Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,960
datasets available to search
ShareScore release 0.9.0
Dataset results
1,960 results for “Cortex”
Data set for "Reward-based learning drives rapid sensory signals in medial prefrontal cortex and dorsal hippocampus necessary for goal-directed behavior"
<p>Data set for: Le Merre P, Esmaeili V, Charrière E, Galan K, Salin P-A, Petersen CCH, Crochet S (2018) Reward-based learning drives rapid sensory signals in medial prefrontal cortex and dorsal hippocampus necessary for goal-directed behavior. Neuron, https://doi.org/10.1016/j.neuron.2017.11.031</p> <p>There are 44 files in this data upload:<br> 1. '2018_LeMerre_Neuron.pdf' - this is a pdf version of the online publication.<br> 2. 'Chronic_LFP_data.mat' - this is a Matlab data structure, which contains all the chronic LFP data for the publication.<br> 3. 'Silicon_Probe_data.mat' - this is a Matlab data structure, which contains all the mPFC silicon probe recording data for the publication.<br> 4. 'Opto_Inactivation_data.mat' - this is a Matlab data structure, which contains all the optogenetic inactivation data for the publication.<br> 5. 'Mus_Inactivation_data.mat' - this is a Matlab data structure, which contains all the pharmacological (Muscimol) inactivation data for the publication.<br> 6. 'Learning_Days_Mtrx.mat' - this is a Matlab data file, which contains the selected training days analyzed for the Trained condition in the Detection Task.<br> 7. 'Exposed_Days_Mtrx.mat' - this is a Matlab data file, which contains the selected days analyzed for the Exposed condition in the Neutral Exposure.<br> 8. 'p_value_colormap.mat' - this is a Matlab data file, which contains the color map used to display the p value in the Matlab codes 'plot_fig2A_SEP_D1_vs_Trained.m'; 'plot_fig2B_Amplitude_D1_vs_Trained.m'; 'plot_fig3A_SEP_D1_vs_Exposed.m'; 'plot_fig4A_SEP_H_vs_M.m’.<br> 9. 'p_value_colormap2.mat' - this is a Matlab data file, which contains the color map used to display the p value in the Matlab code 'plot_figS3B_Stim_vs_Catch_for_significantly_inc_dec_units.m’; ’plot_figS4A_H_vs_M_for_inc_dec_units_and_zscored_PSTH.m’.<br> 10. 'scatterplot_colormap.mat' - this is a Matlab data file, which contains the color map used to display the p value in the Matlab code 'plot_fig2C_Scatterplot_Amplitude_vs_dprime.m'.<br> 11. 'SEP_colormtrx.mat' - this is a Matlab data file, which contains the color map used to display the p value in the Matlab code 'plot_fig1B_Sensory_Evoked_Potentials.m'; 'plot_figS3A_SEP_EMG_amplitude_ReactionTime.m'.<br> 12. 'zscore_colormap.mat' - this is a Matlab data file, which contains the color map used to display the p value in the Matlab code 'plot_fig3D_mPFC_PSTH_and_zscore_DT_vs_NE.m'; 'plot_figS4A_H_vs_M_for_inc_dec_units_and_zscored_PSTH.m’.<br> 13. 'Chronic_LFP_dataViewer.fig' - this is a Matlab Figure file, which is the GUI layout for 'Chronic_LFP_dataViewer.m'.<br> 14. 'Chronic_LFP_dataViewer.m' - this is a Matlab code, which displays the data contained in 'Chronic_LFP_data.mat'.<br> 15. 'Silicon_Probe_dataViewer.fig' - this is a Matlab Figure file, which is the GUI layout for 'Silicon_Probe_dataViewer.m'.<br> 16. 'Silicon_Probe_dataViewer.m' - this is a Matlab code, which displays the data contained in 'Silicon_Probe_data.mat'.<br> 17. 'plot_fig1B_Sensory_Evoked_Potentials.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results published in figure 1, panel B (Le Merre et al., 2018).<br> 18. 'plot_fig1C_Silicon_Probe_Hit_trials.m' - this is a Matlab code, which analyses the data in 'Silicon_Probe_data.mat', and displays the results in the same way as the published figure 1, panel C (Le Merre et al., 2018).<br> 19. 'plot_fig2A_SEP_D1_vs_Trained.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 2, panel A (Le Merre et al., 2018).<br> 20. 'plot_fig2B_Amplitude_D1_vs_Trained.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 2, panel B (Le Merre et al., 2018).<br> 21. 'plot_fig2C_Scatterplot_Amplitude_vs_dprime.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 2, panel C (Le Merre et al., 2018).<br> 22. 'plot_fig3A_SEP_D1_vs_Exposed.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 3, panel A (Le Merre et al., 2018).<br> 23. 'plot_fig3B_Amplitude_D1_vs_Exposed.