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11,837 results for “Stress;”
GWAS analysis for tolerance to heat stress and milk production, in subtropical Egyptian goats
<p>The conservation of local Egyptian goat genotypes has been a national program since 2009. Our study investigated different subtropical Egyptian goat populations (367 does) from different harsh ecological zones(hot Upper Egypt, Coastal Zone of Western Desert, and Wahati Desert Oasis) to identify genes associated with heat stress. We examined the physiological response of animals that were exposed to simulated summer grazing conditions, and physiological parameters including respiration rate, gas volume, rectal temperature, and skin temperature. Temperature Humidity Index ranged from 98.6 to 109.3, indicating that the animals were under severe heat stress. Results showed significant differences between the populations in their tolerance to heat stress, with Saidi goats being the most adapted to hot-dry conditions. Respiration rate was found to be the most reliable physiological trait for differentiating between animals in their tolerance to heat stress. The GWAS analysis involved 157 genotypes and 54,032 marker-SNPs, revealing 90 SNPs associated with heat stress and 70 SNPs associated with milk production. Chromosome 1 had the highest number of SNPs associated with heat-stress traits, while chromosome 4 exhibited the largest number of significant SNPs associated with milk production. Several genes were associated with heat stress response and tolerance in goats. These genes were categorized into three main groups: heat stress response, stress response, and reproduction, and feed intake. The first group includes USP54, KDM6A, and ETNPPL, which have multiple functions, such as steroid biosynthesis, metabolism, and stress response, and are also involved in key biological processes such as reproduction, immune response, and metabolism. The second group, which is mostly associated with immune response, includes GLTSCR2 and NAALADL2. Finally, a group of genes that may control animal feed intakes, including TRPM3 and ZBTB8A. Additionally, several genes, such as FHIT, GALNT18, RAPGEF5, and RBFOX1, linked to milk production, are known to be linked fertility, and fatty acid composition. These findings provide insights into the potential roles of these genes in heat stress response and tolerance in goats, and the genetic basis for improved milk production and animal welfare and can be used as selection markers in the ongoing breeding programs.</p>
Dataset in support of "Laboratory wave and stress measurements quantify the aerodynamic sheltering in extreme winds" by Tan et al. (2023, JGR: Oceans)
<p><strong>Data introduction:</strong></p> <p> There are three datasets used in this research: dataset 1 from Wind-Only (WO) experiment, dataset 2 from JONSWAP experiment with 10-cm significant wave height (J10), and dataset 3 from monochromatic wave experiment with 7.5-cm amplitude (M7.5).</p> <p> Each dataset contains quality-controlled data of the respective experiment mentioned above. The data files are in the mat (MATLAB) format. There are 9 mat files in each dataset, and each file represents data collected under a specific wind forcing condition, with the fan frequency in the 10-50 Hz range with 5 Hz interval.</p> <p> Each file contains four variables: <em>seg</em> (water elevation time series collected by the wave-wire with the units of <em>m</em>, demeaned and detrended), <em>U</em> (along-tank, downwind component of wind sampled by the IRGASON anemometer with the units of <em>m/s</em>), <em>V</em> (cross-tank component of wind sampled by the IRGASON anemometer with the units of <em>m/s</em>), and <em>W</em> (vertical component of wind collected by the IRGASON anemometer with the units of m/s). All four variables were collected at a sampling frequency of 20 Hz.</p>
Recorded plant sounds from: Sounds emitted by plants under stress are airborne and informative
<p>Stressed plants show altered phenotypes, including changes in color, smell, and shape. Yet, airborne sounds emitted by stressed plants have not been investigated before. Here we show that stressed plants emit airborne sounds that can be recorded from a distance and classified. We recorded ultrasonic sounds emitted by tomato and tobacco plants inside an acoustic chamber, and in a greenhouse, while monitoring the plant's physiological parameters. We developed machine learning models that succeeded in identifying the condition of the plants, including dehydration level and injury, based solely on the emitted sounds. These informative sounds may also be detectable by other organisms. This work opens new avenues for understanding plants and their interactions with the environment and may have a significant impact on agriculture.</p>
Supplementary data to publication "Abomasal infusion of essential fatty acids and conjugated linoleic acid during late pregnancy and early lactation affects immunohematological and oxidative stress markers in dairy cows"
<p>Supplementary data to publication "Abomasal infusion of essential fatty acids and conjugated linoleic acid during late pregnancy and early lactation affects immunohematological and oxidative stress markers in dairy cows" in Journal of Dairy Science; DOI: <a href="https://doi.org/10.3168/jds.2022-22514">https://doi.org/10.3168/jds.2022-22514</a></p>
