Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
715
datasets available to search
ShareScore release 0.9.0
Dataset results
715 results for “folding”
Fig. 4 in Suraqalatia Brasieri Görmuş, Lawa & Nuaimy, 2017 (Larger Benthic Foraminifera; Suraqalatiidae N. Fam.) From The Late Maastrichtian Of The Tarbur Formation (Zagros Fold-Thrust-Belt) And Remarks On Dicyclina Munier-Chalmas, 1887
Fig. 4 Suraqalatia brasieri Görmüş, Lawa & Al Nuaimy, upper Maastrichtian Tarbur Formation of Mandegan (a, e) and Naghan sections (b–d, f); oblique, partly tangential sections. Abbreviations: D = Dicyclina, L = Loftusia, N = Neobalkhania, O = Omphalocyclus. Scale bars = 1 mm. Thin-sections: Rt 63 (a), 2NG 183 (b), Rt 36 (c), 2NG 146 (d), 2NG 169 (f).
Fig. 2 in Suraqalatia Brasieri Görmuş, Lawa & Nuaimy, 2017 (Larger Benthic Foraminifera; Suraqalatiidae N. Fam.) From The Late Maastrichtian Of The Tarbur Formation (Zagros Fold-Thrust-Belt) And Remarks On Dicyclina Munier-Chalmas, 1887
Fig. 2 Distribution (total vertical range) of Suraqalatia brasieri Görmüş, Lawa & Al Nuaimy and some other larger benthic foraminifera in the Tarbur Formation of the Mandegan section.
Alphafold2_ab_initio iterative predictions for folding intermediate identification
<div>Iterative structure predictions for protein PDB ids starts from 4.</div>
Alphafold2_ab_initio iterative predictions for folding intermediate identification
<div>Iterative structure predictions for protein PDB ids starts from 3.</div> <div> <div> <p> </p> </div> </div>
Data from: Catalytic self-folding of 2D structures through cascading magnet reactions
While thousands of proteins involved in development of the human body are capable of self-assembling in a distributed manner from merely 20 types of amino acid, macroscopic products that can be assembled spontaneously from `alive' components remains an aspiration in engineering. To attain such a mechanism, a major challenge lies in understanding which attributes from the bio-molecular realm must be leveraged at the macro-scale. Inspired by protein folding, we present a centimetre-size 1D tile chain whose self-folding processes are directed by structure-embedded magnetic interactions, which can theoretically self-assemble into convex 2D structures of any size or shape without the aid of a global `controller'. Each tile holds two magnets contained in paths designed to control their interactions. Once initiated by a magnetic unit (termed Catalyst), the chain self-reconfigures by consuming magnetic potential energy stored between magnet pairs, until the final 2D structure is reached at an energetic minimum. Both simulation and experimental results are presented to illustrate the method's efficacy on chains of arbitrary length. Results demonstrate the promise of a physically implemented, bottom-up, and scalable self-assembly method for novel 2D structure manufacturing, bridging the bio-molecular and mechanical realms.
Data from: Sequence entropy of folding and the absolute rate of amino acid substitutions
Adequate representations of protein evolution should consider how the acceptance of mutations depends on the sequence context in which they arise. However, epistatic interactions among sites in a protein result in hererogeneities in the substitution rate, both temporal and spatial, that are beyond the capabilities of current models. Here we use parallels between amino acid substitutions and chemical reaction kinetics to develop an improved theory of protein evolution. We constructed a mechanistic framework for modelling amino acid substitution rates that uses the formalisms of statistical mechanics, with principles of population genetics underlying the analysis. Theoretical analyses and computer simulations of proteins under purifying selection for thermodynamic stability show that substitution rates and the stabilization of resident amino acids (the 'evolutionary Stokes shift') can be predicted from biophysics and the effect of sequence entropy alone. Furthermore, we demonstrate that substitutions predominantly occur when epistatic interactions result in near neutrality; substitution rates are determined by how often epistasis results in such nearly neutral conditions. This theory provides a general framework for modelling protein sequence change under purifying selection, potentially explains patterns of convergence and mutation rates in real proteins that are incompatible with previous models, and provides a better null model for the detection of adaptive changes.