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 3, panel B (Le Merre et al., 2018).<br> 24. 'plot_fig3C_ROC_Trained_vs_Exposed.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the ROCs in the same way as the published figure 3, panel C (Le Merre et al., 2018).<br> 25. 'plot_fig3C_ROC_Randomization.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the label shuffled ROCs in the same way as the published figure 3, panel C (Le Merre et al., 2018).<br> 26. 'plot_fig3D_mPFC_PSTH_and_zscore_DT_vs_NE.m' - this is a Matlab code, which analyses the data in 'Silicon_Probe_data.mat', and displays the results in the same way as the published figure 3, panel D (Le Merre et al., 2018).<br> 27. 'plot_fig4A_SEP_H_vs_M.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 4, panel A (Le Merre et al., 2018).<br> 28. 'plot_fig4B_Amplitude_ H_vs_M.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure 4, panel B (Le Merre et al., 2018).<br> 29. 'plot_fig4C_mPFC_PSTH_Hit_vs_Miss.m' - this is a Matlab code, which analyses the data in 'Silicon_Probe_data.mat', and displays the results in the same way as the published figure 4, panel C, left panel (Le Merre et al., 2018).<br> 30. 'plot_fig4C_Scatterplot_modulation_Hit_vs_Miss.m' - this is a Matlab code, which analyses the data in 'Silicon_Probe_data.mat', and displays the results in the same way as the published figure 4, panel C, right panel (Le Merre et al., 2018).<br> 31. 'plot_fig4D_Photoinhibitions.m' - this is a Matlab code, which analyses the data in 'Opto_Inactivation_data.mat', and displays the results published in figure 4, panel D (Le Merre et al., 2018).<br> 32. 'plot_figS2D_Performance_DetectionTask_NeutralExposition.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure S2, panel D (Le Merre et al., 2018).<br> 33. 'plot_figS3A_SEP_EMG_amplitude_ReactionTime.m' - this is a Matlab code, which analyses the data in 'Chronic_LFP_data.mat', and displays the results in the same way as the published figure S3, panel A (Le Merre et al., 2018).<br> 34. 'plot_figS3B_Stim_vs_Catch_for_significantly_inc_dec_units.m' - this is a Matlab code, which analyses the data in 'Silicon_Probe_data.mat', and displays the results in the same way as the published figure S3, panel B (Le Merre et al., 2018).<br> 35. 'plot_figS4A_H_vs_M_for_inc_dec_units_and_zscored_PSTH.m' - this is a Matlab code, which analyses the data in 'Silicon_Probe_data.mat', and displays the results in the same way as the published figure S4, panel A (Le Merre et al., 2018).<br> 36. 'plot_figS4B_Pharmacological_Inactivations.m' - this is a Matlab code, which analyses the data in 'Mus_Inactivation_data.mat', and displays the results published in figure S4 (Le Merre et al., 2018).<br> 37. 'Load_LFP_Multisite_database.m' - this is a Matlab code, which is called in the Matlab codes that analyze the data in 'Chronic_LFP_data.mat'.<br> 38. 'Load_Silicon_Probe_database.m' - this is a Matlab code, which is called in the Matlab codes that analyze the data in 'Silicon_Probe_data.mat'.<br> 39. 'Load_Optogenetic_Inactivation_database.m' - this is a Matlab code, which is called in the Matlab code that analyzes the data in 'Opto_Inactivation_data.mat'.<br> 40. 'Load_Pharmacological_Inactivation_database.m' - this is a Matlab code, which is called in the Matlab code that analyzes the data in 'Mus_Inactivation_data.mat'.<br> 41. 'bonf_holm.m' - this is a Matlab code developed by D. M. Groppe, which is called in the Matlab code 'plot_figS4B_Pharmacological_Inactivations.m':<br> https://ch.mathworks.com/matlabcentral/fileexchange/28303-bonferroni-holm-correction-for-multiple-comparisons<br> 42. 'boundedline.m' - this is a Matlab code developed by K. Kearney, which is called in the Matlab codes 'plot_fig1C_Silicon_Probe_Hit_trials.m'; 'plot_fig2A_SEP_D1_vs_Trained.m'; 'plot_fig3A_SEP_D1_vs_Exposed.m’; 'plot_fig3C_ROC_Trained_vs_Exposed.m'; 'plot_fig3D_mPFC_PSTH_and_zscore_DT_vs_NE.m'; 'plot_fig4A_SEP_H_vs_M.m'; 'plot_fig4C_mPFC_PSTH_Hit_vs_Miss.m'; 'plot_figS3B_Stim_vs_Catch_for_significantly_inc_dec_units.m'; 'plot_figS4A_H_vs_M_for_inc_dec_units_and_zscored_PSTH.m':<br> https://ch.mathworks.com/matlabcentral/fileexchange/27485-boundedline-m<br> 43. 'inpaint_nans.m' - this is a Matlab code, which is called in the Matlab code 'boundedline.m'.<br> 44. 'PSTH_Simple.m' - this is a Matlab code developed by V. Esmaeili, which is called in the Matlab codes 'plot_fig1C_Silicon_Probe_Hit_trials.m'; 'plot_fig3D_mPFC_PSTH_and_zscore_DT_vs_NE.m'; 'plot_fig4C_mPFC_PSTH_Hit_vs_Miss.m'; 'plot_figS3B_Stim_vs_Catch_for_significantly_inc_dec_units.m'; 'plot_figS4A_H_vs_M_for_inc_dec_units_and_zscored_PSTH.m’.</p>