The impact of pharmaceutical form and simulated side effects in an open-label-placebo RCT for improving psychological distress in highly stressed students (Open Data and Open Materials)
<p> Open-label placebo (OLP) may be utilized to reduce psychological distress. Yet, potential contextual effects have not been explored. We investigated the impact of pharmaceutical form and the simulation of side effects in a parallel group RCT (DRKS00030987). A sample of 177 highly stressed university students at risk of depression were randomly assigned by computer generated tables to a one-week intervention with active or passive OLP nasal spray or passive OLP capsule or a no-treatment control group. After the intervention, groups differed significantly in depressive symptoms but not regarding other outcomes of psychological distress (stress, anxiety, sleep quality, somatization), well-being or treatment expectation. OLP groups benefitted significantly more compared to the no-treatment control group (<em>d</em>=.40), OLP nasal spray groups significantly more than the OLP capsule group (<em>d</em>=.40) and the active OLP group significantly more than the passive OLP groups (<em>d</em>=.42). Interestingly, before intervention, most participants, regardless of group assignment, believed that the OLP capsule would be most beneficial. The effectiveness of OLP treatments seems to be highly influenced by the symptom focus conveyed by the OLP rationale. Moreover, pharmaceutical form and simulation of side effects may modulate efficacy, while explicit treatment expectation seems to play a minor role.</p>
Data from: Developmental stress does not induce genome-wide DNA methylation changes in wild great tit (Parus major) nestlings
<p class="MsoNormal"><span>The environment experienced during early life is a crucial factor in the life of many organisms. This early life environment has been shown to have profound effects on morphology, physiology and fitness. However, the molecular mechanisms that mediate these effects are largely unknown, even though this is essential for our understanding of the processes that induce phenotypic variation in natural populations. DNA methylation is an epigenetic mechanism that has been suggested to explain such environmentally induced phenotypic changes early in life. To investigate whether DNA methylation changes are associated with experimentally induced early developmental effects, we cross-fostered great tit (<em>Parus major</em>) nestlings and manipulated their brood sizes in a natural study population. We assessed experimental brood size effects on pre-fledging biometry and behaviour. We linked this to genome-wide DNA methylation levels of CpG sites in erythrocyte DNA, using 122 individuals and an improved epiGBS2 laboratory protocol. Brood enlargement caused developmental stress and negatively affected nestling condition, predominantly during the second half of the breeding season, when conditions are harsher. Brood enlargement, however, affected nestling DNA methylation in only one CpG site and only if hatch date was taken into account. In conclusion, this study shows that nutritional stress in enlarged broods does not associate with direct effects on genome-wide DNA methylation. Future studies should assess whether genome-wide DNA methylation variation may arise later in life as a consequence of phenotypic changes during early development.</span></p>
Data set used in "Effect of turbulence and viscosity models on wall shear stress derived biomarkers for aorta simulations"
<p>Data set used in "Effect of turbulence and viscosity models on wall shear stress derived biomarkers for aorta simulations"</p> <p>Includes the data for 20 heartbeats. Divided into external and internal walls regions. </p>
Data from: Dietary restriction fails to extend life in stressful environments
<ol> <li>Moderate dietary restriction often prolongs life in laboratory animals, and this response has been interpreted as an adaptive strategy that promotes survival during famine. However, dietary restriction can also increase frailty, and it therefore remains unclear whether restricted diets prolong life under stressful conditions like those experienced by wild animals. </li> <li>We manipulated adult dietary protein of <em>Drosophila</em> <em>melanogaster</em> across a gradient of ambient temperature and examined effects on survival. To test for trade-offs, we also quantified the reproduction, and performance of F1, F2 and F3 descendants.</li> <li>We found that protein restriction increased longevity of one or both sexes at benign ambient temperatures (25°C, 27°C) but failed to extend longevity of flies maintained in cold (21°C, 23°C) or hot (29°C) conditions. Instead, in females, protein restriction resulted in strongly elevated mortality at cold temperatures. Protein restriction also generally reduced reproductive performance and did not consistently enhance performance of F1, F2 or F3 descendants. </li> <li>Taken together, our results challenge the long-held idea that extended longevity of diet-restricted laboratory animals represents an adaptive survival strategy in natural populations. Our findings suggest instead that this response is an artefact of benign laboratory conditions, and that DR-induced life extension might not be achieved in the more stressful conditions experienced in the wild. </li> </ol>
