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15,247 results for “Breast cancer”
breast cancer dataset
<p>This is a dataset of breast cancer patients</p>
Polymorphisms In A Cytokine Receptor And A Cytokine Regulator Are Associated With Levels Of Exercise In Women Prior To Breast Cancer Surgery
<p>This dataset contains the supplementary materials describing in detail the methods and the results of the analyses. The manuscript has been accepted for publication. Please cite both the paper as well as the DOI of this dataset if you make use of the data.</p>
Liquid Biopsy as a Diagnostic and Prognostic Tool for Women and Female Dogs with Breast Cancer
<p>This dataset contains numerous analyses on genetic variants obtained from liquid biopsy of women and dogs with breast cancer (BC). Both core biopsy and plasma samples were processed for next generation sequencing (NGS) assay. The effectiveness of liquid biopsy in the diagnosis and follow-up of women and female dogs with BC was investigated. In this study, 55 and 35 BC samples were collected from women and female dogs, respectively. After obtaining core biopsy and plasma samples, DNA and ctDNA of tumor fragments and plasma were processed and submitted to the Genome Analysis ToolKit (GATK).</p> <p> </p>
Figure 6 from: AlMotwaa SM (2021) Coupling Ifosfamide to nanoemulsion-based clove oil enhances its toxicity on malignant breast cancer and cervical cancer cells. Pharmacia 68(4): 779-787. https://doi.org/10.3897/pharmacia.68.e68291
Figure 6 Relative fluorescence intensity of nuclei at various concentrations of the studied formulas analyzed using Image J 1.43. Data are expressed as mean ± SE (n=3). Asterisks denote statistical significance (***p < 0.001 considered as very highly significant, **0.001 ≤ p < 0.01 considered as highly significant, and *0.01 ≤p < 0.05 considered as significant).
Figure 5 from: AlMotwaa SM (2021) Coupling Ifosfamide to nanoemulsion-based clove oil enhances its toxicity on malignant breast cancer and cervical cancer cells. Pharmacia 68(4): 779-787. https://doi.org/10.3897/pharmacia.68.e68291
Figure 5 Fluorescence microscopic images of changes in nuclear morphology of MCF-7 cells treated with various concentrations of the tested formulas for 24h, as revealed using DAPI stain (n = 3).
Figure 4 from: AlMotwaa SM (2021) Coupling Ifosfamide to nanoemulsion-based clove oil enhances its toxicity on malignant breast cancer and cervical cancer cells. Pharmacia 68(4): 779-787. https://doi.org/10.3897/pharmacia.68.e68291
Figure 4 Fluorescence microscopic images of changes in nuclear morphology of HeLa cells treated with various concentrations of the tested formulas for 24h, as revealed using DAPI stain (n = 3).
Figure 2 from: AlMotwaa SM (2021) Coupling Ifosfamide to nanoemulsion-based clove oil enhances its toxicity on malignant breast cancer and cervical cancer cells. Pharmacia 68(4): 779-787. https://doi.org/10.3897/pharmacia.68.e68291
Figure 2 Cell viability of HeLa and MCF-7 cells after 24h of incubation with clove oil-based NE at various concentrations. Data are expressed as mean ± SE (n = 3). Asterisks denote statistical significance (***p < 0.001 considered as very highly significant, **0.001 ≤ p < 0.01 considered as highly significant, and *0.01 ≤ p < 0.05 considered as significant).
Figure 3 from: AlMotwaa SM (2021) Coupling Ifosfamide to nanoemulsion-based clove oil enhances its toxicity on malignant breast cancer and cervical cancer cells. Pharmacia 68(4): 779-787. https://doi.org/10.3897/pharmacia.68.e68291
Figure 3 Photomicrographs of cellular morphologies at IC50 after 24 h incubation (n=3). The arrows colored brown, green, red, black, and dark red indicate membrane blebbing, cytoplasmic vesicles, enlarged nuclei, loss of membrane integrity, and extracellular vesicles, respectively.
Figure 1 from: AlMotwaa SM (2021) Coupling Ifosfamide to nanoemulsion-based clove oil enhances its toxicity on malignant breast cancer and cervical cancer cells. Pharmacia 68(4): 779-787. https://doi.org/10.3897/pharmacia.68.e68291
Figure 1 Preparation and characterization of clove oil-based NE. A preparation of formulated NEsB, C Z-average diameter (n=3); D, E Zeta potential for n=3 using Zetasizer Malvern, UK). Asterisks denote statistical significance (**0.001 ≤ p < 0.01 considered as highly significant, and *0.01 ≤ p < 0.05 considered as significant).