The Human Developing Cerebral Cortex Is Characterized by an Elevated De Novo Expression of Long Noncoding RNAs in Excitatory Neurons
<p>This project contains the annotated transcriptomes in GTF format used in the manuscript "The Human Developing Cerebral Cortex Is Characterized by an Elevated De Novo Expression of Long Noncoding RNAs in Excitatory Neurons" DOI: <a href="https://doi.org/10.1093/molbev/msae123">https://doi.org/10.1093/molbev/msae123</a></p>
Prefrontal cortex activation and functional connectivity during human male orgasm measured with fNIRS
<p>A portable fNIRS system Brite MKII (Artinis, NE) was placed on the PFC of the self-experimenting participant (Male, 43 years). Ten sources and eight detectors are combined into 22 long separation channels (30mm) and two short-separation channels (SSC) to cover the PFC (Figure 1A). The experiment lasted 392s where the participant was subject to pornographic video clips (V) and performed genital self-stimulation (M) until orgasm was reached (O).<br>Citation of the article related to this dataset:</p> <div> <div><strong>Guevara, E.</strong> (2024). <em>Prefrontal cortex activation and functional connectivity during human male orgasm measured with fNIRS</em> [Preprint]. OSF. <a href="https://doi.org/10.31219/osf.io/6y2ze">https://doi.org/10.31219/osf.io/6y2ze</a></div> </div>
Functional Near-Infrared Spectroscopy Reveals Delayed Hemodynamic Changes in the Primary Motor Cortex During Fine Motor Tasks and Decreased Interhemispheric Connectivity in Parkinson's Disease Patients
<p>This dataset contains functional near-infrared spectroscopy (fNIRS) data from 20 patients with Parkinson’s disease and 20 age- and sex-matched healthy subjects without movement disorders. There are 3 folders, each corresponding to a different task: a 10-second finger-tapping task, a 2-minute walking task, and a 6-minute resting-state. When using this dataset, please cite our work:</p> <div> <div>Guevara, E., Rivas-Ruvalcaba, F. J., Kolosovas-Machuca, E. S., Ramírez-Elías, M., Zapata, R. D. de L., Ramirez-GarciaLuna, J. L., & Rodríguez-Leyva, I. (2024). Parkinson’s disease patients show delayed hemodynamic changes in primary motor cortex in fine motor tasks and decreased resting-state interhemispheric functional connectivity: A functional near-infrared spectroscopy study. <em>Neurophotonics</em>, <em>11</em>(2), 025004. <a href="https://doi.org/10.1117/1.NPh.11.2.025004">https://doi.org/10.1117/1.NPh.11.2.025004</a></div> <div> <div> <div>Guevara, E., Solana-Lavalle, G., & Rosas-Romero, R. (2024). Integrating fNIRS and machine learning: Shedding light on Parkinson’s disease detection. <em>EXCLI Journal</em>, <em>23</em>, 763–771. <a href="https://doi.org/10.17179/excli2024-7151">https://doi.org/10.17179/excli2024-7151</a></div> <div> <div> <div> <div> <div>Guevara, E., Kolosovas-Machuca, E. S., & Rodríguez-Leyva, I. (2024). Exploring motor cortex functional connectivity in Parkinson’s disease using fNIRS. <em>Brain Organoid and Systems Neuroscience Journal</em>, <em>2</em>, 23–30. <a href="https://doi.org/10.1016/j.bosn.2024.04.001">https://doi.org/10.1016/j.bosn.2024.04.001</a></div> </div> </div> </div> </div> </div> </div> </div>
Haxby et al. (2001): Faces and Objects in Ventral Temporal Cortex (fMRI)
