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102 results for “GBs”
Data from: Genetic sex assignment in wild populations using GBS data: a statistical threshold approach
Establishing the sex of individuals in wild systems can be challenging and often requires genetic testing. Genotyping-by-sequencing (GBS) and other reduced representation DNA sequencing (RRS) protocols (e.g., RADseq, ddRAD) have enabled the analysis of genetic data on an unprecedented scale. Here, we present a novel approach for the discovery and statistical validation of sex-specific loci in GBS datasets. We used GBS to genotype 166 New Zealand fur seals (NZFS, Arctocephalus forsteri) of known sex. We retained monomorphic loci as potential sex-specific markers in the locus discovery phase. We then used (i) a sex-specific locus threshold (SSLT) to identify significantly male-specific loci within our dataset and (ii) a significant sex-assignment threshold (SSAT) to confidently assign sex in silico the presence or absence of significantly male-specific loci to individuals in our dataset treated as unknowns (98.9% accuracy for females; 95.8% for males, estimated via cross-validation). Furthermore, we assigned sex to 86 individuals of true unknown sex using our SSAT, and assessed the effect of SSLT adjustments on these assignments. From 90 verified sex-specific loci, we developed a panel of three sex-specific PCR primers that we used to ascertain sex independently of our GBS data, which we show amplify reliably in at least three other pinniped species. Using monomorphic loci normally discarded from large SNP datasets is an effective way to identify robust sex-linked markers for non-model species. Our novel pipeline can be used to identify and statistically validate monomorphic and polymorphic sex-specific markers across a range of species and RRS datasets.
Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) Patients
ClinicalTrials.gov study NCT02780570. IPD Sharing: NO. Countries: 1. Publications: 3.
Impact of GBS on CVD in Type 2 Diabetes Mellitus
ClinicalTrials.gov study NCT00787670. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Neonatal Sepsis and GBS Carriage Study
ClinicalTrials.gov study NCT00861055. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Probiotic on Prevention of GBS Vaginal Infection During Pregnancy
ClinicalTrials.gov study NCT03688321. IPD Sharing: YES. Countries: 1. Publications: 1.
Feasibility Study for Identifying Anti Capsular Antibody Protection Against Invasive Group B Streptococcus (GBS) Disease in Newborns of 0-6 Days Age (Early Onset Disease [EOD]) as Well as Among Infant
ClinicalTrials.gov study NCT01888471. IPD Sharing: NO. Countries: 1. Publications: 1.
Intrapartum Rapid GBS Testing in Patients Presenting With Threatened Preterm Labor
ClinicalTrials.gov study NCT02511444. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization
ClinicalTrials.gov study NCT01505361. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Intrapartum Effect of Vancomycin on Rectovaginal GBS Colonization
ClinicalTrials.gov study NCT02814318. IPD Sharing: NO. Countries: 1. Publications: 6.
Burden of Invasive Group B Streptococcal (GBS) Disease in Young Infants in China
ClinicalTrials.gov study NCT01933646. IPD Sharing: Not stated. Countries: 1. Publications: 1.
JET-GBS - Japanese Eculizumab Trial for GBS
ClinicalTrials.gov study NCT02493725. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Preparing for Maternal GBS Vaccine Trials in Africa
ClinicalTrials.gov study NCT06833957. IPD Sharing: YES. Countries: 4. Publications: 17.
Effect of Probiotics on GBS Colonization Status During Pregnancy: A Pilot Randomized Controlled Trial
ClinicalTrials.gov study NCT02528981. IPD Sharing: Not stated. Countries: 1. Publications: 12.
GBS Sero-correlate of Protection
ClinicalTrials.gov study NCT02215226. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Our Study Aims to Determine if Nerve Alterations in Acute GBS and CIDP Detectable by Ultrasound Match Electrodiagnostic Findings and if This Method Aids Early Diagnosis, Predict Their Outcomes and Dif
ClinicalTrials.gov study NCT06615622. IPD Sharing: UNDECIDED. Countries: 1. Publications: 8.
Developing a Controlled Human Infection Model for Group B Streptococcus (CHIM_GBS)
ClinicalTrials.gov study NCT04059510. IPD Sharing: NO. Countries: 1. Publications: 7.
Interest of the Detection of Hyper-virulent Clone ST17 of Group B Strep (GBS) for the Prevention of Neonatal GBS Meningitis
ClinicalTrials.gov study NCT01719510. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Intravenous Immunoglobulin (IVIG) Versus Plasma Exchange (PE) for Ventilated Children With Guillain Barre Syndrome (GBS)
ClinicalTrials.gov study NCT01306578. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Detection of individual ploidy levels with genotyping-by-sequencing (GBS) analysis
Open the record for dataset details and reuse information.
Data from: Comparing pool‐seq, rapture, and GBS genotyping for inferring weak population structure: the American lobster (Homarus americanus) as a case study
Open the record for dataset details and reuse information.
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International Brain Laboratory public data
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OpenNeuro
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