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Dataset results
784 results for “Tregs”
Cut-and-run sequencing of adipose Treg cells with anti-HIF-1α and anti-PPAR-γ antibodies
GEO Series GSE164256. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TCR-seq to study features of the transcriptome and TCR repertoire of a stably persisting population of regulatory T cells generated in mice with autoimmune inflammation by conversion from Treg "wannab
GEO Series GSE179708. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells [RNA-Seq - induced Treg cells].
GEO Series GSE131589. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing.
Potent anti-tumor immunity and reversal of CD8 T cell exhaustion by spatially and functionally targeting Treg cells in the tumor microenvironment
<p>1×10<sup>6</sup> of splenic GFP<sup>+</sup> Tregs were purified from WT (n=4) and KO mice (n=4) via FACS isolation. RNA was extracted using RNeasy Micro Kit (Qiagen) following its standard protocol and RNA degradation and contamination was monitored on 1% agarose gels. For RNA sequencing, libraries were prepared using NEBNext® Ultra TM RNA Library Prep Kit for Illumina® (NEB, USA) following manufacturer’s recommendations and index codes were added to attribute sequences to each sample. The clustering of the index-coded samples was performed on a cBot Cluster Generation System using PE Cluster Kit cBot-HS (Illumina) according to the manufacturer’s instructions. After cluster generation, the library preparations were sequenced on an Illumina platform and paired-end reads were generated. All samples were prepared at the same time and sequenced on the same lane. Original image data file from high-throughput sequencing platforms (like Illumina) is transformed to sequenced reads (called Raw Data or Raw Reads) by CASAVA base recognition (Base Calling). Raw data in FASTQ format were processed through fastp. In this step, clean data (clean reads) were obtained by removing reads containing adapter and poly-N sequences and reads with low quality from raw data. All the downstream analyses were based on the clean data with high quality. Reference mouse genome and gene model annotation files were downloaded from genome website browser (NCBI/UCSC/Ensembl). Paired-end clean reads were mapped against the reference genome using the Spliced Transcripts Alignment to a Reference (STAR) software. FeatureCounts was used to count the read numbers mapped of each gene. And then RPKM (Reads Per Kilobase of exon model per Million mapped reads) of each gene was calculated based on the length of the gene and reads count mapped to this gene. The FPKM gene expression matrix, R code, DEG list, and targeted gene list are uploaded in this project.</p>
Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2)
ClinicalTrials.gov study NCT06052436. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Changes of Treg Cells Frequency and Function During Antiviral Therapy
ClinicalTrials.gov study NCT03210493. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Treatment of Refractory cGVHD by Donor-derived Treg Cell Injection Combined With Recombinant Human Interleukin-2
ClinicalTrials.gov study NCT06920199. IPD Sharing: NO. Countries: 1. Publications: 0.
UVB-induced Treg Cells Exert Antigen-specific Suppression Through LAG-3
ClinicalTrials.gov study NCT05636839. IPD Sharing: NO. Countries: 1. Publications: 0.
Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro
ClinicalTrials.gov study NCT04661254. IPD Sharing: Not stated. Countries: 1. Publications: 0.
T Regulatory Lymphocytes (Treg) Depletion for Cancer Treatment Efficacy and Safety Study
ClinicalTrials.gov study NCT00986518. IPD Sharing: Not stated. Countries: 1. Publications: 0.
DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab
ClinicalTrials.gov study NCT03688178. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Autologous Tregs for Aplastic Anaemia
ClinicalTrials.gov study NCT05386264. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells
ClinicalTrials.gov study NCT01064219. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Nivolumab in mRCC Patients: Treg Function, T-cell Access and NK Interactions to Predict and Improve Efficacy
ClinicalTrials.gov study NCT03891485. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic
ClinicalTrials.gov study NCT07123038. IPD Sharing: NO. Countries: 1. Publications: 0.
Regulatory T Cells (Tregs) in Polymorphic Light Eruption
ClinicalTrials.gov study NCT00555178. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Enumeration and Function Analysis of Treg Cells in Peripheral Blood of HCC Patients Before and After Ablation Therapy
ClinicalTrials.gov study NCT01668381. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Multiple Donor Treg DLI for Severe Refractory Chronic GVHD
ClinicalTrials.gov study NCT02749084. IPD Sharing: NO. Countries: 1. Publications: 0.
Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation
ClinicalTrials.gov study NCT05993611. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection
ClinicalTrials.gov study NCT05084768. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.