<pre><a href="http://data.pymvpa.org/datasets/haxby2001/">http://data.pymvpa.org/datasets/haxby2001/</a> This is a block-design fMRI dataset from a study on face and object representation in human ventral temporal cortex. It consists of 6 subjects with 12 runs per subject. In each run, the subjects passively viewed greyscale images of eight object categories, grouped in 24s blocks separated by rest periods. Each image was shown for 500ms and was followed by a 1500ms inter-stimulus interval. Full-brain fMRI data were recorded with a volume repetition time of 2.5s, thus, a stimulus block was covered by roughly 9 volumes. This dataset has been repeatedly reanalyzed. For a complete description of the experimental design, fMRI acquisition parameters, and previously obtained results see the references_ below. Terms Of Use ============ The original authors of :ref:`Haxby et al. (2001) <HGF+01>` hold the copyright of this dataset and made it available under the terms of the `Creative Commons Attribution-Share Alike 3.0`_ license. .. _Creative Commons Attribution-Share Alike 3.0: http://creativecommons.org/licenses/by-sa/3.0/</pre> <pre>References ========== :ref:`Haxby, J., Gobbini, M., Furey, M., Ishai, A., Schouten, J., and Pietrini, P. (2001) <HGF+01>`. Distributed and overlapping representations of faces and objects in ventral temporal cortex. Science 293, 2425–2430. :ref:`Hanson, S., Matsuka, T., and Haxby, J. (2004) <HMH04>`. Combinatorial codes in ventral temporal lobe for object recognition: Haxby (2001). revisited: is there a “face” area? NeuroImage 23, 156–166. :ref:`O’Toole, A. J., Jiang, F., Abdi, H., & Haxby, J. V. (2005) <OJA+05>`. Partially distributed representations of objects and faces in ventral temporal cortex. Journal of Cognitive Neuroscience, 17, 580–590. :ref:`Hanke, M., Halchenko, Y.O., Sederberg, P.B., Olivetti, E., Fründ, I., Rieger, J.W., Herrmann, C.S., Haxby, J.V., Hanson, S. and Pollmann, S (2009) <HHS+09b>`. PyMVPA: a unifying approach to the analysis of neuroscientific data. Frontiers in Neuroinformatics, 3:3.</pre> <p> </p>
Data set for "Diverse long-range axonal projections of excitatory layer 2/3 neurons in mouse barrel cortex"
<p>Data set for: Yamashita T, Vavladeli A, Pala A, Galan K, Crochet S, Petersen SSA, Petersen CCH (2018) Diverse long-range axonal projections of excitatory layer 2/3 neurons in mouse barrel cortex. Front Neuroanat 12: 33. https://doi.org/10.3389/fnana.2018.00033</p> <p>There are 25 files in this data upload:</p> <p>1. '2018_Yamashita_FrontNeuroanat.pdf' - this a pdf version of the online publication.</p> <p>2. 'Yamashita_Figure2_Quantification.xlsx' - this is a Microsoft Excel file giving the locations of high density axonal projections from layer 2/3 pyramidal neurons in the mouse C2 barrel column in the coordinate frame of Paxinos & Franklin (2001) The mouse brain in stereotaxic coordinates. Academic Press. The data are plotted in Figure 2 of Yamashita et al., 2018.</p> <p>3. 'Yamashita_Figure7_Quantification.xlsx' - this is a Microsoft Excel file giving the dendritic length, number of dendrites, number of dendritic nodes and total axonal length, as well as the axonal length in the different projection zones for each reconstructed neuron. The data are plotted in Figure 7 of Yamashita et al., 2018.</p> <p>4. 'Yamashita_SupMov1_S2P_AP049.mov' - this is a QuickTime video file, showing the 3D structure of neuron AP049 featured in Figure 3 of Yamashita et al., 2018.</p> <p>5. 'Yamashita_SupMov2_M1P_TY308.mov' - this is a QuickTime video file, showing the 3D structure of neuron TY308 featured in Figure 5 of Yamashita et al., 2018.</p> <p>6. 'AV198.zip' - this zipped folder contains data relating to mouse AV198: a) 'AV198_stack.tif' the z-stack of whole-brain fluorescence images from expression of tdTomato in layer 2/3 neurons of the C2 barrel column of mouse AV198. b) 'AV198_ROI_Box.zip' can be loaded into FIJI (https://fiji.sc) and indicates projection regions by a box. c) 'AV198_ROI_Point.zip' can be loaded into FIJI (https://fiji.sc) and indicates projection regions by a point. d) 'AV198_Paxinos' is a folder showing the coronal fluorescent brain sections in pdf format overlaid on the equivalent drawing from Paxinos & Franklin (2001) The mouse brain in stereotaxic coordinates. Academic Press.</p> <p>7. 'AV199.zip' - same as 'AV198.zip' but for mouse AV199.</p> <p>8. 'AV201.zip' - same as 'AV198.zip' but for mouse AV201.</p> <p>9. 'AV202.zip' - same as 'AV198.zip' but for mouse AV202.</p> <p>10. 'AV203.zip' - same as 'AV198.zip' but for mouse AV203.</p> <p>11. 'AP042.ASC' - Neurolucida (http://www.mbfbioscience.com/neurolucida) data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse AP042. Brain contours are also traced.</p> <p>12. 'AP044.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse AP044. Brain contours are also traced.