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111 results for “Saponins”
Fig. 7 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 7. QRT-PCR validation of RNA-Seq data. Expression profiles of eight selected genes were determined by transcriptome and qRT-PCR data. The left vertical axis represents the relative expression of the gene based on qRT-PCR. The right vertical axis represents the expression level of the gene based on transcriptome sequencing. The asterisk above the bar chart denotes statistical significance based on the qRT-PCR data (* denotes P value <0.05, ** denotes P value <0.01, ns denotes P value> 0.05).
Fig. 1 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 1. The bioactive compound content and transcriptome characters. (a) Total content of three typical types of Paris saponins in leaves and rhizomes during the vegetative and fruiting stages. VL: leaves at vegetative stage, VR: rhizomes at vegetative stage, FL: leaves at fruiting stage, and FR: rhizomes at fruiting stage. (b) Proportion of three types of Paris saponins in leaves and rhizomes. (c) Distribution of the expressed unigenes in tissues during the two stages (log2 (TPMþ1)> 0). (d) Boxplot of unigene expression profiles.
Fig. 3 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 3. DEG statistics. (a) Venn diagram of DEGs from the four paired comparisons. (b) The number of up-down regulated DEGs of the four paired comparisons.
Fig. 1 in Dammarane-type triterpenoid saponins from Salvia russellii Benth.
Fig. 1. The chemical structures of dammarane-type triterpenoid saponins (1–3) from the aerial parts of S. russellii Benth.
Fig. 5 in Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities
Fig. 5. Apoptosis induced by 9 in MCF-7 cells. [Q3: The early stage of apoptosis (FITC positive, PI negative) Q2: The late stage of apoptosis (FITC positive, PI positive) Q4: The live cells (FITC negative, PI negative)].
Fig. 4 in Bioactive dammarane triterpenoid saponins from the leaves of Cyclocarya paliurus
Fig. 4. Plots of ν versus the concentration of α-glucosidase of 4 (A), 9 (B), 10 (C), 11 (D) and acarbose (E), and Lineweaver Burk plots for α-glucosidase inhibition of 4 (F), 9 (G), 10 (H), 11 (I) and acarbose (J).
Fig. 5 in Bioactive dammarane triterpenoid saponins from the leaves of Cyclocarya paliurus
Fig. 5. Docking simulation of the binding position of 4 (A) and 10 (A′); Corresponding secondary structures of α-glucosidase interact with 4 (B) and 10 (B′). Corresponding amino acid residues of α-glucosidase interacted with 4 (C) and 10 (C′). The short dotted yellow line stands for hydrogen bonds. The purple stick structures were used to represent 4 and the aurantium stick structures were used to represent 10 while the green stick denotes the residues of α-glucosidase. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3 in Triterpene saponins from the seeds of Erythrophleum fordii and their cytotoxic activities
Fig. 3. Key NOE correlations (red dotted double arrows and blue dotted double arrows) of aglycones of 2–4. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2 in Anti-adipogenic 18,19-seco-ursane stereoisomers and oleane-type saponins from Ilex cornuta leaves
Fig. 2. HPLC separation of compounds 1–3 and 6 (A, a mixture of 1–3 and 6; B, compound 1; C, compound 6; D, compound 2; and E, compound 3). HPLC conditions: an Agilent 1100 series system with a Capcell Pak MGII C18 column (4.6 mm × 250 mm, 5 μm); column temperature, 25 °C, the mobile phase: MeCN-H2O (33:67); flow rate: 1.0 mL/min; detection wavelength, 210 nm.
Fig. 5 in Anti-adipogenic 18,19-seco-ursane stereoisomers and oleane-type saponins from Ilex cornuta leaves
Fig. 5. The inhibitory effect of compounds 1–16 on the PPARγ expression in transfected 3T3-L1-Lenti- PPARγ-Luc cells (n = 4, *: comparison of PPARγ expression with the vehicle control group, #: comparison of PPARγ expression with the positive control, ** P ≤ 0.01, *** P ≤ 0.001). Con and PC represented the vehicle control group (cells treated with 0.1% DMSO) and the positive control (T0070907) at 5 μM, respectively. 1–16 represented compounds 1–16 at 5 μM. Vertical bars represented the standard error of means (SEM).
