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Dataset results
988 results for “Platinum”
Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy
ClinicalTrials.gov study NCT01852292. IPD Sharing: UNDECIDED. Countries: 18. Publications: 2.
LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib
ClinicalTrials.gov study NCT01828112. IPD Sharing: UNDECIDED. Countries: 20. Publications: 2.
Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected
ClinicalTrials.gov study NCT04729387. IPD Sharing: YES. Countries: 26. Publications: 1.
Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCL
ClinicalTrials.gov study NCT03631199. IPD Sharing: YES. Countries: 41. Publications: 1.
Immune repertoire sequencing reveals differences in treatment response to camrelizumab plus platinum-based chemotherapy in advanced ESCC
Open the record for dataset details and reuse information.
Platinum pyridine cations: the DFT optimized geometries
<p>The geometries were optimized with the hybrid M06 functional, the mDZP all-electron basis set for platinum atom, and the def2-TZVP basis set for light atoms.</p> <p>Working material for the upcoming article.</p>
Fig. 13 in A New Species of Zambedania (Acari: Heterostigmatina: Pygmephoridae) from the Two Rivers Platinum Mine in South Africa and Notes on the Life-cycle of the Genus
Fig. 13. Zambedania sekhukhunensis sp. n. Male paratype. Leg II (right): dorsal view.
Fig. 15 in A New Species of Zambedania (Acari: Heterostigmatina: Pygmephoridae) from the Two Rivers Platinum Mine in South Africa and Notes on the Life-cycle of the Genus
Fig. 15. Zambedania sekhukhunensis sp. n. Male paratype. Leg IV (left): dorsal view.
Fig. 6 in A New Species of Zambedania (Acari: Heterostigmatina: Pygmephoridae) from the Two Rivers Platinum Mine in South Africa and Notes on the Life-cycle of the Genus
Fig. 6. Zambedania sekhukhunensis sp. n. Female holotype. Leg II (right): dorsal view.
Fig. 18 in A New Species of Zambedania (Acari: Heterostigmatina: Pygmephoridae) from the Two Rivers Platinum Mine in South Africa and Notes on the Life-cycle of the Genus
Fig. 18. Zambedania sekhukhunensis sp. n. Larva paratype. Leg I (right): dorsal view.
Fig. 14 in A New Species of Zambedania (Acari: Heterostigmatina: Pygmephoridae) from the Two Rivers Platinum Mine in South Africa and Notes on the Life-cycle of the Genus
Fig. 14. Zambedania sekhukhunensis sp. n. Male paratype. Leg III (right): dorsal view.
Fig. 16 in A New Species of Zambedania (Acari: Heterostigmatina: Pygmephoridae) from the Two Rivers Platinum Mine in South Africa and Notes on the Life-cycle of the Genus
Fig. 16. Zambedania sekhukhunensis sp. n. Larva paratype. Idiosoma: A- dorsum, B- venter.
Platinum nanoparticle database
<p>This is a database of Pt nanoparticles generated with a GAP interatomic potential for platinum [1]. The files are provided in ASE's extended XYZ format. The database contains the following entries:</p> <ol> <li><strong>NP-DB01.yxz</strong>: 8000 Pt nanoparticles with sizes between 10 and 349 atoms, generated with a "cooking" protocol.</li> <li><strong>NP-DB02.yxz</strong>: 3400 Pt nanoparticles with sizes between 10 and 349 atoms, generated with a "crystallization" protocol.</li> </ol> <p>This is the paper reference for this database:</p> <blockquote> <p><strong>J. Kloppenburg, L. B. Pártay, H. Jónsson, M. A. Caro</strong>. "A general-purpose machine learning Pt interatomic potential for an accurate description of bulk, surfaces and nanoparticles". <a href="https://doi.org/10.1063/5.0143891">J. Chem. Phys. 158, 134704 (2023)</a></p> </blockquote> <p><strong>Protocols</strong></p> <ul> <li>"<strong>Cooking</strong>": annealing at 1500 K for 20 ps from fcc + quenching down to 100 K over 20 ps + geometry relaxation to local minimum.</li> <li>"<strong>Crystallization</strong>": annealing at 1150 K for 20 ps from a random spherical distribution + quenching down to 100 K over 20 ps + geometry relaxation to local minimum.</li> </ul> <p><strong>References</strong></p> <ol> <li>J. Kloppenburg and M.A. Caro. General-purpose GAP potential for platinum. DOI: <a href="https://doi.org/10.5281/zenodo.7415219">10.5281/zenodo.7415219</a>.</li> </ol>
General-purpose GAP potential for platinum
<p><strong>Gaussian approximation potential</strong> (GAP) [1] for <strong>platinum</strong>. It has been fitted with <strong>QUIP/GAP </strong>[1,2] by generating a new database of atomic structures containing:</p> <ol> <li>dimers;</li> <li>fcc, bcc, hcp and simple-cubic supercells, including strained, distorted and high-temperature configurations;</li> <li>surface slabs;</li> <li>clusters (nanoparticles).</li> </ol> <p>Version 2 of this potential included more clusters in the training set than version 1.</p> <p>The calculations were carried out at the <strong>PBE</strong> level of theory [3] using the VASP code [4,5]. This potential uses <strong>2-body</strong> (distance_2b) and <strong>SOAP-type descriptors</strong> (soap_turbo) [6,7]. The files can be used both with QUIP/GAP (compiled with the soap_turbo libraries) and <strong>TurboGAP</strong> [8]. This is the reference publication for this potential:</p> <blockquote> <p><strong>J. Kloppenburg, L. B. Pártay, H. Jónsson, M. A. Caro</strong>. "A general-purpose machine learning Pt interatomic potential for an accurate description of bulk, surfaces and nanoparticles". <a href="https://doi.org/10.1063/5.0143891">J. Chem. Phys. <strong>158</strong>, 134704 (2023)</a></p> </blockquote> <p><strong>References</strong></p> <ol> <li>A.P. Bartók, M.C. Payne, R. Kondor, and G. Csányi. Phys. Rev. Lett. 104, 136403 (2010).