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674
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ShareScore release 0.9.0
Dataset results
674 results for “Multicentric”
A Phase III, Multicentre, Double-Blind, Placebo-Controlled Withdrawal Study in Patients With Hyperphosphatemia
ClinicalTrials.gov study NCT00416520. IPD Sharing: Not stated. Countries: 11. Publications: 1.
A Randomized Multicentre Study for the Acute Relief of Episodic and Chronic Cluster Headache.
ClinicalTrials.gov study NCT01958125. IPD Sharing: NO. Countries: 4. Publications: 1.
Multicentre Observational Study on the Wound Pain Relief Properties of ORTODERMINA®
ClinicalTrials.gov study NCT03720119. IPD Sharing: NO. Countries: 1. Publications: 9.
Prognosis of Depression in the Elderly (PRODE). A Multicentre, Longitudinal Study of Elderly Depressed Patients.
ClinicalTrials.gov study NCT01952366. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Colistin Methanesulfonate Sodium Inhalation for Prophylaxis of Ventilator-Associated Pneumonia (CIVAP): A Prospective, Multicentre, Double-Blind, Randomized, Placebo-Controlled Trial
ClinicalTrials.gov study NCT06834971. IPD Sharing: YES. Countries: 1. Publications: 13.
Tocilizumab for KSHV-Associated Multicentric Castleman Disease
ClinicalTrials.gov study NCT01441063. IPD Sharing: NO. Countries: 1. Publications: 4.
Multicentre Study to Determine the Feasibility of Using an Integrated Consent Model to Compare Three Standard of Care Regimens for The Treatment of Triple-Negative Breast Cancer in the Neoadjuvant/Adj
ClinicalTrials.gov study NCT02688803. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Prediction of Delivery With Transperineal Ultrasound in Women With Prolonged Labour. Multicentre Study
ClinicalTrials.gov study NCT01610453. IPD Sharing: Not stated. Countries: 4. Publications: 5.
Multicentre ObservatioNal Initiative in Treat to Target Outcomes in Psoriatic Arthritis
ClinicalTrials.gov study NCT03531073. IPD Sharing: NO. Countries: 1. Publications: 1.
A Multicentre, Single-arm, Open-label Safety Study of Lenalidomide Plus Dexamethasone in Previously Treated Subjects With Multiple Myeloma
ClinicalTrials.gov study NCT00420849. IPD Sharing: Not stated. Countries: 5. Publications: 1.
An Multicentre Clinical Study to Evaluate the Usability and Safety of the Pre-filled Pen and Pre-filled Syringe of SB5 in Subjects With Rheumatoid Arthritis
ClinicalTrials.gov study NCT02565810. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Open Label, Multicentre Trial to Assess Safety and Efficacy of ITF2357 in Active Systemic Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT00570661. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial
ClinicalTrials.gov study NCT02406781. IPD Sharing: NO. Countries: 1. Publications: 6.
Open Label, Multicentre Extension Study of Protocol 42603ATT3002 to Evaluate Safety of Prolonged Release OROS Methlyphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
ClinicalTrials.gov study NCT00307684. IPD Sharing: Not stated. Countries: 7. Publications: 2.
Rethinking Pulmonary Rehabilitation - a Three-arm Randomised Multicentre Trial
ClinicalTrials.gov study NCT05664945. IPD Sharing: NO. Countries: 1. Publications: 1.
This Trial is a Randomised, Multicentre, Investigator-blind, Vehicle and Comparator-controlled, Parallel-group Trial With the Purpose of Evaluation Efficacy, Safety and Convenience of the MC2-01 Cream
ClinicalTrials.gov study NCT03802344. IPD Sharing: Not stated. Countries: 2. Publications: 3.
Data from: Evaluating culture-free targeted next-generation sequencing for diagnosing drug-resistant tuberculosis: A multicentre clinical study of two end-to-end commercial workflows
Open the record for dataset details and reuse information.