</p> <p>13. 'AP046.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse AP046. Brain contours are also traced.</p> <p>14. 'AP047.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse AP047. Brain contours are also traced.</p> <p>15. 'AP049.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse AP049. Brain contours are also traced.</p> <p>16. 'TY220.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY220. Brain contours are also traced.</p> <p>17. 'TY288.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY288. Brain contours are also traced.</p> <p>18. 'TY300.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY300. Brain contours are also traced.</p> <p>19. 'TY302.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY302. Brain contours are also traced.</p> <p>20. 'TY308.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY308. Brain contours are also traced.</p> <p>21. 'TY310.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY310. Brain contours are also traced.</p> <p>22. 'TY337.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY337. Brain contours are also traced.</p> <p>23. 'TY345.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY345. Brain contours are also traced.</p> <p>24. 'TY367.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY367. Brain contours are also traced.</p> <p>25. 'TY369.ASC' - Neurolucida data file of the 3D reconstruction of axon and dendrite from the single neuron labelled in mouse TY369. Brain contours are also traced.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170131_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170131_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p> <p><strong>History</strong></p> <ul> <li>Version 2 - corrects a error with the electrode mapping.</li> <li>Version 1 - initial release.</li> </ul>
Dataset: Feedback contribution to surface motion perception in the human early visual cortex
<p><strong>Dataset</strong></p> <p>Dataset accompanying the manuscript "Feedback contribution to surface motion perception in the human early visual cortex" (<a href="https://doi.org/10.1101/653626">biorxiv</a>).</p> <p><strong>Description</strong></p> <p>fMRI data are arrange by subject (following BIDS convention). For each subject, there are subfolders for anatomical and functional MRI data.</p> <p>├── sub-01<br> │ ├── anat<br> │ │ └── ...<br> │ ├── func<br> │ │ └── ...<br> │ ├── func_se<br> │ │ └── ...<br> │ └── func_se_op<br> │ └── ...</p> <p>The subfolder 'anat' contains four images from the MP2RAGE sequence (among these, T1 and proton-density weighted images). The subfolder 'func' contains the functional data (GE EPI, T2* weighted) from the main experiment (i.e. the data from which the haemodynamic response was estimated, and on which statistical analysis was performed). The subfolders 'func_se' and 'func_se_op' contain SE EPI images with opposite phase encode polarity that were used for distortion correction. Moreover, for each image/timeseries there is a json file with metadata.</p> <p>Anatomical images have been masked anteriorly (defaced). Functional images are in coronal oblique orientation, covering early visual cortex.</p> <p>The folder 'stimuli' contains information on the stimuli used for retinotopic mapping, including timecourse models used for population receptive field mapping. (These files are included here because of their relatively large file size, which would make distribution via a git repository impractical.) The software used for the presentation of retinotopic mapping stimuli (and for the corresponding analysis) is available on <a href="https://github.com/ingo-m/pyprf">github</a>.</p> <p>For example videos of the main experimental stimuli, see <a href="https://doi.org/10.5281/zenodo.2583017">zenodo.2583017</a>. If you would like to reproduce the experimental stimuli, the respective PsychoPy code can be found on <a href="https://github.com/ingo-m/PacMan/tree/master/stimuli/experiment">github</a>.</p> <p>The exact timing of events during the experiments (rest & stimulus blocks, target events) can be found in FSL-style design matrices ("3 column format") on <a href="https://github.com/ingo-m/PacMan/tree/master/analysis/FSL_MRI_Metadata">github.com/ingo-m/PacMan/tree/master/analysis/FSL_MRI_Metadata</a>.