Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Tissue-Engineered Disease Modeling of Lymphangioleiomyomatosis Exposes a Therapeutic Vulnerability to HDAC Inhibition
GEO Series GSE179044. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNAseq (10x Genomics) analysis of the abdominal aorta in a murine model of Kawasaki disease vasculitis
GEO Series GSE178765. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
A TrkB and TrkC partial agonist prevents synaptic plasticity deficits and elicits activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer’s disease mouse model
GEO Series GSE243110. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Maturation of human cardiac organoids enables complex disease modelling and drug discovery
GEO Series GSE287136. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Spatially-patterned and functional kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
GEO Series GSE262382. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Self-organizing human neuruloids allow disease modeling in the developing ectodermal compartment
GEO Series GSE118682. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
RNA-sequencing of brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington’s disease
GEO Series GSE194416. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Dietary Gluten-Induced Gut Dysbiosis is Accompanied by Selective Upregulation of microRNAs with Intestinal Tight Junction and Bacteria-Binding Motifs in Rhesus Macaque Model of Celiac Disease
GEO Series GSE89170. Macaca mulatta; Homo sapiens. 9 samples. Type: Expression profiling by RT-PCR.
The Impact of SIV-Induced Immunodeficiency on SARS-CoV-2 Disease, Viral Dynamics, and Antiviral Immune Response in a Nonhuman Primate Model of Coinfection
GEO Series GSE272713. Macaca nemestrina. 2 samples. Type: Expression profiling by high throughput sequencing.
Fibrotic and Immune Pathway Signatures in Systemic Sclerosis Suggest a Progressive, Multi-step Model of Disease Pathogenesis
GEO Series GSE56308. Homo sapiens. 94 samples. Type: Expression profiling by array.
Experimental mouse model of chronic kidney disease reveals altered cardiac oxidative stress responses in CKD
GEO Series GSE191122. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics data of blood and brain from the YAC128 Huntington's disease mouse model [brain]
GEO Series GSE170997. Mus musculus. 56 samples. Type: Expression profiling by high throughput sequencing.
NBL1 Correlates with Renal Phenotypes in Mouse Models of Kidney Disease, but is not Causal: Male Nbl1 HET or WT Mice Treated with Cisplatin or PBS
GEO Series GSE310628. Mus musculus. 31 samples. Type: Expression profiling by high throughput sequencing.
Pluripotent stem cell derived models of neurological diseases reveal early transcriptional heterogeneity
GEO Series GSE138525. Homo sapiens. 426 samples. Type: Expression profiling by high throughput sequencing.
A multi-omics approach using a mouse model of cardiac malformations for prioritization of human congenital heart disease contributing genes
GEO Series GSE171239. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [ChIP-seq]
GEO Series GSE127507. Homo sapiens. 26 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington’s disease
GEO Series GSE97101. Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing.
Single nucleus RNA-seq of brain regions showing high-low Abeta plaque pathology in a mouse model of Alzheimer’s disease
GEO Series GSE214244. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Genetic modifiers of GFAP expression in mouse models of Alexander disease
GEO Series GSE197044. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Molecular barcodes and single cell transcriptomics to map graft diversity and lineage of human DA neurons in a rat xenograft model of Parkinson’s Disease
GEO Series GSE200610. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.