Wrist-worn sensor validation for heart rate variability and electrodermal activity detection in a stressful driving environment
<p>The current dataset contributes to assess the accuracy of the Empatica 4 (E4) wristband for the detection of heart rate variability (HRV) and electrodermal activity (EDA) metrics in stress-inducing conditions and growing-risk driving scenarios. Heart Rate Variability (HRV) and ElectroDermal Activity (EDA) signals were recorded over six experimental conditions (i.e., Baseline, Video Clip, Scream, No Risk Driving, Low-Risk Driving, and High-Risk Driving) and by means of two measurement systems: the E4 device and a gold standard system. The raw quality of the physiological signals was enhanced by means of robust semi-automatic reconstruction algorithms. Heart Rate Variability time-domain parameters showed high accuracy in motion-free experimental conditions, while Heart Rate Variability frequency-domain parameters reported sufficient accuracy in almost every experimental condition.</p>
Endingless Locatives in Vedic Sanskrit by Stress Type
<p>Data for the forthcoming paper "The Unexceptional Stress of the 'Endingless Locative' in Indo-European" (to appear in the <em>Proceedings of the 33rd Annual UCLA Indo-European Conference</em>). Collection of attested "endingless locatives" in Vedic Sanskrit, organized by paradigmatic stress type and whether their stress pattern is consistent with the principles hypothesized in the paper.</p>
High-temperature stress induces bacteria-specific adverse and reversible effects on Ulva (Chlorophyta) growth and its chemosphere in a reductionist model system
<p>This dataset contains raw files from a mass spectrometric analysis of the exo-metabolome of the green macroalga <em>Ulva mutabilis</em> (Chlorophyta).</p>
Interactive effects of immediate and ancestral salt stress on fitness in duckweed
<p><em>Premise of Research</em></p> <p>Organisms that reproduce asexually must respond to abiotic stresses in their environment while contending with the potential disadvantage of the reduced ability for genetic variation through recombination. Common duckweed (<em>Lemna minor</em>) is an aquatic plant that reproduces predominantly asexually through the budding of ramets. As a freshwater plant, duckweed experiences stress from salt (e.g., NaCl), which detrimentally affects growth, photosynthesis, and cellular processes. We took a demographic approach to examine whether ancestral exposure to salt stress affects the ability of duckweed offspring to tolerate immediate exposure to the same stress.</p> <p><em>Methodology</em></p> <p>We placed three consecutive clonal generations of duckweed in an environment with 2 g L<sup>-1</sup> NaCl (non-lethal salt stress) or 0 g L<sup>-1</sup> NaCl (control), followed by an additional 0-3 generations in the control environment to vary the presence and schedule of ancestral stress. After these treatments, we used the offspring produced as focal plants for the experiment. Half were placed into the salt-stress environment, and half were placed in control conditions, and focal plants were tracked longitudinally.</p> <p><em>Pivotal Results</em></p> <p>Immediate stress decreased fitness, due to a slowing of reproduction, suggesting a cost of stress tolerance. The effects of ancestral stress, and the interaction of immediate and ancestral stress, were more complex. Specifically, recent ancestral stress induced plants to produce offspring more quickly, but with the potential cost of lowered offspring quality.</p> <p><em>Conclusions</em></p> <p>Our results amplify findings that responses to, and fitness consequences of, current stressors can be contingent on past exposure.</p>
Constraining an eddy energy dissipation rate due to relative wind stress for use in energy budget-based eddy parameterisations
<p>Code and data to reproduce results in the EGU Ocean Science journal paper, entitled 'Constraining an eddy energy dissipation rate due to relative wind stress for use in energy budget-based eddy parameterisations'.</p> <p>The data and corresponding scripts in this repository are:</p> <ul> <li>MITgcm simulation data for an anticyclone and cyclone under absolute and relative wind stress. <ul> <li>ACE_eta_{absolute or relative}_10km_A25_v2_ext.nc</li> <li>ACE_tau_{absolute or relative}_10km_A25_v2_ext.nc</li> <li>ACE_temp_{absolute or relative}_10km_A25_v2_ext.nc</li> <li>CE_eta_{absolute or relative}_10km_A25_v2.nc</li> <li>CE_tau_{absolute or relative}_10km_A25_v2.nc</li> <li>CE_temp_{absolute or relative}_10km_A25_v2.nc</li> </ul> </li> <li>Mean energetics computed using eddy_energy_mean.m. User may need to comment out lines of code relating to wvel. This also requires geostrophic_uv.m, rho_ref.mat, and ocean_vertical_grid.nc. <ul> <li>{ACE or CE}_energy_{absolute or relative}_total_10km_A25_mean.nc</li> </ul> </li> <li>Predicted eddy energy computed using predict_*.m scripts. n.b. viscous term left in absolute scripts, though we only need the first index of total eddy energy in abs cases. The abs cases are really just making the abs.mat files, see time_series_plots.py.</li> <li>Time-series figures (3 and 5) produced using time_series_plots.py.</li> <li>Initial figures (1 and 2) produced using initial_plots.py.</li> <li>Relative vorticity in Fig. 4 computed and plotted using eddy_evolution_plot.py.</li> <li>Dissipation rates computed in calc_dissipation_rate.m. Requires dynmodes.m and GSW toolbox to run. Also needs data Chelton2011_Le.csv and Chelton2011_Rd.csv. <ul> <li>diss_rate*.nc</li> </ul> </li> <li>Dissipation rate and climatology figures (6, 7, 8, and 9) made in diss_rate_plot.py</li> </ul> <p>Information and data needed to run the MITgcm can be found <a href="https://github.com/thomaswilder/jpo_eddy-scripts">here</a>.</p>
