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100 results for “ADME”
Open Label, Healthy Volunteers, ADME Study With Single Oral Administration of [14C] AZD5069
ClinicalTrials.gov study NCT01332903. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Human Genomic Population Structure and Phenotype-genotype Variation in ADME Genes in Four Populations
ClinicalTrials.gov study NCT02789527. IPD Sharing: UNDECIDED. Countries: 4. Publications: 1.
Healthy Volunteers, Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] AZD8931
ClinicalTrials.gov study NCT01284595. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fig. 7. Predicted Boiled-Egg plot from Swiss ADME online web tool for compounds 1–3 in Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAF and MEK 1 kinases via in-silico study and ADME prediction
Fig. 7. Predicted Boiled-Egg plot from Swiss ADME online web tool for compounds 1–3.
Fig. 1 in Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAF and MEK 1 kinases via in-silico study and ADME prediction
Fig. 1. Chemical structures of isolated compounds (1–11).
Fig. 3 in Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAF and MEK 1 kinases via in-silico study and ADME prediction
Fig. 3. Significant NOESY correlations of diterpenoids 1–3.
Fig. 2. Significant 1H 1H in Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAF and MEK 1 kinases via in-silico study and ADME prediction
Fig. 2. Significant 1H 1H COSY and HMBC correlations of diterpenoids 1–3.
Restoration® Anatomic Dual Mobility (ADM) X3® Acetabular System Study
ClinicalTrials.gov study NCT01420237. IPD Sharing: Not stated. Countries: 3. Publications: 0.
A Study in Healthy Adult Male Participants to Assess Absorption, Distribution, Metabolism and Excretion (ADME) of Radiolabeled PF-06865571.
ClinicalTrials.gov study NCT04866225. IPD Sharing: NO. Countries: 1. Publications: 0.
Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects
ClinicalTrials.gov study NCT05737433. IPD Sharing: Not stated. Countries: 1. Publications: 0.
BI 6727 (Volasertib) Human ADME Trial in Various Solid Tumours
ClinicalTrials.gov study NCT01145885. IPD Sharing: Not stated. Countries: 1. Publications: 0.
An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors
ClinicalTrials.gov study NCT05976334. IPD Sharing: NO. Countries: 1. Publications: 0.
Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C]-BI 207127 in Healthy Male Volunteers
ClinicalTrials.gov study NCT01605461. IPD Sharing: Not stated. Countries: 1. Publications: 0.
CPEX-AW ADM-Aeolus Datasets
CPEXAW-ADM-Aeolus_1 is the ESA ADM-Aeolus Datasets for the Convective Processes Experiment - Aerosols & Winds (CPEX-AW) sub-orbital campaign. Data collection for this product is complete.The Convective Processes Experiment – Aerosols & Winds (CPEX-AW) campaign was a joint effort between the US National Aeronautics and Space Administration (NASA) and the European Space Agency (ESA) with the primary goal of conducting a post-launch calibration and validation activities of the Atmospheric Dynamics Mission-Aeolus (ADM-AEOLUS) Earth observation wind Lidar satellite in St. Croix. CPEX-AW is a follow-on to the Convective Processes Experiment (CPEX) field campaign which took place in the summer of 2017. In addition to joint calibration/validation of ADM-AEOLUS, CPEX-AW studied the dynamics related to the Saharan Air Layer, African Easterly Waves and Jets, Tropical Easterly Jet, and deep convection in the InterTropical Convergence Zone (ITCZ). CPEX-AW science goals include:• Better understanding interactions of convective cloud systems and tropospheric winds as part of the joint NASA-ESA Aeolus Cal/Val effort over the tropical Atlantic;• Observing the vertical structure and variability of the marine boundary layer in relation to initiation and lifecycle of the convective cloud systems, convective processes (e.g., cold pools), and environmental conditions within and across the ITCZ;• Investigating how the African easterly waves and dry air and dust associated with Sahara Air Layer control the convectively suppressed and active periods of the ITCZ;• Investigating interactions of wind, aerosol, clouds, and precipitation and effects on long range dust transport and air quality over the western Atlantic.In order to successfully achieve the objectives of the campaign, NASA deployed its DC-8 aircraft equipped with an Airborne Third Generation Precipitation Radar (APR-3), Doppler Aerosol WiNd Lidar (DAWN), High Altitude Lidar Observatory (HALO), High Altitude Monolithic Microwave Integrated Circuit (MMIC) Sounding Radiometer (HAMSR), and dropsondes. This campaign aims to provide useful material to atmospheric scientists, meteorologists, lidar experts, air quality experts, professors, and students. The Atmospheric Science Data Center (ASDC) archives the dropsonde, HALO, and DAWN data products for CPEX-AW. For additional datasets please visit the Global Hydrometeorology Resource Center (GHRC).
Transcription profiling of atm mutant adm mutant and wild type whole plants and roots of Arabidopsis after gamma ray irradiation in a time series
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and atr (4d) mutants have been analyzed after a 1h irradiation. Ataxia Telangiectasia Mutated (ATM) encodes a large protein with a phosphatidylinositol 3-kinase (PI3K)-like domain at the C terminus (reviewed by Rotman and Shiloh 1998). PI3K-related proteins make up a large family of Ser-Thr protein kinases numerous members of which are involved in the regulation of cell cycle progression responses to DNA damage and the maintenance of genomic stability (Hoekstra 1997). AtATM plays an essential role in meiosis and in the somatic response to DNA damage in plants similar to the function of ATM in mammals and other eukaryotes. Ataxia telangiectasia-mutated and Rad3-related (ATR) plays a central role in cell-cycle regulation transmitting DNA damage signals to downstream effectors of cell-cycle progression.
miRNA profiles of adipocyte-derived microvesicles (ADMs)
GEO Series GSE17977. Mus musculus. 2 samples. Type: Non-coding RNA profiling by array.
Murine 3T3-L1 adipocytes vs. adipocyte-derived microvesicles (ADMs)
GEO Series GSE17973. Mus musculus. 2 samples. Type: Expression profiling by array.
14-C ADME (Absorption, Disposition, Metabolism and Excretion) Study in Man
ClinicalTrials.gov study NCT01176201. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Investigate ADME of 14C Labeled SLV334 After an i.v. Infusion
ClinicalTrials.gov study NCT01044524. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparative Efficacy of ADM Hydrogel vs. Alginate Dressings in Chronic Trauma Wounds
ClinicalTrials.gov study NCT06978569. IPD Sharing: YES. Countries: 1. Publications: 0.
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International Brain Laboratory public data
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OpenNeuro
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