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Dataset results
684 results for “influenza A virus”
IF001 - Microarray analysis from ferret infections with highly pathogenic reconstructed H1N1 1918 influenza virus.
GEO Series GSE49060. Mustela putorius furo. 16 samples. Type: Expression profiling by array.
Identification of lncRNA-up4 as an Enhancer of Influenza A Virus Replication through Negatively Regulating the Innate Immune Response
GEO Series GSE279270. Gallus gallus. 6 samples. Type: Expression profiling by high throughput sequencing.
Human Calu-3 cell transcriptome response to a wild type infectious clone of H5N1 Influenza virus and mutant H5N1 viruses [mRNA]
GEO Series GSE76599. Homo sapiens. 80 samples. Type: Expression profiling by array.
Data from: Host interaction analysis of PA-N155 and PA-N182 in chicken cells reveals an essential role of UBA52 for replication of H5N1 avian influenza virus
PA-N155 and PA-N182 proteins were translated from the 11th and 13th start codon AUG of the RNA polymerase acidic protein (PA) mRNA of H5N1 influenza A virus (IAV), which plays an important role in viral replication. Little is known about the interactions between PA-N155 and PA-N182 and the host proteins. This study investigated the interaction landscape of PA-N155 and PA-N182 of H5N1 IAV in chicken cells while their interacting complexes were captured by immunoprecipitation and analyzed by mass spectrometry. A total of 491 (PA-N155) and 302 (PA-N182) interacting proteins were identified. Gene ontology and pathway enrichment analyses showed that proteins of the two interactomes were enriched in RNA processing, viral processing and protein transport, and proteins related to signaling pathways of proteasome, ribosome, and aminoacy1-tRNA biosynthesis were significantly enriched, suggesting their potential roles in H5N1 IAV infection. Comparative analysis of the interactome of PA, PA-N155, and PA-N182 identified UBA52 as a conserved host factor that interacted with all three viral proteins. UBA52 is a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus. Knockdown of UBA52 significantly decreased the titer of H5N1 IAV in chicken cells and was accompanied with attenuated production of proinflammatory cytokines. Our analyses of the influenza–host protein interactomes identified UBA52 as a PA interaction protein for virus replication.
Study of Influenza Virus Infection in Children Hospitalized in Spain in Two Consecutive Influenza Seasons
ClinicalTrials.gov study NCT04008823. IPD Sharing: NO. Countries: 1. Publications: 0.
Safety and Efficacy Study of Inhaled PUR003 on a Controlled Influenza Virus Challenge in Healthy Adult Subjects
ClinicalTrials.gov study NCT00947687. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of DNA Vaccine With Electroporation for the Prevention of Disease Caused by H1 and H5 Influenza Virus
ClinicalTrials.gov study NCT01405885. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Virosensor -Based Real-time Diagnosis of Enterovirus 71 and Influenza Virus
ClinicalTrials.gov study NCT02009735. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficiency of Antagonist Drugs of the Cellular Transcriptomic Signature of Influenza A Virus Infection.
ClinicalTrials.gov study NCT03212716. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of the Safety, Tolerability & Immunogenicity of CSL Limited's Influenza Virus Vaccine In a Paediatric Population
ClinicalTrials.gov study NCT00700193. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Phase I Study Priming With an Inactivated A/H7N9 Influenza Virus Vaccine With or Without MF59 Adjuvant Followed by Live Attenuated A/H7N9 Influenza Virus Vaccine
ClinicalTrials.gov study NCT02251288. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Human Mucosal Immune Responses to Influenza Virus (SLVP026)
ClinicalTrials.gov study NCT03023553. IPD Sharing: YES. Countries: 0. Publications: 0.
A Clinical Trial of an Quadrivalent Influenza Virus Subunit Vaccine in Chinese Children Aged 6 to 35 Months
ClinicalTrials.gov study NCT05645900. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults
ClinicalTrials.gov study NCT06382311. IPD Sharing: YES. Countries: 1. Publications: 0.
Single Ascending Dose Challenge Study to Determine Safety and Reactogenicity of an Influenza Challenge Virus
ClinicalTrials.gov study NCT04106817. IPD Sharing: NO. Countries: 0. Publications: 0.
A Safety, Reactogenicity, and Immunogenicity Study of mRNA-1045 (Influenza and Respiratory Syncytial Virus [RSV]) or mRNA-1230 (Influenza, RSV, and Severe Acute Respiratory Syndrome Coronavirus 2 [SAR
ClinicalTrials.gov study NCT05585632. IPD Sharing: Not stated. Countries: 3. Publications: 0.
BPL-1357 Against H1N1 Influenza Virus Challenge
ClinicalTrials.gov study NCT07215858. IPD Sharing: NO. Countries: 1. Publications: 0.
Extra-pulmonary Clinical Manifestations of Influenza Virus and Respiratory Syncitial Virus Infections
ClinicalTrials.gov study NCT03757546. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Evaluate the Safety and Immunogenicity of Pandemic Monovalent (H5N1) Influenza Vaccines (Whole Virus Formulation) in Adults 18 and 60 Years of Age
ClinicalTrials.gov study NCT00309647. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Trial to Compare the Safety, Tolerability, Immunogenicity and Efficacy of Three Dose Levels of a Liquid Formulation of Influenza Virus Vaccine, (CAIV-T) in Healthy Children
ClinicalTrials.gov study NCT00192374. IPD Sharing: Not stated. Countries: 2. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.