Fig. 1 in Triterpenic saponins from Medicago marina L
Fig. 1. Structure of M. marina saponins 1–11. I, zanhic acid; II, medicagenic acid; III, soyasapogenol B; IV, soyasapogenol E; Api: β-D-apiofuranosyl; Ara: α-Larabinopyranosl; Glc:β-D-glucopyranosyl; GluA: β-D-glucuronopyranosyl; Rha: α-L-rhamnopyranosyl; Xyl: β-D-xylopyranosyl.
Fig. 3 in Reinvestigation of Herniaria glabra L. saponins and their biological activity
Fig. 3. Selected key NOE correlations (red dotted arrows) of aglycones of 2 (A) and of 12 (B). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Figure 1 from: Kondeva-Burdina M, Krasteva I, Popov G, Manov V (2019) Neuroprotective and antioxidant activities of saponins' mixture from Astragalus glycyphylloides in a model of 6-hydroxydopamine-induced oxidative stress on isolated rat brain synaptosomes. Pharmacia 66(4): 233-236. https://doi.org/10.3897/pharmacia.66.e37997
Figure 1 Effects of PSM and S on synaptosomal viability in conditions of 6-OHDA-induced oxidative stress; ***P ≤ 0.001 vs control (non-treated synaptosomes); +P ≤ 0.05, ++P ≤ 0.01, +++P ≤ 0.001 vs6-OHDA.
Figure 2 from: Kondeva-Burdina M, Krasteva I, Popov G, Manov V (2019) Neuroprotective and antioxidant activities of saponins' mixture from Astragalus glycyphylloides in a model of 6-hydroxydopamine-induced oxidative stress on isolated rat brain synaptosomes. Pharmacia 66(4): 233-236. https://doi.org/10.3897/pharmacia.66.e37997
Figure 2 Effects of PSM and S on GSH level in conditions of 6-OHDA-induced oxidative stress ***P ≤ 0.001 vs control (non-treated synaptosomes); +P ≤ 0.05, ++P ≤ 0.01 vs6-OHDA.
Figure 4 from: Shkondrov A, Kondeva-Burdina M, Stambolov I, Krasteva I (2024) Activity of an oleanane-type tritrepenoid saponin from A. glycyphyllos on human recombinant MAO enzymes. Pharmacia 71: 1-6. https://doi.org/10.3897/pharmacia.71.e114786
Figure 4 Effect of Sg and Selegiline (at concentrations of 0.050, 0.250, 0.500, 0.750, and 1 μM) on human recombinant MAOA enzyme (hMAOB) activity. ** P < 0.01; *** P < 0.001 vs. control (pure hMAOB).
Figure 3 from: Shkondrov A, Kondeva-Burdina M, Stambolov I, Krasteva I (2024) Activity of an oleanane-type tritrepenoid saponin from A. glycyphyllos on human recombinant MAO enzymes. Pharmacia 71: 1-6. https://doi.org/10.3897/pharmacia.71.e114786
Figure 3 Effect of Sg and Chlorgyline (at concentrations of 0.050, 0.250, 0.500, 0.750, and 1 μM) on the activity (%) of human recombinant MAOA enzyme (hMAOA). * P < 0.05; ** P < 0.01; *** P < 0.001 vs. control (pure hMAOA).
Fig. 2. Key HMBC and ROESY correlations for compound 1 in Triterpenoid saponins from Anagallis monelli ssp. linifolia (L.) Maire and their chemotaxonomic significance
Fig. 2. Key HMBC and ROESY correlations for compound 1.
Fig. 4 in Triterpenoid saponins from Anagallis monelli ssp. linifolia (L.) Maire and their chemotaxonomic significance
Fig. 4. The common carbohydrate chain linked on the C-3 of 13,28-epoxy- 3,16-oleananediol.
Fig. 3. Key HMBC correlations for compound 10 in Triterpenoid saponins from Anagallis monelli ssp. linifolia (L.) Maire and their chemotaxonomic significance
Fig. 3. Key HMBC correlations for compound 10.
Supplementary material 1 from: Enchev P, Zarev Y, Michler H, Ionkova I (2023) Production of rare cycloartane saponins from Astragalus thracicus (Griseb) compared to Astragalus membranaceus (Fisch.) Bunge – native and biotechnological sources. Pharmacia 70(1): 73-77. https://doi.org/10.3897/pharmacia.70.e97782
HR-ESI-MS of Astragaloside I, Astragaloside II and Astragaloside IV
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