Raw data of Decoding the state of stress and fluid pathways along the Andean Southern Volcanic Zone
<p>Raw data of the manuscript. </p> <p>Focal mechanisms and fault slip data of each volcano are attached to this supplementary material, in text files ending with “.fdt”, which can be found in the “Raw Data” folder. The fault slip data, on these text files, are write as strike/dip of the fault plane; trend/plunge of the rake, and the sense of displacement (N=normal R=Reverse), following the MIM-software input format. Note that by defining the displacement as normal o reverse, we are defining that the hanging wall block is going up or down, but it does not mean that the fault kinematics is restricted to normal or reverse. The fault kinematics can be dextral or sinistral strike-slip kinematics depending on the angle between the horizon and the rake projected in the fault plane. In the case of focal mechanisms, one focal mechanism is characterized by two rows of data that represent both focal plane solutions, following the MIM-software format. These “.fdt” files are ready to be analyzed in the MIM software that is freely available on the internet (at <a href="http://bs.kueps.kyoto-u.ac.jp/tsg/software/mim/">http://bs.kueps.kyoto-u.ac.jp/tsg/software/mim/</a>,visited august 2022).</p> <p>Complementarily, an explanation of data, its reference, spatial correlation with the volcano, and methodological details are explained in the excel table “Details_of_Database.xlsx”. Moreover, locations of the fault slip data and epicenter of focal mechanisms can be found in the attached folder “location of data” as Google Earth files (.kmz).</p>
Standard heat stress indices may not be appropriate for assessing marathons
<p>Code and data supporting the manuscript "Standard heat stress indices may not be appropriate for assessing marathons".</p> <p>These scripts rely on some of the data being present in a certain location. But to reproduce this based on the included data, you need only run pet_calculations.py as all the data area in comrades.nc</p> <p>The order in which the scripts were run was:</p> <p>1. get_utci.py - downloads ERA5-HEAT data<br> 2. unzip_era5_heat.sh - unzips that data<br> 3. query.py - subsets ERA5-HEAT data, and ERA5 data from CEDA<br> 4. pet_calculations.py - calculations and analysis</p> <p>pet_calculations.ipynb shows the results of pet_calculations.py in notebook form.</p>
Host-pathogen interactions under pressure: a review and meta-analysis of stress-mediated effects on disease dynamics
<p>Human activities have increased the intensity and frequency of natural stressors and created novel stressors, altering host-pathogen interactions, and changing the risk of emerging infectious diseases. Despite the ubiquity of such anthropogenic impacts, predicting the directionality of outcomes has proven challenging. Here, we conduct a review and meta-analysis to determine the primary mechanisms through which stressors affect host-pathogen interactions and to evaluate the impacts stress has on host fitness (survival and fecundity) and pathogen infectivity (prevalence and intensity). We assessed 891 effect sizes from 71 host species (representing seven taxonomic groups) and 78 parasite taxa from 98 studies. We found that infected and uninfected hosts had similar sensitivity to stressors and that responses varied according to stressor type. Specifically, limited resources compromised host fecundity and decreased pathogen intensity, while abiotic environmental stressors (e.g., temperature and salinity) decreased host survivorship and increased pathogen intensity, and pollution increased mortality but decreased pathogen prevalence. We then used our meta-analysis results to develop Susceptible-Infected theoretical models to illustrate scenarios where infection rates are expected to increase or decrease in response to resource limitation or environmental stress gradients. Our results carry implications for conservation and disease emergence and reveal areas for future work. </p>
The raw microarray data and the differential expression analysis results from "Manipulating the growth environment through co-culture to enhance stress tolerance and viability of probiotic strains in the gastrointestinal tract".
<p>The signal data for each spot were subsequently quantified by using Feature Extraction software (Agilent Technologies).M1.txt to M5.txt: monoculture; C1.txt to C5.txt: co-culture; P1.txt to P5.txt: pH-controlled monoculture. The differential expression analysis results were obtained by using limma.</p>
Cooling Vest May Reduce Heat Stress During Surgery
ClinicalTrials.gov study NCT04511208. IPD Sharing: YES. Countries: 1. Publications: 1.
Personalized Trials for Stress Management Against Standard of Care
ClinicalTrials.gov study NCT05408832. IPD Sharing: YES. Countries: 1. Publications: 1.
Mobile Self-Management Program for Stress Reduction in Young Adults
ClinicalTrials.gov study NCT07174544. IPD Sharing: NO. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.