</p> <p><strong>Analysis</strong></p> <p>The analysis pipeline makes use of several MRI software packages (such as SPM and FSL for preprocessing, and CBS tools for cortical depth sampling). In order to facilitate reproducibility, the entire analysis was containerised using docker. Because of licensing issues, the docker images with the third-party software cannot be directly made available. However, the docker files and detailed instructions for the creation of the docker images are available on <a href="https://github.com/ingo-m/PacMan/tree/master/docker">github</a>.</p> <p>If you would like to reproduce the analysis, the first step will be to create the docker images (which provide an exact copy of the system environment that was used to conduct the published analysis). There are two docker images, one for the main analysis (motion correction, distortion correction, GLM fitting; named "dockerimage_pacman_jessie"), and another one for the depth sampling (named "dockerimage_cbs"). Detailed instructions on how to create the docker images can be found <a href="https://github.com/ingo-m/PacMan/blob/master/docker/Info_Prepare_PacMan_Image_Jessie.txt">here</a> and <a href="https://github.com/ingo-m/PacMan/blob/master/docker/Info_Prepare_CBS_Image.txt">here</a>.</p> <p>Once you set up the docker images, the analysis can be run automatically. For each subject, there is one parent script for the main analysis (e.g. <a href="http://github.com/ingo-m/PacMan/blob/master/analysis/20180118/metascript_01.sh">~/analysis/20180118/metascript_01.sh</a> for subject 20180118) and a separate script for the depth sampling (e.g. <a href="https://github.com/ingo-m/PacMan/blob/master/analysis/20180118/metascript_03.sh">~/analysis/20180118/metascript_03.sh</a>). The only manual adjustments you should have to perform to reproduce the analysis is to change the file paths in the first section of these scripts ('pacman_anly_path' is the parent directory containing the analysis code, i.e. the git repository, and 'pacman_data_path' is the parent directory containing the MRI data). The main analysis (metascript_01.sh) should take about 24 h per subject on a workstation with 12 cores, and the depth sampling (metascript_02.sh) about 2 h. The analysis can be run on consumer-grade hardware, but some parts of the analysis may not run with less than 16 GB of RAM (recommended: 32 GB).</p> <p>Visualisations (e.g. cortical depth profiles and signal timecourses) and group-level statistical tests are implemented in <a href="https://github.com/ingo-m/py_depthsampling/tree/PacMan">py_depthsampling</a>.</p> <p><strong>Further resources</strong></p> <p>Please refer to the research paper for more details: <a href="https://doi.org/10.1101/653626">https://doi.org/10.1101/653626</a></p> <p>The analysis pipeline can be found on <a href="https://github.com/ingo-m/PacMan">https://github.com/ingo-m/PacMan</a></p> <p>A separate repository contains the code used for visualisation of depth-sampling results: <a href="https://github.com/ingo-m/py_depthsampling/tree/PacMan">https://github.com/ingo-m/py_depthsampling/tree/PacMan</a></p> <p>Free & open source software package for population receptive field mapping: <a href="https://github.com/ingo-m/pyprf">https://github.com/ingo-m/pyprf</a></p> <p> </p>
Data set for "Distinct contributions of whisker sensory cortex and tongue-jaw motor cortex in a goal-directed sensorimotor transformation"
<p>Data set for: Mayrhofer JM, El-Boustani S, Foustoukos G, Auffret M, Tamura K, Petersen CCH (2019) Distinct contributions of whisker sensory cortex and tongue-jaw motor cortex in a goal-directed sensorimotor transformation. Neuron https://doi.org/10.1016/j.neuron.2019.07.008</p> <p>There are 2 files in this upload:</p> <p>1. The file named "2019_Mayrhofer_Neuron.pdf" is the Open Access pdf file of the manuscript published in Neuron.</p> <p>2. The file named "Mayrhofer_data_code.zip" (~20 GB) is a zipped version of a folder "Mayrhofer_data_code" (~57 GB), which contains the data analysed in the study along with the Matlab code used to generate the published figures. The analysis code is in a subfolder named "MatlabCode", and the specific code for generating each figure panel is in a sub-subfolder named "Figures_tjM1_paper". When running the code, you need to set the Matlab file path to be "Mayrhofer_data_code". In addition, you should add the folder "Mayrhofer_data_code" with subfolders in Matlab "Set Path". The figures will be saved in a subfolder named "Figures". Some parts of the code rely upon previous results, and need to be executed sequentially in the order of the figure panels in the journal publication.</p>
