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106 results for “BRAF inhibitors”

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ClinicalTrials.gov28/100

Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or Trametinib

ClinicalTrials.gov study NCT02314143. IPD Sharing: Not stated. Countries: 2. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

BRAF Inhibitor, LGX818, Utilizing a Pulsatile Schedule in Patients With Stage IV or Unresectable Stage III Melanoma Characterized by a BRAFV600 Mutation

ClinicalTrials.gov study NCT01894672. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With t

ClinicalTrials.gov study NCT01726738. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo24/100

Targeted radionuclide therapy for pigmented BRAF- and NRAS-mutated melanoma: [131I]ICF01012 efficacy and combination with MAPK/ERK pathway inhibitors

GEO Series GSE162536. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2021View details →
geo24/100

Gene and microRNA expression profiling of a melanoma cell line resistant to BRAF inhibitor PLX4032 compared to the parental sensitive counterpart (miRNA)

GEO Series GSE68839. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenFeb 2016View details →
geo24/100

RNA-Seq analysis (long-reads) of human parental M238P and BRAF inhibitors-resistant M238R melanoma cells

GEO Series GSE171882. Homo sapiens. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenDec 2021View details →
geo24/100

SmallRNAome profile of melanoma cell lines A375 and A375-BIR (BIR-BRAF INHIBITOR RESISTANT) during dabrafenib treatment

GEO Series GSE165335. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

Trascriptional profile of BRAF inhibitor-resistant SKMEL28 and WM3248 melanoma cells and changes upon YAP/TAZ siRNA knockdown

GEO Series GSE68599. Homo sapiens. 16 samples. Type: Expression profiling by array.

openGEO-OpenNov 2015View details →
geo24/100

MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma

GEO Series GSE109378. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2019View details →
geo24/100

Gene expression profiles of matched pre- and post-treatment melanoma metastasis from seven patients treated with BRAF inhibitors (BRAFi)

GEO Series GSE141484. Homo sapiens. 14 samples. Type: Expression profiling by array.

openGEO-OpenOct 2020View details →
geo24/100

SAKE (Single-cell RNA-Seq Analysis and Klustering Evaluation) Identifies Markers of Resistance to Targeted BRAF Inhibitors in Melanoma Cell Populations [10x]

GEO Series GSE108394. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2018View details →
geo24/100

Transcriptome profile of melanoma cell lines A375 and A375-BIR (BIR-BRAF INHIBITOR RESISTANT) during dabrafenib treatment

GEO Series GSE165334. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

Selective inhibition of BRAF and CRAF sensitizes NF1-deficient malignant peripheral nerve sheath tumors to MEK inhibitors

GEO Series GSE303418. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation

GEO Series GSE74729. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2016View details →
geo24/100

Second-generation BRAF inhibitor Encorafenib resistance is regulated by NCOA4-mediated iron trafficking in the drug-resistant malignant melanoma cells

GEO Series GSE283251. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo24/100

Spectrum, clinical correlates and clinical implications of BRAF-inhibitor resistance mechanisms in melanoma

GEO Series GSE50509. Homo sapiens. 61 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2014View details →
geo24/100

Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF mutant thyroid carcinomas.

GEO Series GSE37441. Homo sapiens. 24 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2013View details →
geo24/100

Acquired resistance to BRAF-inhibitors restores melanoma tumor immune suppression

GEO Series GSE79206. Mus musculus. 16 samples. Type: Expression profiling by array.

openGEO-OpenMar 2017View details →
geo24/100

Transcriptomic profile of melanoma clinical samples treated with BRAF and MEK- inhibitors

GEO Series GSE165337. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

Divergent BRAF Inhibitor Resistance Mechanisms Revealed through Epigenetic Mapping

GEO Series GSE203546. Homo sapiens. 48 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenMay 2022View details →

ScienceDex guides

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record