Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
69
datasets available to search
ShareScore release 0.9.0
Dataset results
69 results for “Screening assays”
Investigating a Von Willebrand Factor (VWF) Functional Screening Assay for Assigning the Phenotypic Variants of Von Willebrand Disease (VWD)
ClinicalTrials.gov study NCT02466789. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Screening for Monoclonal Gammopathy in Individuals Undergoing Physical Examinations Using iMS-LC Assay Technology.
ClinicalTrials.gov study NCT06489613. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Detection of Abnormal Respiratory Cell Populations in Lung Cancer Screening Patients Using the CyPath Lung Assay
ClinicalTrials.gov study NCT05870592. IPD Sharing: NO. Countries: 1. Publications: 5.
Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing
ClinicalTrials.gov study NCT01600209. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
ClinicalTrials.gov study NCT04968548. IPD Sharing: NO. Countries: 2. Publications: 1.
Diagnostic Performance of the ID Now™ COVID-19 Screening Test Versus Simplexa™ COVID-19 Direct Assay
ClinicalTrials.gov study NCT04785898. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Buccal Screening Evaluation Using an RT-PCR Assay and a Rapid ELISA Test Among Symptomatic and Asymptomatic Patients
ClinicalTrials.gov study NCT05074745. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Development of a genotype-by-sequencing immunogenetic assay as exemplified by screening for variation in red fox with and without endemic rabies exposure
Open the record for dataset details and reuse information.
Chemical screening in an estrogen receptor transactivation assay with metabolic competence
Open the record for dataset details and reuse information.
Data from: Screening of cytotoxic or cytostatic flavonoids with quantitative FUCCI-based cell cycle assay
The Fluorescence-Ubiquitin Cell Cycle Indicator (FUCCI) system can be used not only to study gene expression at a specific cell cycle stage, but also to monitor cell cycle transitions in real time. In this study, we used a single clone of FUCCI-expressing HeLa cells (FUCCI-HeLa cells) and monitored the cell cycle in individual live cells over time by determining the ratios between red fluorescence (RF) of RFP-Cdt1 and green fluorescence (GF) of GFP-Geminin. Cytotoxic and cytostatic compounds, the latter of which induced G2 or mitotic arrest, were identified based on periodic cycling of the RF/GF and GF/RF ratios in FUCCI-HeLa cells treated with anticancer drugs. With this cell cycle monitoring system, ten flavonoids were screened. Of these, apigenin and luteolin, which have a flavone backbone, were cytotoxic, whereas kaempferol, which has a flavonol backbone, was cytostatic and induced G2 arrest. In summary, we developed a system to quantitatively monitor the cell cycle in real time. This system can be used to identify novel compounds that modulate the cell cycle and to investigate structure–activity relationships.
Data from: Screening of candidate substrates and coupling ions of transporters by thermostability shift assays
Substrates of most transport proteins have not been identified, limiting our understanding of their role in physiology and disease. Traditional identification methods use transport assays with radioactive compounds, but they are technically challenging and many compounds are unavailable in radioactive form or are prohibitively expensive, precluding large-scale trials. Here, we present a high-throughput screening method that can identify candidate substrates from libraries of unlabeled compounds. The assay is based on the principle that transport proteins recognize substrates through specific interactions, which lead to enhanced stabilization of the transporter population in thermostability shift assays. Representatives of three different transporter (super)families were tested, which differ in structure as well as transport and ion coupling mechanisms. In each case, the substrates were identified correctly from a large set of chemically related compounds, including stereo-isoforms. In some cases, stabilization by substrate binding was enhanced further by ions, providing testable hypotheses on energy coupling mechanisms.
Evaluation of Chagas Blood Screening and Confirmatory Assays
ClinicalTrials.gov study NCT00718042. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Studies of Endometrial Cytology and Cervical Methylation Assays in Endometrial Cancer Screening and Fertility-Preservation Evaluation
ClinicalTrials.gov study NCT06672341. IPD Sharing: Not stated. Countries: 0. Publications: 17.
Evaluation of a Human Immunodeficiency Virus (HIV) Blood Screening Assay
ClinicalTrials.gov study NCT00686205. IPD Sharing: Not stated. Countries: 1. Publications: 0.
CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung
ClinicalTrials.gov study NCT05306288. IPD Sharing: UNDECIDED. Countries: 2. Publications: 0.
Lipidomics Screening of Celecoxib in ex Vivo Human Whole Blood Assay - Part B
ClinicalTrials.gov study NCT02413203. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Abbott Laboratories Alinity s Blood Screening Assays - Clinical Evaluation Protocol
ClinicalTrials.gov study NCT03285295. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Screening of cytotoxic or cytostatic flavonoids with quantitative FUCCI-based cell cycle assay
Open the record for dataset details and reuse information.
Data from: Screening of candidate substrates and coupling ions of transporters by thermostability shift assays
Open the record for dataset details and reuse information.
A massively parallel reporter assay library to screen short synthetic promoters in mammalian cells
GEO Series GSE271608. Homo sapiens; Mesocricetus auratus; synthetic construct; Mus musculus. 65 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.