Spatial profile of tumor microenvironment in PD-L1-negative and PD-L1-positive triple negative breast cancer
<p><strong>Supplementary Materials</strong></p>
A Dataset of Annotated Histopathological Images for Tumor Cellularity Assessment in Breast Cancer
<p>The dataset consists of 2 H&E whole slide images, captured at a magnification of 40×, which overall contains tens of thousands of tumor nuclei from patients with breast cancer. The annotations, which consist of tumor and non-tumor nuclei, were provided by an expert pathologist, using the QuPath software. In detail, within the indicated ROIs, 1419 tumor-nuclei and 605 non-tumor-nuclei were labeled for a total of 2024 nuclei (respectively 762 and 381 from the first WSI, 657 and 224 from the second WSI).</p> <p>The institutional Ethic Committee of the IRCCS Istituto Tumori Giovanni Paolo II approved the study -- Prot n. 8/CE (February 2, 2021).</p>
BRD8 is a therapeutic vulnerability for overcoming resistance to dual ER/HER2 blockade therapy in HR+/HER2+ breast cancer
<p>.rda file for Seurat object of scRNA-seq data from BT474 breast cancer cell lines treated with DMSO, Neratinib, Fulvestrant, and a combination of Neratinib and Fulvestrant.</p>
RNA-seq gene expression profiles from female ER-positive HER2-normal breast cancer patients
<p>Diagnostic samples (<em>n</em> = 59) from female breast cancer patients with ER-positive and HER2-normal tumors selected for neoadjuvant chemotehrapy.<br> </p> <p><strong>Data contents</strong></p> <table> <tbody> <tr> <td>README.txt</td> <td>README file</td> </tr> <tr> <td>meta_mat.tsv</td> <td>Metadata table</td> </tr> <tr> <td>expr_mat_probes.tsv.gz</td> <td>Expression matrix with probeset identifiers</td> </tr> <tr> <td>expr_mat_genes.tsv.gz</td> <td>Expression count matrix with gene identifiers</td> </tr> </tbody> </table>
Contrastive learning-based histopathological feature infers molecular subtypes and clinical outcomes of breast cancer from unannotated whole slide images
<p>The breast cancer cohort came from the Changzhou Second People's Hospital (CZSPH) in Jiangsu, China. This cohort collected 91 FFPE WSIs from 90 breast cancer patients, including 15 recurrence cases within 5 years.</p>
Supplemental Data for "Riluzole suppresses growth and enhances response to endocrine therapy in ER+ breast cancer"
<p>Supplemental Figures and Legends for Olukoya et al 2023 (https://doi.org/10.1101/2020.07.30.227561)</p>
Fig. 4 in Isoquinoline alkaloids from Hylomecon japonica and their potential anti-breast cancer activities
Fig. 4. Experimental and calculated ECD spectra of compounds 1–4.
Fig. 2 in Isoquinoline alkaloids from Hylomecon japonica and their potential anti-breast cancer activities
Fig. 2. Key HMBC (arrows) and 1H–1H COSY (bold) correlations of compounds 1–9.
Spatial Transcriptomic Experiment of Triple-Negative Breast Cancer PDX Model PIM001-P model treatment naive sample
<p>Spatial Transcriptomic Experiment of Triple-Negative Breast Cancer PDX Model PIM001-P model treatment naive sample</p> <p>10X Genomics Visium platform. </p> <p><strong>Library Preparation and Sequencing of PIM001P</strong></p> <p>Tissue sections of 10µm thickness were mounted onto the capture areas of the Visium Spatial Gene Expression slide and stained using hematoxylin and eosin. Tissue sections were permeabilized on a thermocycler for 24 minutes, as determined by the Tissue Optimization step. Poly-adenlyated mRNA is released and captured by surface-bound primers within each capture area. Reverse transcription, template switching, extension, and second strand synthesis are performed on the slide. Full-length, spatially barcoded cDNA transcripts are then denatured from the slide and amplified via PCR prior to library construction. Approximately 110 to 375 ng of amplified cDNA was carried forward into library construction. During library construction, cDNA is enzymatically fragmented to target amplicon size then undergoes end repair, A-tailing, adapter ligation, and then amplified using between 14 and 16 PCR cycles. The resulting libraries were quantitated using the Invitrogen Qubit 2.0 quantitation assay and fragment size assessed with the Agilent Bioanalyzer. A qPCR quantitation was performed on the libraries to determine the concentration of adapter ligated fragments using Applied Biosystems ViiA7 Real-Time PCR System and a KAPA Library Quant Kit (p/n KK4824). All samples were pooled equimolarly and re-quantitated by qPCR, and also re-assessed on the Bioanalyzer.</p> <p><strong>Sequencing: </strong></p> <p>150 pM of equimolarly pooled library was loaded onto the NovaSeq 6000 S4 flowcell and sequenced at the recommended 28-10-10-50 read configuration. PhiX Control v3 adapter-ligated library (Illumina p/n FC-110-3001) was spiked-in at 2% by weight to ensure balanced diversity and to monitor clustering and sequencing performance. A minimum of 300 million read pairs per sample was sequenced. FastQ file generation was executed using 10X Genomics’ Space Ranger mkfastq software.</p> <p> </p>
Radiomics and Artificial Intelligence Analysis by T2 weighted imaging and Dynamic Contrast Enhanced Magnetic resonance imaging to predict Breast Cancer Histological Outcome
<p>Radiomics features obtained by MR images to predict Breast Cancer Histological Outcome.</p>
Prediction of Breast Cancer Histological Outcome with Radiomics and Artificial Intelligence Analysis by Contrast-Enhanced Mammography
<p>Radiomic features on contrast-enhanced mammography (CEM) images</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.