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74 results for “BioTransformer”
Fig. 1 in Biotransformation of androstenedione and androstadienedione by selected Ascomycota and Zygomycota fungal strains
Fig. 1. AD and ADD structural modifications catalyzed by selected filamentous fungi: 1, 7β-hydroxylation; 2, 7α-hydroxylation; 3, 11α-hydroxylation; 4, 14α- hydroxylation; 5, 17-keto-reduction; 6, 1(2)-dehydrogenation; 7, 1(2)-hydrogenation.
Mass Balance, Pharmacokinetics, Biotransformation and Bioavailability Study of ODM-201 in Healthy Male Subjects
ClinicalTrials.gov study NCT02418650. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Where is the Initial Site of Biotransformation of Folates in Humans?
ClinicalTrials.gov study NCT02135393. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans
ClinicalTrials.gov study NCT05883306. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Mass Balance and Biotransformation of [14C]HSK7653 in Human
ClinicalTrials.gov study NCT04540016. IPD Sharing: NO. Countries: 1. Publications: 0.
Study on the Body Mass Balance and Biotransformation of [14C]-HEC585
ClinicalTrials.gov study NCT05468346. IPD Sharing: NO. Countries: 1. Publications: 6.
Data from: Fungal endophytes of Vanilla planifolia across Réunion Island: isolation, distribution and biotransformation.
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Data from: Biotransformation of chlorothalonil by strain Stenotrophomonas acidaminiphila BJ1 isolated from farmland soil
The chlorothalonil is a widely used fungicide while the contamination of soil and water environments by this chemical causes potential threats to the biodiversity. Given the metabolic potential of soil microorganisms, there is a need for developing microbiological approaches to degrade persistent compounds, such as chlorothalonil, in the contaminated sites. Here in this study, we isolated a bacterial strain (namely, BJ1) capable of degrading chlorothalonil from a chlorothalonil-contaminated farmland soil in the Shandong Province, China. Using 16S rDNA gene sequencing, morphological and biological characteristics, we identified the strain BJ1 as Stenotrophomonas acidaminiphila. The strain BJ1 utilizes chlorothalonil as a sole carbon source. At initial concentrations of 50, 100, 200, 300 mg l-1, it degraded 91.5%, 89.4%, 86.5 and 83.5% of chlorothalonil after 96 h of inoculation under optimum conditions (30 °C and pH 7.0), respectively. Two metabolites, methyl-2, 5, 6-trichloro-3-cyano-4-methoxy-benzoate and methyl-3- cyano-2, 4, 5, 6-tetrachlorobenzoate, were detected and identified based on HPLC-MS analysis, which suggests that the strain BJ1 metabolized chlorothalonil through the hydroxylation of chloro-group and hydration of cyano-group. The results of this study highlight the great potential for this bacterium to be used in chlorothalonil pollution remediation.
Supporting data to Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants
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Fig. 2 in Biotransformation of betulinic acid by Circinella muscae and Cunninghamella echinulata to discover anti-inflammatory derivatives
Fig. 2. Key COSY and HMBC correlations of metabolites 2, 4, and 8.
Fig. 1 in Biotransformation of betulinic acid by Circinella muscae and Cunninghamella echinulata to discover anti-inflammatory derivatives
Fig. 1. Biotransformation of betulinic acid by C. muscae and C. echinulata.
Fig. 3 in Biotransformation of betulinic acid by Circinella muscae and Cunninghamella echinulata to discover anti-inflammatory derivatives
Fig. 3. Key NOESY correlationships of metabolites 2 and 8.
Fig. 3. Key NOSEY correlations for metabolites 1–4 in Biotransformation of artemisinic acid to bioactive derivatives by endophytic Penicillium oxalicum B4 from Artemisia annua L.
Fig. 3. Key NOSEY correlations for metabolites 1–4.
Fig. 2. Key HMBC and 1H-1H COSY correlations for metabolites 1–5 in Biotransformation of artemisinic acid to bioactive derivatives by endophytic Penicillium oxalicum B4 from Artemisia annua L.
Fig. 2. Key HMBC and 1H-1H COSY correlations for metabolites 1–5.
Fig. 1 in Biotransformation of artemisinic acid to bioactive derivatives by endophytic Penicillium oxalicum B4 from Artemisia annua L.
Fig. 1. Structures of artemisinic acid (AA) and its biotransformation metabolites 1–8.
Fig. 8 in Biotransformation of artemisinic acid to bioactive derivatives by endophytic Penicillium oxalicum B4 from Artemisia annua L.
Fig. 8. Proposed biotransformation process of artemisinic acid (AA) by Penicillium oxalicum B4.
Fig. 1. Important 1H–13C in Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a
Fig. 1. Important 1H–13C-HMBC correlations of metabolites 5 and 6.
Fig. 3 in Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a
Fig. 3. Structure of papaverine and its metabolite from different Fungi.
Fig. 1 in Biotransformation of xenobiotics by hairy roots
Fig. 1. Proposed approach of biotransformation of xenobiotics in soil and bioreactor systems.
) continued (4 Table in Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a
) continued (4 Table
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.