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157
datasets available to search
ShareScore release 0.9.0
Dataset results
157 results for “Dot1l”
RNA-sequencing of Dot1L-deficient B cell subsets
GEO Series GSE138401. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Novel Inhibitors of the Histone-Methyltransferase DOT1L Show Potent Antileukemic Activity in Patient-derived Xenografts (RNA-seq dataset)
GEO Series GSE149184. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Dot1L recruits OGT target chromatin to regulate histones O-GlcNAcylation
GEO Series GSE200059. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DOT1L controls NK cell maturation and lineage integrity [RNA-seq D0 & D2]
GEO Series GSE222233. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Dot1L regulates the rate of lung alveolar regeneration through control of oxidative phosphorylatio
GEO Series GSE210800. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
RNA expression in WT and Dot1L KO CD8 T cell subsets
GEO Series GSE138910. Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing.
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia.
GEO Series GSE83671. Homo sapiens. 59 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Genome-wide maps of H3K79Me3 binding sites in ovarian cancer cell line OVCAR5 and expression profile of DOT1L knockdown OVCAR5 cells
GEO Series GSE199474. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide maps of H3K79Me3 binding sites in ovarian cancer cell line OVCAR5 and expression profile of DOT1L knockdown OVCAR5 cells (RNA-seq)
GEO Series GSE199472. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq]
GEO Series GSE76748. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged Acute Lymphoblastic Leukemia’ [RNA-seq]
GEO Series GSE230791. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
DOT-1.1 (DOT1L) deficiency in C. elegans leads to small RNA-dependent gene activation [small RNA, embryos]
GEO Series GSE223703. Caenorhabditis elegans. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged Acute Lymphoblastic Leukemia’ [ATAC-seq]
GEO Series GSE230799. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition. [SLAM-Seq]
GEO Series GSE173571. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
DOT1L-mediated H3K79me2 directs B-cell repertoire establishment, marginal zone development and germinal center function
GEO Series GSE306634. Mus musculus. 21 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Transcriptional alterations in the brain following Dot1l conditional knockout using the Emx1-Cre mouse line at embryonic day 16.5 [EmxDotRNAE16]
GEO Series GSE291845. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
DOT1L inhibition exerts anti-tumor effects through activating interferon signaling in breast cancer cells
GEO Series GSE286942. Homo sapiens. 15 samples. Type: Expression profiling by array.
single-nucleus transcriptomic analysis of cortical tissue from control and Dot1l HET 10 week old mice.
GEO Series GSE279120. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Common and distinct functions of mouse Dot1l in the regulation of endothelial transcriptome
GEO Series GSE214945. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Functional interdependency of BRD4 and DOT1L in MLL leukaemia
GEO Series GSE71780. Homo sapiens. 33 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.