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31
datasets available to search
ShareScore release 0.9.0
Dataset results
31 results for “Patient-specific modeling”
Physician Assessment of the Clinical Utility of a Patient-Specific 3D Electro-Anatomical Heart Model in VT Ablation
ClinicalTrials.gov study NCT04841382. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPS cells (NaPi2Bhigh cells)
GEO Series GSE179899. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modelling (timepoints)
GEO Series GSE269316. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPS cells (SPC positive cells)
GEO Series GSE179898. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Examining patient-specific responses to PARP inhibitors in a novel, human induced pluripotent stem cell-based model of breast cancer
GEO Series GSE272395. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPS cells
GEO Series GSE179900. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Modeling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs
GEO Series GSE248240. Homo sapiens. 43 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Modeling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs [ChIP-seq]
GEO Series GSE248238. Homo sapiens. 37 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Modeling the pathogenesis of Charcot-Marie-Tooth disease type 1A using patient-specific iPSCs
GEO Series GSE97851. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Donor-specific NK cells exert potent cytolytic effector functions against patient-specific leukemic blasts in an IL-7 and IL-15 supplemented humanized NOD/SCID/IL2Rγnull mouse model
GEO Series GSE26268. Homo sapiens. 8 samples. Type: Expression profiling by array.
Data set and 3d model from Emendi M, Sturla F, Ghosh RP, Bianchi M, Piatti F, Pluchinotta FR, Giese D, Lombardi M, Redaelli A, Bluestein D. Patient-Specific Bicuspid Aortic Valve Biomechanics: A Magnetic Resonance Imaging Integrated Fluid-Structure Interaction Approach. Ann Biomed Eng. 2020 Aug 17. doi: 10.1007/s10439-020-02571-4. Epub ahead of print. PMID: 32804291.
<p>Data set and 3d model from Emendi M, Sturla F, Ghosh RP, Bianchi M, Piatti F, Pluchinotta FR, Giese D, Lombardi M, Redaelli A, Bluestein D. Patient-Specific Bicuspid Aortic Valve Biomechanics: A Magnetic Resonance Imaging Integrated Fluid-Structure Interaction Approach. Ann Biomed Eng. 2020 Aug 17. doi: 10.1007/s10439-020-02571-4. Epub ahead of print. PMID: 32804291.</p> <p> </p> <p>This is the abstract:</p> <p>Congenital bicuspid aortic valve (BAV) consists of two fused cusps and represents a major risk factor for calcific valvular stenosis. Herein, a fully coupled fluid-structure interaction (FSI) BAV model was developed from patient-specific magnetic resonance imaging (MRI) and compared against in vivo 4-dimensional flow MRI (4D Flow). FSI simulation compared well with 4D Flow, confirming direction and magnitude of the flow jet impinging onto the aortic wall as well as location and extension of secondary flows and vortices developing at systole: the systolic flow jet originating from an elliptical 1.6 cm<sup>2</sup> orifice reached a peak velocity of 252.2 cm/s, 0.6% lower than 4D Flow, progressively impinging on the ascending aorta convexity. The FSI model predicted a peak flow rate of 22.4 L/min, 6.7% higher than 4D Flow, and provided BAV leaflets mechanical and flow-induced shear stresses, not directly attainable from MRI. At systole, the ventricular side of the non-fused leaflet revealed the highest wall shear stress (WSS) average magnitude, up to 14.6 Pa along the free margin, with WSS progressively decreasing towards the belly. During diastole, the aortic side of the fused leaflet exhibited the highest diastolic maximum principal stress, up to 322 kPa within the attachment region. Systematic comparison with ground-truth non-invasive MRI can improve the computational model ability to reproduce native BAV hemodynamics and biomechanical response more realistically, and shed light on their role in BAV patients' risk for developing complications; this approach may further contribute to the validation of advanced FSI simulations designed to assess BAV biomechanics.</p> <p> </p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.