Data For Scalco et al. Clinicopathological correlates of quantitative Amyloid-B Pathology in the Temporal Cortex: Machine learning analysis of 131 cases from an ADRC
<p>Dataset containing 131 de-identified whole slide images (WSIs) with a respective data dictionary. </p> <p><strong>Paper</strong>: Scalco, R., Oliveira, L.C., Lai, Z. et al. Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases. acta neuropathol commun 12, 134 (2024). https://doi.org/10.1186/s40478-024-01827-7</p> <p><strong>Details</strong>: A total of 131 .svs. WSIs, de-identified using svs-deidentifier v 0.9.1-beta (https://github.com/pearcetm/svs-deidentifier/releases). Dataset is uploaded in batches due to Zenodo data upload limitations.</p> <p><strong>Slide curation/preparation</strong>: All samples were retrieved from archives of the University of California, Davis Alzheimer’s Disease Center Brain Bank (<a href="https://www.ucdmc.ucdavis.edu/alzheimers/">https://www.ucdmc.ucdavis.edu/alzheimers/</a>). Archival samples analyzed in this study were 5 μm formalin fixed, paraffin embedded sections of the superior and middle temporal gyrus from human brain. The tissue had been previously stained with an amyloid-β antibody (4G8, recognizing residues 17-24, BioLegend, formerly Covance) that were first pretreated with formic acid to rid samples of endogenous protein. All slides were digitized using an Aperio AT2 between 20x and 40x magnification.</p> <p><strong>Code:</strong> Please refer to <a href="https://github.com/ucdrubinet/BrainSec">https://github.com/ucdrubinet/BrainSec</a> and <a href="https://github.com/keiserlab/plaquebox-paper">https://github.com/keiserlab/plaquebox-paper</a></p>
MERFISH data of the developing mouse visual cortex under normal- and dark-rearing
<p>MERFISH data for the manuscript "Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex"</p>
Dataset: Insular cortex dopamine 1 and 2 receptors in methamphetamine conditioned place preference and aversion: Age and sex differences
<p>Dataset for Insular cortex dopamine 1 and 2 receptors in methamphetamine conditioned place preference and aversion: Age and sex differences</p>
Deposited data for 'Structural and functional map for forelimb movement phases between cortex and medulla'; Yang, Kanodia and Arber; 2023
<p>Primary source data for figures in '<strong>Structural and functional map for forelimb movement phases between cortex and medulla</strong>'; <a href="https://doi.org/10.1016/j.cell.2022.12.009">Yang et al. 2023</a> </p> <p> </p> <p> </p>
Calcium time series of cortex in a rat model of cortical dysplasia
<p>In vitro Calcium time series of rat (P30) primary motor cortex, were recorder by a CCD camera coupled to stereo-fluoerscence<br> microscope, with a fs = 300ms, following the next sequence: <strong>Basal, <em>Stimulus</em>, Rest.</strong></p> <p>All data is included in a compressed file named <strong>calcium_timeseries.tar.gz.</strong></p> <p>There are two groups of rats: <strong>Control</strong> (control animals), and <strong>BCNU</strong> (experimental animals using the BCNU/carmustine model of cortical dysplasia [1]).</p> <p>Time series are stored in .<strong>csv</strong> files with file names as <strong>R?Pilo-KCl.csv</strong> (where <strong>?</strong> indicates the rat ID). Each of these files holds the two recordings, one for each <em>Stimulus</em>, the first being <em>pilocarpine</em>, followd by <em>KCl</em> used as a control of cellular activity. (pilocarpine, KCl). recording session: The first 150 seconds of these time series correspond to basal activity, followed by 30 s of pilocarpine stimulus, and the rest of spontaneous activity after stimulation, for a total of 15 minutes for each <em>Stimulus</em>. The number of cells recorded varied between animals, as indicated by the number of columns in these .csv files. All of these files have the same number of rows (6000), with each row indicating a frame in the time series. The file <strong>dataEx.png</strong> illustrates this organization.