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129
datasets available to search
ShareScore release 0.9.0
Dataset results
129 results for “Gain-of-Function”
Gain-of-function MUC5B Promoter Variant, Strongly Linked to Idiopathic Pulmonary Fibrosis, Defines an Epigenetically Poised Enhancer
GEO Series GSE157691. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
GEO Series GSE68249. Homo sapiens. 30 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing.
The transcriptome of hand2 loss- and gain-of-function embryonic cardiomyocytes
GEO Series GSE241049. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
Human Germline Heterozygous Gain-of-Function STAT6 Variants Cause Severe Allergic Disease
GEO Series GSE215406. Homo sapiens; Homo. 16 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide gain-of-function screening characterized lncRNAs as tumor immune response regulators
GEO Series GSE202093. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
GEO Series GSE65458. Homo sapiens. 24 samples. Type: Expression profiling by array.
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
GEO Series GSE68248. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker (NG_Capture-C)
GEO Series GSE159874. Homo sapiens. 36 samples. Type: Other.
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice [bulk RNA-seq]
GEO Series GSE207934. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Gain-of-Function p53 Protein Transferred via Small Extracellular Vesicles Promotes Conversion of Fibroblasts to a Cancer-Associated Phenotype
GEO Series GSE148698. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Only the loss-of-function but not the gain-of-function properties of mutant TP53 are critical for the sustained proliferation, survival and metastasis of a broad range of cancer cells [colon cancer]
GEO Series GSE181011. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Sex and mutation specific p53 gain-of-function activity in gliomagenesis [RNA-seq]
GEO Series GSE188709. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Gain-of-function genetic perturbationssimultaneouslyacross500 barcoded cancer cell lines
GEO Series GSE238126. Homo sapiens. 66 samples. Type: Other.
Endothelial Cell Expression of a STING Gain-of-function Mutation Initiates Pulmonary Lymphocytic Infiltration
GEO Series GSE260893. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.
Impaired Cell Fate by Gain-of-function Mutations in a Chromatin Reader
GEO Series GSE125186. Homo sapiens. 43 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice [single cell RNA-seq]
GEO Series GSE207935. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
A Gain-of-Function Genomic Screen Identifies the Orphan Nuclear Receptor TLX as an Enhancer of STAT1-mediated Transcription and Immunity to Toxoplasma gondii: TLX siRNA
GEO Series GSE55750. Homo sapiens. 8 samples. Type: Expression profiling by array.
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling
GEO Series GSE264373. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
A Stat1 gain-of-function mutant disrupts normal Stat4 innate lymphocyte programs during viral infection [scMulti-omics-seq]
GEO Series GSE284323. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice (Bulk RNA-Seq)
GEO Series GSE201731. Mus musculus. 95 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.