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34
datasets available to search
ShareScore release 0.9.0
Dataset results
34 results for “Hippocampi”
Amygdalae and hippocampi of C57BL/6J and A/J mouse inbred strains
GEO Series GSE17955. Mus musculus. 35 samples. Type: Expression profiling by array.
Genome-wide RNAseq from multi time point (every 4 hours) rat hippocampi with vehicle and methylprednisolone (MPL) treatment
GEO Series GSE223761. Rattus norvegicus. 48 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide RNAseq of hippocampi from single time point (2 hours post 0.75 mg/mL corticosterone injection) in adrenalectomized rats
GEO Series GSE224038. Rattus norvegicus. 8 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiles in the hippocampi and prefrontal cortex of Df16(A)+/- mice at embryonic day 17, postnatal day 6, and adult stages
GEO Series GSE29767. Mus musculus. 127 samples. Type: Expression profiling by array.
Temporal analysis of P15 and P30 hippocampi in kainate-induced seizures
GEO Series GSE4236. Rattus norvegicus. 60 samples. Type: Expression profiling by array.
Expression data from WT and Neu1 deficient 1 mo and 5 mo hippocampi
GEO Series GSE284427. Mus musculus. 12 samples. Type: Expression profiling by array.
JNK3 null vs. wild type hippocampi
GEO Series GSE22267. Mus musculus. 2 samples. Type: Expression profiling by array.
Altered gene expression in the neocortices and hippocampi of the adult S1P2-deficient and S1P3-deficient mice
GEO Series GSE7191. Mus musculus. 50 samples. Type: Expression profiling by array.
Basal and kainate-induced gene expression in A-CREB mouse hippocampi
GEO Series GSE14320. Mus musculus. 10 samples. Type: Expression profiling by array.
Bulk RNA sequencing and spatially resolved transcriptional profiling of hippocampi from mice flown on the RRRM-2 mission
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due to age, twenty 12 week-old and twenty 29 week-old mice were flown, respectively. To directly assess spaceflight effects, half of the young and old mice (10 old, 10 young) were sacrificed on-orbit after 55-58 days (ISS Terminal, ISS-T), while the other half (10 old, 10 young) were returned live to Earth after 32 days and allowed to recover for 24 days (Live Animal Return, LAR) before sacrifice. ISS-T and LAR mice were the same age at sacrifice. Both the ISS-T and LAR animals had independent ground controls (10 mice per group housed in flight hardware in matched environmental conditions), basal controls (10 mice per group sacrificed 2 days before launch), and vivarium controls (10 mice per group housed within standard vivarium habitats). Thus RRRM-2 included a total of 160 mice. This study includes bulk RNA sequencing and spatially resolved transcriptional profiling data from hippocampi from 5 old ISS-T flight animals, 3 old ISS-T ground control (GC) animals, 4 (bulk RNAseq) or 5 (spatial transcriptomics) young ISS-T flight animals, 3 young ISS-T GC animals, 3 old LAR flight animals, 3 old LAR GC animals, 3 young LAR flight animals, and 3 young LAR GC animals. Hippocampi from the right hemisphere were either processed for bulk RNA sequencing or embedded and cryosectioned. Cryosections were placed on gene expression arrays, stained and imaged. Imaging was followed by tissue permeabilization to release mRNA molecules from cells for capture onto the array surface. Subsequently, spatial transcriptomics libraries were prepared and sequenced.
Bulk RNA sequencing and spatially resolved transcriptional profiling of hippocampi from mice flown on the RR-10 mission
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end, ten (10) 14-15 weeks-old female B6129SF2/J Wild Type (WT), and ten (10) 14-15 weeks-old female B6;129S2-Cdkn1atm1Tyj/J (p21-null) mice received a pre-flight subcutaneous injection of the bone marker (Alizarin Red), and were then delivered to the ISS aboard SpaceX-21. At 7 days before euthanasia, all 20 mice received an intraperitoneal (IP) injection with a bone formation marker (Calcein). At 48 +/- 2 hours before euthanasia, all 20 mice received an IP injection with a second dose of Calcein as well as a cell proliferation marker (BrdU). Then, following 28-29 days in microgravity, the Flight mice were euthanized. Following removal of hindlimbs, carcasses were wrapped in aluminum foil, preserved in the CryoChiller, and stored at -80 C or colder until return to Earth. In addition to the Flight group, three ground control groups were also part of the study: Basal (representing the pre-launch state), Vivarium (standard vivarium housing for the same duration of time as flight), and Ground (flight habitat in the International Space Station Environment Simulator, ISSES). Twenty mice (10 of each strain) were included in each of these control groups (except Vivarium which included 12 of each strain). These were treated, euthanized and processed on the same schedule and in the same manner as the flight samples. This study includes bulk RNA sequencing and spatially resolved transcriptional profiling data from hippocampi from 5 WT flight animals and 5 WT ground control animals. Hippocampi from the right hemisphere were embedded and cryosectioned. Cryosections were either processed for bulk RNA sequencing or placed on gene expression arrays, stained and imaged. Imaging was followed by tissue permeabilization to release mRNA molecules from cells for capture onto the array surface. Subsequently, spatial transcriptomics libraries were prepared and sequenced.
5-methylcytosine modifition of mRNA from hippocampi in young and aged mice
GEO Series GSE214222. Mus musculus. 12 samples. Type: Methylation profiling by high throughput sequencing.
single cell RNA Sequencing of hippocampi of mice subjected or not to the learned helplessness paradigm
GEO Series GSE165507. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional characterization of hippocampi from novel preclinical model of drug-resistant epilepsy
GEO Series GSE157797. Mus musculus. 30 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.