Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
126
datasets available to search
ShareScore release 0.9.0
Dataset results
126 results for “ISIS”
Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease
ClinicalTrials.gov study NCT00706849. IPD Sharing: Not stated. Countries: 2. Publications: 3.
A Study to Assess the Clinical Efficacy of Donidalorsen (Also Known as IONIS-PKK-LRx and ISIS 721744) in Participants With Hereditary Angioedema
ClinicalTrials.gov study NCT04030598. IPD Sharing: NO. Countries: 2. Publications: 1.
Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects
ClinicalTrials.gov study NCT00707746. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia
ClinicalTrials.gov study NCT05079919. IPD Sharing: YES. Countries: 23. Publications: 2.
Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients
ClinicalTrials.gov study NCT00770146. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease
ClinicalTrials.gov study NCT03070782. IPD Sharing: NO. Countries: 5. Publications: 3.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS-APO(a)Rx in Participants With High Lipoprotein(a)
ClinicalTrials.gov study NCT02160899. IPD Sharing: Not stated. Countries: 5. Publications: 2.
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer
ClinicalTrials.gov study NCT01675128. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)
ClinicalTrials.gov study NCT02292537. IPD Sharing: Not stated. Countries: 10. Publications: 2.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease
ClinicalTrials.gov study NCT02519036. IPD Sharing: Not stated. Countries: 3. Publications: 3.
Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia
ClinicalTrials.gov study NCT00607373. IPD Sharing: Not stated. Countries: 7. Publications: 3.
The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia
ClinicalTrials.gov study NCT02300233. IPD Sharing: NO. Countries: 6. Publications: 2.
A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia
ClinicalTrials.gov study NCT05610280. IPD Sharing: YES. Countries: 14. Publications: 2.
An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia
ClinicalTrials.gov study NCT00694109. IPD Sharing: Not stated. Countries: 7. Publications: 2.
An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy
ClinicalTrials.gov study NCT01703988. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA).
ClinicalTrials.gov study NCT02462759. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension
ClinicalTrials.gov study NCT02639286. IPD Sharing: NO. Countries: 1. Publications: 5.
A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)
ClinicalTrials.gov study NCT01839656. IPD Sharing: Not stated. Countries: 2. Publications: 3.
A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy
ClinicalTrials.gov study NCT02193074. IPD Sharing: Not stated. Countries: 13. Publications: 4.
Global Fire Weather Indices - ISI using overwintered DC start-up
<p>This dataset was developed by Natural Resources Canada using the European Centre for Medium-range Weather Forecasts (ECMWF) ERA5-HRS Reanalysis product (C3S, 2017) as inputs to the Canadian Forest Fire Danger Rating System R Package (Wang et al. 2017). The dataset provides gridded values of the Canadian Fire Weather Index (FWI) System indices of fuel moisture and fire behaviour, including the Fine Fuel Moisture Code (FFMC), Duff Moisture Code (DMC), Drought Code (DC), Initial Spread Index (ISI), Build-Up Index (BUI), Fire Weather Index (FWI), and Daily Severity rating (DSR). Each of these indices are produced using two calculation methods applied at the beginning of fire season start-up. The first method used the default DC value (DC=15) to start-up the FWI System calculation and only accounted for the longest stretch of active fire season each year (as determined by Wotton and Flannigan, 1993). The second method used the overwintered DC value, calculated from the DC value of the last day of the previous fire season and a percentage of overwinter precipitation, and accounted for all periods of fire season throughout the year. We recommend users of this data use indices where DC has been overwintered in regions where the fire season shuts off for winter and where low overwinter precipitation occurs (eg. parts of western Canada, the western US and the Siberian Boreal forest).</p> <p>References:</p> <p>Copernicus Climate Change Service (C3S) (2017): ERA5: Fifth generation of ECMWF atmospheric reanalyses of the global climate . Copernicus Climate Change Service Climate Data Store (CDS), Accessed June 20<sup>th</sup> 2019. <a href="https://cds.climate.copernicus.eu/cdsapp#!/home">https://cds.climate.copernicus.eu/cdsapp#!/home</a></p> <p>Wang, X., Wotton, B. M., Cantin, A. S., Parisien, M. A., Anderson, K., Moore, B., & Flannigan, M. D. (2017). cffdrs: an R package for the Canadian forest fire danger rating system. Ecological Processes, 6(1), 5.</p> <p>Wotton, B. M., & Flannigan, M. D. (1993). Length of the fire season in a changing climate. The Forestry Chronicle, 69(2), 187-192.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.