</p> <p>Files named <strong>R?-Coor.csv</strong> (<strong>?</strong> indicates rat ID) show the <em>x</em> and <em>y</em> coordinates of every recorded cell, one for each row, ordered as<br> they appear in the calcium activity recordings. </p> <p><br> Authors:</p> <ul> <li>Ana Aquiles anaaquiles@ciencias.unam.mx</li> <li>Tatiana Fiordelisio tfiorde@ciencias.unam.mx</li> <li>Hiram Luna-Munguía hiram_luna@inb.unam.mx</li> <li>Luis Concha lconcha@unam.mx</li> </ul> <p> </p> <p>1. Benardete, E. A., & Kriegstein, A. R. (2002). Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex. <em>Epilepsia</em>, <em>43</em>(9), 970-982.</p>
Structural and Molecular Analysis of Adult Mouse Astrocytes and Vascular Connectivity in the Cortex and Hippocampus
<p>After image acquisition (0-RAW_CL230331_E2_serie1) and deconvolution (1-Deconvolved_CL230331_E2_serie1) using confocal microscopy and the SVI Huygens software,respectively, the image processing was conducted using Imaris, Fiji, and Matlab software. This process involved a sequence of manual operations (2-Imaris_surfaces_CL230331_E2_serie1) and custom Groovy scripts (5-Groovy scripts).</p> <p>The dataset analysis (3-Imaris_final_CL230331_E2_serie1_ims) allowed for a deeper investigation of morphological and molecular properties of adult mouse astrocytes (4-Image analysis_CL230331_E2_serie1) in two brain regions, the Isocortex and the Hippocampus, known to be interconnected to support multiple cognitive functions.</p>
Data set for "Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex"
<p>Data set for: Sermet BS, Truschow P, Feyerabend M, Mayrhofer JM, Oram TB, Yizhar O, Staiger JF, Petersen CCH (2019) Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex. eLife 8: e52665. https://doi.org/10.7554/eLife.52665</p> <p>There are 2 files in this upload:</p> <p>1. The file named "2019_Sermet_eLife.pdf" is the Open Access pdf file of the manuscript published in eLife.</p> <p>2. The file named "Sermet_data_code.zip" (~5 GB) is a zipped version of a folder "Sermet_data_code" (~5 GB), which contains the data analysed in the study along with the Matlab code used to generate the published figures. When unzipped, the folder contains 8 Matlab '.m' files with analysis code and one '.mat' data file. In order to run the analysis of the data set, you need to execute 'PopPlot.m'.</p>
Full summary statistics of mixQTL for GTEx v8 Kidney Cortex
<p>The mixQTL method is described in paper doi.org/10.1101/2020.04.22.050666. Please cite the original paper if using the data.</p>
Full summary statistics of mixQTL for GTEx v8 Kidney_Cortex
The mixQTL method is described in paper doi.org/10.1101/2020.04.22.050666. Please cite the original paper if using the data.
Full summary statistics of mixQTL for GTEx v8 Brain_Frontal_Cortex_BA9
The mixQTL method is described in paper doi.org/10.1101/2020.04.22.050666. Please cite the original paper if using the data.
nNOS-expressing interneurons control basal and behaviorally evoked arterial dilation in somatosensory cortex of mice
<p>Cortical neural activity is coupled to local arterial diameter and blood flow. However, which neurons control the dynamics of cerebral arteries is not well understood. We dissected the cellular mechanisms controlling the basal diameter and evoked dilation in cortical arteries in awake, head-fixed mice. Locomotion drove robust arterial dilation, increases in gamma band power in the local field potential (LFP), and increases calcium signals in pyramidal and neuronal nitric oxide synthase (nNOS)-expressing neurons. Chemogenetic or pharmocological modulation of overall neural activity up or down caused corresponding increases or decreases in basal arterial diameter. Modulation of pyramidal neuron activity alone had little effect on basal or evoked arterial dilation, despite pronounced changes in the LFP. Modulation of the activity of nNOS-expressing neurons drove changes in the basal and evoked arterial diameter without corresponding changes in population neural activity.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.