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ShareScore release 0.9.0
Dataset results
568 results for “Glucose Metabolism”
Efficacy of Pioglitazone on Bone Metabolism in Postmenopausal Women With Impaired Fasting Glucose.
ClinicalTrials.gov study NCT00708175. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Effects of Co-admin of Colesevelam and Sitagliptin on Glucose Metabolism in Subjects With Type 2 Diabetes Mellitus
ClinicalTrials.gov study NCT01092663. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Data from: Deuterium metabolic imaging phenotypes mouse glioblastoma heterogeneity through glucose turnover kinetics
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Sirtuin3 ensures the metabolic plasticity of neurotransmission during glucose deprivation
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Chronic hyperadiponectinemia induced by transgenic overexpression increases plasma exosomes without significantly improving glucose and lipid metabolism
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Restoring hippocampal glucose metabolism rescues cognition across Alzheimer disease pathologies
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The effect of dietary supplementation with blueberry, cyanidin-3-O-β-glucoside, yoghurt and its peptides on gene expression associated with glucose metabolism in skeletal muscle obtained from a high-fat-high-carbohydrate diet induced obesity model
<p><span>Obesity is a leading global health problem contributing to various chronic diseases, including type II diabetes mellitus</span> <span>(T2DM). The aim of this study was to investigate whether blueberries, yoghurt, and their respective bioactive components, Cyanidin-3-O-β-glucoside (C3G) and peptides alone or in combinations, alter the expression of genes related to glucose metabolism in skeletal muscles from diet-induced obese mice. In extensor digitorum longus (EDL), yoghurt up-regulated the expression of activation of 5'adenosine monophosphate-activated protein kinase (AMPK), insulin receptor substrate-1 (IRS-1), phosphatidylinositol-3 kinase (PI3K) and glucose transporter 4 (GLUT4), and down-regulated the expression of angiotensin II receptor type 1 (AGTR-1). The combination of blueberries and yoghurt down-regulated the mRNA expression of AGTR-1 and Forkhead box protein O1 (FoxO1) in the EDL. Whereas the combination of C3G and peptides down-regulated AGTR-1 and up-regulated GLUT4 mRNA expression in the EDL. In the soleus, blueberries and yoghurt alone, and their combination down-regulated AGTR-1 and up-regulated GLUT4 mRNA expression. In summary blueberries and yoghurt, regulated multiple genes associated with glucose metabolism in skeletal muscles, and therefore may play a role in the management and prevention of T2DM.</span></p>
Dataset of "Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats"
<p>We fed ExHC rats and Congenic (ExHC.BN-<em>Dihc2<sup>BN</sup></em>) rats on two diets (0%- or 2%-cholesterol semi-purified AIN76-based diet) for 2 weeks. We measured the parameters related to homocysteine and lipid metabolism in the obtained samples. This data set includes raw data of hepatic microarray analysis with ExHC and Congenic rats. Additionally, we measured Smek2 and Sardh mRNA in rat hepatic cell line (MCA-RH7777) under Smek2 knock-down condition.</p>
Data for: Link between glucose metabolism and EMT drives triple negative breast cancer migratory heterogeneity
<p>Intracellular and environmental cues result in heterogeneous cancer cell populations with different metabolic and migratory behaviors. While glucose metabolism and EMT have previously been linked, we aim to understand how this relationship fuels cancer cell migration. We show that while glycolysis drives single-cell migration in confining microtracks, fast and slow cells display different migratory sensitivities to glycolysis and oxidative phosphorylation inhibition. Phenotypic sorting of highly and weakly migratory subpopulations (MDA<sup>+</sup>, MDA<sup>-</sup>) reveals that more mesenchymal, highly migratory MDA<sup>+</sup> preferentially use glycolysis while more epithelial, weakly migratory MDA<sup>-</sup> utilize mitochondrial respiration. These phenotypes are plastic and MDA<sup>+</sup> can be made less glycolytic, mesenchymal, and migratory and MDA<sup>-</sup> can be made more glycolytic, mesenchymal, and migratory via modulation of glucose metabolism or EMT. These findings reveal an intrinsic link between EMT and glucose metabolism that controls migration. Identifying mechanisms fueling phenotypic heterogeneity is essential to develop targeted metastatic therapeutics.</p>
Growth Hormone and Glucose Metabolism
ClinicalTrials.gov study NCT00929799. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism
ClinicalTrials.gov study NCT02041104. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Short-term Effects of Tai Chi Chuan Exercise on the Regulation of Lipid and Glucose Metabolisms and Endothelial Function
ClinicalTrials.gov study NCT03503084. IPD Sharing: NO. Countries: 1. Publications: 7.
Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health
ClinicalTrials.gov study NCT02509988. IPD Sharing: Not stated. Countries: 3. Publications: 10.
Training in the Fasted State, Glucose Metabolism and Energy Balance
ClinicalTrials.gov study NCT02744183. IPD Sharing: NO. Countries: 1. Publications: 3.
Investigating the Postprandial Glucose Metabolism After Treatment With Faster-acting Insulin Aspart in Subjects With Type 1 Diabetes
ClinicalTrials.gov study NCT02568280. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Glucose Metabolism Effects of Vitamin D Supplementation in Prediabetes
ClinicalTrials.gov study NCT01479933. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effects of Spasticity on Glucose Metabolism in Individuals With Spinal Cord Injury
ClinicalTrials.gov study NCT03859960. IPD Sharing: NO. Countries: 0. Publications: 6.
Effects and Mechanisms of n-3 PUFAs and Irisin on Abnormal Glucose Metabolism After GDM.
ClinicalTrials.gov study NCT03023293. IPD Sharing: UNDECIDED. Countries: 1. Publications: 7.
Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD
ClinicalTrials.gov study NCT06389851. IPD Sharing: NO. Countries: 1. Publications: 4.
The Effects of Light on Glucose Metabolism
ClinicalTrials.gov study NCT03829982. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.