Data from: A prospective harmonized multicentre DTI study of cerebral white matter degeneration in ALS
<p>Objective: To evaluate progressive white matter (WM) degeneration in ALS.</p> <p>Methods: Sixty-six patients with ALS and 43 healthy controls were enrolled in a prospective, longitudinal, multicentre study in the Canadian ALS Neuroimaging Consortium (CALSNIC). Participants underwent a harmonized neuroimaging protocol across 4 centres including diffusion tensor imaging (DTI) for assessment of WM integrity. Three visits were accompanied by clinical assessments of disability (ALSFRS-R) and upper motor neuron (UMN) function. Voxel-wise whole brain and quantitative tractwise DTI assessments were done at baseline and longitudinally. Correction for site variance incorporated data from healthy controls and from healthy volunteers that underwent the DTI protocol at each centre.</p> <p>Results: ALS patients had a mean progressive decline in fractional anisotropy (FA) of the corticospinal tract (CST) and frontal lobes. Tractwise analysis revealed reduced FA in the CST, corticopontine/corticorubral and corticostriatal tracts. CST FA correlated with UMN function and frontal lobe FA with the ALSFRS-R. A progressive decline in CST FA correlated with a decline in the ALSFRS-R and worsening UMN signs. Patients with fast vs slow progression had a greater reduction in FA of the CST and upper frontal lobe.</p> <p>Conclusions: Progressive WM degeneration in ALS is most prominent in the CST and frontal lobes, and to a lesser degree in the corticopontine/corticorubral tracts and the corticostriatal pathways. With the use of a harmonized imaging protocol and incorporation of analytical methods to address site-related variances, this study is an important milestone towards developing DTI biomarkers for cerebral degeneration in ALS.</p>
Percutaneous transhepatic or endoscopic ultrasound-guided biliary drainage in malignant distal bile duct obstruction using a metal stent: study protocol for a prospective European multicentre trial (PUMa trial)
<p><strong>Abstract:</strong></p> <p><strong>Background</strong></p> <p>Percutaneous transhepatic biliary drainage [PTBD] is still universally used in patients with malignant distal bile duct obstruction when endoscopic retrograde cholangiopancreatography [ERCP] is not successful or not possible to perform. However, endoscopic ultrasound-guided biliary drainage [EUS-BD] was associated with better clinical success and a lower rate of adverse events (AE) in recent comparative studies, although further improvements in the PTBD technique, such as primary stent implantation as a one-step procedure, percutaneous ultrasound-guided bile duct puncture and left-sided bile duct access, were not considered. The aim of this study is to compare both procedures carried out as intended one-step procedures with primary metal stent insertion.</p> <p><strong>Methods</strong></p> <p>The PUMa trial is an ongoing European non-randomized, controlled, parallel group, non-inferiority multicentre trial. Fourteen study centres perform only one of the two procedures with regard to the best local experience. PTBD is performed as a one-step procedure with primary metal stent insertion after percutaneous ultrasound-guided bile duct access. EUS-BD is performed as a one-step procedure using the EUS-guided trans-gastric or trans-duodenal access route for trans-gastric trans-hepatic (EUS-HGS), trans-duodenal (EUS-CDS) or antegrade trans-papillary (EUS-AGS) metal stent insertion. The main target values are the technical and clinical success rates, AEs within 30 days and overall disease-specific survival within 6 months. The calculated total number of cases is 212 patients.</p> <p><strong>Discussion:</strong></p> <p>The PUMa trial investigates whether PTBD is not inferior to EUS-BD in terms of technical and clinical success if primary metal stent insertion is performed as a one-step procedure in both procedures. Differences are expected in the quantity and variety of AEs, number of re-interventions and length of hospital stay.</p> <p><strong>Trial Registration</strong>: ClinicalTrials.gov ID: NCT03546049 (date of registration 22.05.2018)</p>
The viral load monitoring cascade in a resource-limited setting: a prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho
<p>Anonymised dataset for the submitted manuscript "The viral load monitoring cascade in a resource-limited setting: a prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho"</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.