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3,465 results for “Embryo”
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism- embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Danio rerio (Cyprinidae) - whole organism - embryo
Image of Danio rerio (Cyprinidae) - whole organism - embryo
Transcriptomic profiling of clobetasol propionate-induced immunosuppression in challenged zebrafish embryos
<p>We have conducted an immune challenge experiment on 48h zebrafish embryos, which were previously treated with the immunosuppressive drug clobetasol propionate (CP). The embryos' immune system was challenged by injection of a mix of different pathogen associated molecular patterns (PAMPs). RNA sequencing was performed in order to detect altered molcular expression levels induced by CP, PAMPs and a combination of both. The data was published in <a href="https://doi.org/10.1016/j.ecoenv.2022.113346" target="_blank" rel="noopener">Essfeld <em>et al.</em> 2022</a>.</p> <p>The uploaded data archive (<a href="https://www.7-zip.org/">7-zip</a> compressed) consists of three major data types:<br>1. MultiQC reports from raw RNA-Seq read processing and QC (50bp SR)<br>2. Result tables from differential gene expression analysis (DGEA) with DESEq2<br>3. Result tables from Overrespresentation Analysis (ORA) with clusterProfiler</p> <p>Gene count normalization and DGEA was conducted with DESeq2 (<a href="https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0550-8">Love et al., 2014</a>, DOI 10.1186/s13059-014-0550-8) . Three biological replicates per condition, exposure treatments were compared with respect to the control group in a pairwise fashion, applying Wald’s t-test. P values were corrected for multiple testing with independent hypothesis weighting (IHW) (<a href="https://www.nature.com/articles/nmeth.3885">Ignatiadis et al., 2016</a>, DOI 10.1038/nmeth.3885 ) after Benjamini-Hochberg (BH). To improve the signal to statistical noise ratio, the obtained log<sub>2</sub>-fold change (lfc) values were shrunk with the apeglm method described by Zhu and colleagues (<a href="https://academic.oup.com/bioinformatics/article/35/12/2084/5159452?login=true">2019</a>, DOI 10.1093/bioinformatics/bty895 ) before DGEA result tables were subjected to ORA via clusterProfiler (<a href="https://www.liebertpub.com/doi/10.1089/omi.2011.0118">Yu et al., 2012</a>, DOI 10.1089/omi.2011.0118).</p> <p>The ArrayExpress accession number E-MTAB-11092, provides access to the raw and DESeq2 normalized gene count matrices upon which these analysis were performed. Genes were annotated through the biomaRt package (<a href="https://www.nature.com/articles/nprot.2009.97.pdf?origin=ppub">Durinck et al., 2009</a>, DOI 10.1038/nprot.2009.97 ) in R (<a href="https://www.r-project.org/">R Core Team 2021</a>).</p>
Fig. 1. N in Obtaining Oviparous Grass Snake, Natrix Natrix (Serpentes, Colubridae), Embryos At Early Developmental Stages By Caesarean Section
Fig. 1. N. natrix embryos at developmental stages A. 20. B. 22. C. 24. D. 25. E. 26. F. 27: av —auditory vesicle; cl —crystalline
Fig. 3 in An Investigation Of Embryo And Eggshell Development In Trichuris Suis (Nematoda, Trichuridae0 Under Laboratory Conditions
Fig. 3. Eggs of Trichuris suis at bean-like embryo stage of development: а — sampled from nematode gonads, 25th day of cultivation (×400); b — sampled from faeces of infected pigs, 20th day of cultivation (×450).
Fig. 5 in An Investigation Of Embryo And Eggshell Development In Trichuris Suis (Nematoda, Trichuridae0 Under Laboratory Conditions
Fig. 5. Infectious Trichuris suis egg: а — sampled from nematode gonads, 40th day of cultivation (×350); b — sampled from faeces of infected pigs, 30th day of cultivation (×450).
Fig. 1 in An Investigation Of Embryo And Eggshell Development In Trichuris Suis (Nematoda, Trichuridae0 Under Laboratory Conditions
Fig. 1. Eggs of Trichuris suis at the protoplast stage of development: a — sampled from nematode gonads: 1 — unformed, 2 — formed (×350); b — sampled from faeces of sick pigs (×450).
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.