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datasets available to search
ShareScore release 0.9.0
Dataset results
37 results for “HLA class I”
Systems biology demonstrates the predominant role of circulating interferon-alpha in primary Sjögren's syndrome and a genetic association with the class II HLA DQ locus
GEO Series GSE140161. Homo sapiens. 351 samples. Type: Expression profiling by array.
Gene expression analysis of immune privileged site-associated DLBCL: The effect of HLA class II downregulation
GEO Series GSE4157. Homo sapiens. 36 samples. Type: Expression profiling by array.
A large peptidome dataset improves HLA class I epitope prediction across most of the human population
GEO Series GSE131267. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Genetic disruption of class I HLA in cutaneous T-cell lymphoma
GEO Series GSE263881. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
Gene expression analysis of molecules with known function in HLA class II antigen processing and presentation in hematopoietic and (cytokine pre-treated) non-hematopoietic cells.
GEO Series GSE38798. Homo sapiens. 28 samples. Type: Expression profiling by array.
Case Report: Persistent hypogammaglobulinemia and mixed chimerism after HLA class-II disparate-hematopoietic stem cell transplant
GEO Series GSE263200. Homo sapiens. 18 samples. Type: Other.
Genome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape
GEO Series GSE27544. Homo sapiens. 22 samples. Type: Expression profiling by array.
Extracellular Vesicles from Cytokine-Treated Human Pancreatic Ductal Cells Enhance HLA Class I Expression in Beta Cells
GEO Series GSE316823. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Targeting KRASG12V mutations with HLA class II restricted TCR for the immunotherapy in solid tumors
GEO Series GSE232897. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing; Other.
Gene and protein sequence features augment HLA class I ligand predictions (ribosome profiling)
GEO Series GSE210998. Homo sapiens. 6 samples. Type: Other.
Gene and protein sequence features augment HLA class I ligand predictions (mRNA sequencing)
GEO Series GSE210999. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Pretransplant active disease status and HLA class II mismatching are associated with increased incidence and severity of cytokine release syndrome after haploidentical transplantation with posttransplant cyclophosphamide."
<p>Cytokine release syndrome (CRS) represents a life-threatening side effect after haploidentical stem cell transplantation (Haplo-SCT) with posttransplant cyclophosphamide (PT-Cy). Factors predictive of CRS development is still a matter of debate. We retrospectively analyzed 102 consecutive patients receiving a bone marrow (BM) (n = 42) or peripheral blood stem cells (PBSC) (n = 60) Haplo-SCT with PT-Cy. The two cohorts were similar in main patients' characteristics besides disease type (P = .02). Cumulative incidence of grades 1, 2, and ≥3 CRS was 80%, 52%, and 15% at a median of 2, 4, and 7 days, respectively. Moderate/High-grade fever (39°-41°), grade 1 and grade ≥3 CRS occurred more frequently after PBSC relative to BM grafts (68% vs 33%, P = .0005; 87% vs 71%, P = .009; 20% vs 7%, P = .07). Only patients experiencing grade ≥3 CRS had a worse outcome in terms of 1-year overall survival (OS) and nonrelapse mortality (NRM): 39% vs 80% (P = .002) and 40% vs 8% (P = .005), respectively. By univariate analysis the only factors associated with the increased risk of ≥3 CRS were pretransplant disease status (8% for complete remission, 11% for partial remission, and 38% for active disease, P = .002), HLA-DRB1 mismatching (57% vs 14%, P = .007), and PBSC graft (P = .07). By multivariable analysis, only pretransplant disease status (hazard ratio, HR: 6.84, P = .005) and HLA-DRB1 mismatching (HR: 17.19, P = .003) remained independent predictors of grade ≥3 CRS. Only grade ≥3 CRS is clinically relevant for the final outcome of patients receiving Haplo-SCT with PT-Cy, is more frequent after a PBSC graft and is associated with pretransplant active disease and HLA-DRB1 mismatching.</p>
Gene and protein sequence features augment HLA class I ligand predictions.
GEO Series GSE211000. Homo sapiens. 12 samples. Type: Other; Expression profiling by high throughput sequencing.
Expression date from endothelial cells stimulated with anti-HLA class I and anti-A antibody
GEO Series GSE120545. Homo sapiens. 4 samples. Type: Expression profiling by array.
Identification of Vaccinia Virus HLA Class I Peptides Presented by the Immune System
GEO Series GSE10549. Homo sapiens; Orthopoxvirus vaccinia; Bos taurus. 3 samples. Type: Protein profiling by Mass Spec.
Human CD4 cytotoxic T lymphocytes mediate potent tumor control via tumor cell HLA 2 class II expression in a humanized immune system mouse model
GEO Series GSE223026. Homo sapiens; Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I"
<p>This record contains raw data (metabolomic and RNASeq data) related to the article: "Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I"</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.