Catalyst-Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides
<p>Data underlying the figures in the publication “Catalyst-Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides”, published in <em>Angew. Chem. Int. Ed.,</em> <strong>2020</strong>, 59, 18390–18394. <a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202005733">https://onlinelibrary.wiley.com/doi/10.1002/anie.202005733</a></p> <p>Table of contents:</p> <p><strong>1. Dataset</strong>; Word file containing: synthesis, experimental data, general procedures for the preparation of the catalyst, overview and methodology for nonreduced transannular polyketide cyclizations, selectivity, methodology and overview of transannular polyketide cyclization cascades (partially reduced), and NMR & X-ray data of the compounds in the publication.</p>
294-fold mini all-α protein library encoded by 7,350 amino-acid sequences (project "flood of fold" )
<p>This repository includes 3 compressed archive files for the “flood-of-fold” mini-protein library project. </p> <ol> <li>FloodOfFolds_294_backbone_models.tar.gz includes 294 mini all-α backbone models showing distinct topologies (folds). They are poly-VAL models. </li> <li>FloodOfFolds_7350_designs_MODEL.tar.gz includes 7,350 design protein models in the pdb format for the 294 mini-protein library. 25 amino-acid sequences were designed for each backbone model (25 x 294 = 7,350). </li> <li>FloodOfFolds_7350_designs_FASTA.tar.gz includes 7,350 fasta files derived from the pdb files in FloodOfFolds_7350_designs_MODEL.tar.gz.<br> </li> </ol> <p>See also here for results of folding simulations: https://zenodo.org/record/5526849#.YWRhFBBBw1I</p> <p>Acknowledgement: K.S. and S.M. would like to deeply thank Koga laboratory at Institute for Molecular Science providing computational resources. Most of the computations for model building and folding simulations were performed using the facilities at the Research Center for Computational Science, Okazaki, Japan.</p>
Figure 4 from: Juswara L, Schuiteman A, Droissart V (2016) Four new orchid species from the Lengguru fold belt, West Papua, Indonesia. PhytoKeys 61: 47-59. https://doi.org/10.3897/phytokeys.61.7590
Figure 4 - Photographs of living type specimens and habitats. Dendrobium taeniocaule: A habitat and habit B plant C flower and part of pseudobulb D flower, front view E flower, side view. Taeniophyllum pyriforme: F habitat and habit G plant and inflorescence H inflorescence and flowers close-up. Photos: Vincent Droissart.
Figure 2 from: Juswara L, Schuiteman A, Droissart V (2016) Four new orchid species from the Lengguru fold belt, West Papua, Indonesia. PhytoKeys 61: 47-59. https://doi.org/10.3897/phytokeys.61.7590
Figure 2 - A Bulbophyllum leucoglossum: 1 flower 2 dorsal sepal 3 lateral sepal 4 petal; 5, lip, adaxial view 6 lip, abaxial view 7 detail of crest on lip 8 column and base of lip; all after Droissart & Juswara 1789; B Dendrobium centrosepalum: 1 flower 2 flower, lateral view 3 floral bract 4 dorsal sepal 5 lateral sepal 6 petal 7 lip 8 flower, cut open 9 column 10 anther 11 pollinia; all after Droissart & Juswara 1736; C Dendrobium taeniocaule: 1 flower 2 dorsal sepal 3 lateral sepal 4 petal 5 lip 6 mentum 7 column, lateral view 8 column, ventral view; all after Droissart & Juswara 1739; D Taeniophyllum pyriforme: 1 flower 2 dorsal sepal 3 lateral sepal 4 petal 5 lip 6 column 7 anther, dorsal view 8 anther, lateral view; all after Droissart & Juswara 1735. Single scale bar = 1 mm; double scale bar = 1 cm. Drawing: Judi Stone.
Figure 1 from: Juswara L, Schuiteman A, Droissart V (2016) Four new orchid species from the Lengguru fold belt, West Papua, Indonesia. PhytoKeys 61: 47-59. https://doi.org/10.3897/phytokeys.61.7590
Figure 1 - Main localities sampled during Lengguru 2014 expedition and distribution of the four new species in West Papua, Indonesia.
