marcelo R. Nogueira, L. Gerardo Herrera M., Ariovaldo P. Cruz-Neto, Leandro R. Monteiro</p> <p>File ReadmeFirst.txt = this desctription</p> <p>File Melladoetal2024-CurrZool_Supplementary_Materials.pdf = Supplementary figures and tables for Mellado et al. 2024.</p> <p>File Carollia_PHA.txt = data set with 139 observations. Variables are: Sex = factor with sex (M/F), BMass = Body mass in g, ForA = unsigned forearm asymmetry (absolute scale, mm), ForL = right forearm length in mm, IPHA = PHA index, BSeason = factor with period of breeding season (early/late)</p> <p>File Carollia_phaTL.txt = data set with 50 observations. Variables are: BMass = Body mass in g, ForL = right forearm length in mm, IPHA = PHA index, ForA = forearm asymmetry (absolute scale, mm), TL = testicle length in mm, BSeason = factor with period of breeding season (early/late)</p> <p>File pha36hours.txt = data set with 144 observations (24 individuals measured at 0,3,6,10,24,36 hours after injection). Variables are: Ind = Individual identifier, Hour = Hours since injection of PHA solution, IPHA: PHA index</p> <p>script_Carollia_PHA.R = R script for analyses and figures</p>
Figure 1 from: Entiauspe-Neto OM, de Sena A, Tiutenko A, Loebmann D (2019) Taxonomic status of Apostolepis barrioi Lema, 1978, with comments on the taxonomic instability of Apostolepis Cope, 1862 (Serpentes, Dipsadidae). ZooKeys 841: 71-78. https://doi.org/10.3897/zookeys.841.33404
Figure 1 Dorsal, lateral and ventral illustrations of previously recognized taxa, Apostolepisdimidiata (A) and A.barrioi (B), according to the diagnoses of Cabral et al. (2017). However, these represent merely phenotypic variations of A.dimidiata and, according to the descriptions of Jan (1862) and Lema (1978), both holotypes of A.barrioi and A.dimidiata present the bottom coloration.
Figure 2 from: Entiauspe-Neto OM, de Sena A, Tiutenko A, Loebmann D (2019) Taxonomic status of Apostolepis barrioi Lema, 1978, with comments on the taxonomic instability of Apostolepis Cope, 1862 (Serpentes, Dipsadidae). ZooKeys 841: 71-78. https://doi.org/10.3897/zookeys.841.33404
Figure 2 The impact of the taxonomic history of Apostolepis Cope, 1862 species. The line refers to the cumulative number of species considered as valid during the time span, suffering either reductions from synonymies or additions from descriptions and revalidations. Inset picture: Apostolepis sp. from Serra do Cachimbo, Pará, Brazil.
Data of "Saturation properties of whistler wave instability in a plasma with two electron components"
<p>Data of 1D particle simulation results, containing energy and temperature data.</p>
ClariPhy: Physics-Informed Image Deblurring with Transformers for Hydrodynamic Instability Analysis
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Dataset for: Magnetic Mineralogy and Paleomagnetic Record of the Nama Group: Implications for Large-Scale Remagnetization of West Gondwanaland and Ediacaran Geomagnetic Instability
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Ring-beam instability data files
<p>The data for each figure in the paper is provided in a separate file.</p>
Radiative properties of pair-instability supernova explosions
<p>Model spectra from <a href="https://ui.adsabs.harvard.edu/abs/2013MNRAS.428.3227D">Dessart et al. 2013, MNRAS, 428, 3227</a></p>
Hemodynamic Instability Index: The Impact to Care With a New Predictive Indicator
ClinicalTrials.gov study NCT02185521. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Knee Arthroplasty Instability Study
ClinicalTrials.gov study NCT05676437. IPD Sharing: NO. Countries: 0. Publications: 3.
Prediction of Hemodynamic Instability in Patients Undergoing Surgery
ClinicalTrials.gov study NCT03533205. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Phamacological Reversal of Airway Instability During Sedation
ClinicalTrials.gov study NCT01171118. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.