</li> <li>LibAtoms: <a href="https://libatoms.github.io/">https://libatoms.github.io</a></li> <li>J.P. Perdew, K. Burke and M. Ernzerhof. Phys. Rev. Lett. 77, 3865 (1996).</li> <li>VASP: <a href="http://vasp.at/">http://vasp.at</a></li> <li>G. Kresse and J. Furthmüller. Phys. Rev. B 54, 11169 (1996).</li> <li>A.P. Bartók, R. Kondor, and G. Csányi. Phys. Rev. B 87, 184115 (2013).</li> <li>M.A. Caro. Phys. Rev. B 100, 024112 (2019).</li> <li>TurboGAP: <a href="http://turbogap.fi/">http://turbogap.fi</a></li> </ol>
Dataset from Nature Materials paper: Amorphous nickel hydroxide shell tailors local chemical environment on platinum surface for alkaline hydrogen evolution reaction
<p>Dataset of the paper "Amorphous nickel hydroxide shell tailors local chemical environment on platinum surface for alkaline hydrogen evolution reaction" accepted in Nature Materials.</p> <p>- GCGA_inputs.zip: A zip file containing all needed input files to run a grand canonical genetic algorithm (GCGA) global optimization structure search. Note that the script would need modifications to be compatible with later version of the GOCIA package, please following the most updated instructions at https://github.com/zishengz/gocia</p> <p>- GCGA_Ni12OxHy_all_samples.db: An ASE database file containing all unique structures from the GCGA search of Ni12OxHy on a Pt(111) surface. </p> <p>- GM_Ni12O25H13.vasp: The structure of the global minimum structure from GCGA search, which is also the surface structure we focused on in this study, in VASP structure format.</p> <p>- rxn_structures.zip: A zip file containing the structures of reaction intermediates investigated in this work, in VASP structure format</p> <p> </p>
Ojeok-san Enhances Platinum Sensitivity in Ovarian Cancer by Regulating Adipocyte Paracrine IGF1 Secretion
<p><strong>Figure 1 Adipocytes promote platinum drug resistance in OvCa cells</strong></p> <p>(A-B) The effects of Adipo-CM treatment on cell viability and apoptosis level were detected by CCK-8 and flow cytometry. (C) The expression of proliferation-related and apoptosis-related proteins was detected by western blot. (D) The IC<sub>50</sub> values of different concentrations of cisplatin and carboplatin treatment on OvCa cells were detected by CCK-8. * <em>p</em><0.05.</p> <p> </p> <p><strong>Figure 2 Adipocytes promote OvCa resistance to platinum drugs through paracrine secretion of IGF1</strong></p> <p>(A) The expression of IGF1 in HPAd cells was detected by western blot. (B) The concentration of IGF1 in culture media of HPAd cells was detected by ELISA. (C-D) The effects of different treatments on SKOV3 cell viability and apoptosis level were detected by CCK-8 and flow cytometry. (E) The expression of proliferation-related and apoptosis-related proteins was detected by western blot. (F) The IC<sub>50</sub> values of different concentrations of cisplatin and carboplatin treatment on SKOV3 cells were detected by CCK-8. *VS oe-NC+DMSO, #VS oe-IGF1+DMSO, * <em>p</em><0.05.</p> <p> </p> <p><strong>Figure 3 OJS inhibits adipocyte paracrine secretion of IGF1 to regulate OvCa progression</strong></p> <p>(A-B) The expression of IGF1 in HPAd cells and cell culture supernatant was detected by western blot and ELISA, respectively. (C-D) The effects of different treatments on SKOV3 cell viability and apoptosis level were detected by CCK-8 and flow cytometry. (E) The expression of proliferation-related and apoptosis-related proteins was detected by western blot. (F) The IC<sub>50</sub> values of different concentrations of cisplatin and carboplatin treatment on SKOV3 cells were detected by CCK-8. *VS Adipo-CM, #VS Adipo-CM2, <em>p</em><0.05.</p> <p> </p> <p><strong>Figure 4 OJS enhances the anticancer activity of cisplatin in SKOV3 and HPAd xenograft models</strong></p> <p>(A-C) Tumor growth under different treatments. (D) The effects of OJS and cisplatin on the damage and morphological changes of major organs in mice were detected by H&E staining. (E) The expression of proliferation-related and apoptosis-related proteins was detected by IHC. *VS control, #VS cisplatin, <em>p</em><0.05.</p> <p> </p>
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of Long De Novo Coronary Artery Lesions (PLATINUM LL)
ClinicalTrials.gov study NCT01500434. IPD Sharing: UNDECIDED. Countries: 7. Publications: 2.
Vorinostat, Carboplatin and Gemcitabine in Women With Recurrent, Platinum-Sensitive Ovarian Cancer
ClinicalTrials.gov study NCT00910000. IPD Sharing: NO. Countries: 1. Publications: 1.
Temsirolimus (Torisel®) and Erlotinib (Tarceva®) in Platinum-Refractory/Ineligible, Advanced, Squamous Cell Carcinoma
ClinicalTrials.gov study NCT01009203. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Chemotherapy With Pemetrexed in Combination With Platinum for Advanced Non-Small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov study NCT00402051. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.