Figure 3 from: Juswara L, Schuiteman A, Droissart V (2016) Four new orchid species from the Lengguru fold belt, West Papua, Indonesia. PhytoKeys 61: 47-59. https://doi.org/10.3897/phytokeys.61.7590
Figure 3 - Photographs of living type specimens and habitats. Bulbophyllum leucoglossum: A habitat and habit B flower, side view C flower, front view D Flower close-up, showing details of the column and the labellum. Dendrobium centrosepalum: E habitat and habit F, G plant and inflorescence H inflorescence and flowers close-up. Photos: Vincent Droissart.
Data files used in the paper "First Radar Evidence of Large-Scale Englacial Folding in the South Polar Layered Deposits (Ultimi Scopuli, Mars) and Possible Ice Sheet Flow Unveiled by MARSIS" By Guallini et al.
<p>This archive contains radargrams, geometric information and visualizations of a subset of MARSIS radar observations over Planum Australe, Mars. This archive contains everything needed to reproduce the results presented in the paper "Large-scale folds detected by MARSIS in the Southern ice sheet of Ultimi Scopuli (Mars)" by Guallini et al.</p> <p>Three types of MARSIS data files are contained in this archive:</p> <p>* orbit_XXXXX_frequency_Y_MHz_radargram.csv, where XXXXX is the orbit number, and Y the frequency at which the radar was operating, in MHz. The file contains an ASCII table of real numbers separated by commas. The table has as many columns as the number of radar echoes acquired during the orbit (usually 3200), and 980 lines, one for each echo sample. Values are samples of the uncalibrated echo voltage, without phase information (i.e. positive real numbers instead of complex echo samples). Echo samples are acquired every 0.3571 microseconds (2.8 MHz sampling rate). The first sample of an echo is located at a round-trip time corresponding to an altitude of 25 km above the Martian IAU ellipsoid.</p> <p>* orbit_XXXXX_frequency_Y_MHz_geometry.csv, where XXXXX is the orbit number, and Y the frequency at which the radar was operating, in MHz. The file contains an ASCII table of real numbers separated by commas. The table has as many rows as the number of radar echoes acquired during the orbit (usually 3200), and contains the following auxiliary parameters:</p> <p> - EPHEMERIS TIME - Number of seconds elapsed since Jan 1, 2000, 12:00 UTC corresponding to the time at which data collection for the current echo started.</p> <p> - MARS SOLAR LONGITUDE - Angle between the Mars-Sun line at the time corresponding to EPHEMERIS TIME and the Mars-Sun line at the vernal equinox, in degrees.</p> <p> - MARS SUN DISTANCE - Distance from the centre of Mars to centre of the Sun at the time corresponding to EPHEMERIS TIME, in Km.</p> <p> - SPACECRAFT ALTITUDE - Distance from the Mars Express spacecraft to the reference surface of the target body measured normal to the surface at the time corresponding to EPHEMERIS TIME, expressed in Km.</p> <p> - SUB-SPACECRAFT LONGITUDE - East longitude of the point on the target body that lies closest to the Mars Express spacecraft at the time corresponding to EPHEMERIS TIME, expressed in degrees and in the [ 0 -360 ] range.</p> <p> - SUB-SPACECRAFT LATITUDE - Planetocentric latitude of the point on the target body that lies directly beneath the Mars Express spacecraft at the time corresponding to EPHEMERIS TIME, expressed in degrees.</p> <p> - RADIAL VELOCITY - Radial component of the Mars Express spacecraft velocity vector in the reference frame of the target body at the time corresponding to EPHEMERIS TIME, expressed in Km/s.</p> <p> - TANGENTIAL VELOCITY - Tangential component of the Mars Express spacecraft velocity vector in the reference frame of the target body at the time corresponding to EPHEMERIS TIME, expressed in Km/s.</p> <p> - LOCAL TRUE SOLAR TIME - Angle between the extension of the vector from the Sun to Mars and the projection on Mars' ecliptic plane of a vector from the center of the target body and the point on the target body surface that lies directly beneath the Mars Express spacecraft at the time corresponding to EPHEMERIS TIME, expressed on a 24-hour clock with decimal fractions of the hour.</p> <p>* orbit_XXXXX_frequency_Y_MHz.png, where XXXXX is the orbit number, and Y the frequency at which the radar was operating, in MHz. The file is a visualization of the corresponding radargram, of the spacecraft ground track during the observation, and of surface and subsurface echo power.</p>
Text-fig. 16. Scanning electron microscope (SEM) images of "Stamen fragments with in situ Clavatipollenites- or Asteropollis-type pollen" (sp. 1: a–c; sp. 2: d–f; sp. 3: g–i); Catefica locality, Portugal. a) Stamen fragment showing pollen sacs; b) Distal view of pollen grain from (a) showing semitectate-reticulate tectum; c) Detail of pollen wall showing the semitectate-reticulate tectum and long, scattered, columellae supporting muri with fine pits and rounded supratectal ornamentation; note orbiculae with a finely spiny surface (arrows); d) Stamen showing very short filament, lateral pollen sacs and short apical extension of the narrow connective; e) Folded pollen grain from (d) showing semitectate-reticulate tectum; f) Detail of pollen wall from (d) showing the semitectatereticulate tectum and muri with fine rounded ornamentation; g) Stamen fragment; h, i) Detail of pollen grains from (g) showing the semitectate-reticulate tectum with smooth muri, long scattered columellae and tiny scattered orbicules (arrow). Specimens, Catefica 50-S170395 (a–c), Catefica 49-S172561 (d–f), Catefica 50-S170390 (g–i). Scale bars = 600 Μm (a, d, g), 6 Μm (b, e, h), 1.5 Μm (c, f, i). in The Early Cretaceous Mesofossil Flora Of Catefica, Portugal: Angiosperms
Text-fig. 16. Scanning electron microscope (SEM) images of "Stamen fragments with in situ Clavatipollenites- or Asteropollis-type pollen" (sp. 1: a–c; sp. 2: d–f; sp. 3: g–i); Catefica locality, Portugal. a) Stamen fragment showing pollen sacs; b) Distal view of pollen grain from (a) showing semitectate-reticulate tectum; c) Detail of pollen wall showing the semitectate-reticulate tectum and long, scattered, columellae supporting muri with fine pits and rounded supratectal ornamentation; note orbiculae with a finely spiny surface (arrows); d) Stamen showing very short filament, lateral pollen sacs and short apical extension of the narrow connective; e) Folded pollen grain from (d) showing semitectate-reticulate tectum; f) Detail of pollen wall from (d) showing the semitectatereticulate tectum and muri with fine rounded ornamentation; g) Stamen fragment; h, i) Detail of pollen grains from (g) showing the semitectate-reticulate tectum with smooth muri, long scattered columellae and tiny scattered orbicules (arrow). Specimens, Catefica 50-S170395 (a–c), Catefica 49-S172561 (d–f), Catefica 50-S170390 (g–i). Scale bars = 600 Μm (a, d, g), 6 Μm (b, e, h), 1.5 Μm (c, f, i).
Figure datafiles for Network of hotspot interactions cluster tau amyloid folds
<p>Datafiles used to produce the figures for</p> <p>Network of hotspot interactions cluster tau amyloid folds</p>
single-molecule tertiary structure determination reveals RNA folding landscape
<p>Initial release of the 6HB RNA origami 3D density maps, fitting models and EMDB validation reports.</p>
The structural landscape of the immunoglobulin fold by large-scale de novo design
<p>Dataset for the high-quality immunoglobulin designs.</p>
Emervel Classic Lidocaine Versus Juvederm® Ultra in Treatment of Moderate to Severe Facial Wrinkles and Folds
ClinicalTrials.gov study NCT01205048. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of the Improvement of Quality of Life of Patients Suffering From Hailey Hailey or Darier Disease After Injections of Botulism Toxin Into Large Folds.
ClinicalTrials.gov study NCT02782702. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds
ClinicalTrials.gov study NCT01066026. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.