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126 results for “TEMPORAL LOBE”
Dataset related to article CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy
<p>Raw data are organized in an excel file where for each figure (included supll. figures) data are listed in a different sheet.</p>
Structure-function coupling increases during interictal spikes in temporal lobe epilepsy: a graph signal processing study
<p><strong>Dataset for the publication: 'Structure-function coupling increases during interictal spikes in temporal lobe epilepsy: a graph signal processing study'<br> Rigoni et al. 2023, Clinical Neurophysiology, doi: </strong><a href="https://doi.org/10.1016/j.clinph.2023.05.012">https://doi.org/10.1016/j.clinph.2023.05.012</a></p> <p><strong>Dataset description</strong></p> <p><em>func_data.mat</em> : source-reconstructed EEG traces stored in a Fieldtrip format (data for each subj)</p> <p><em>struct_data</em>: consensus structural connectome</p> <p><em>ROIpatch </em>: mesh used to plot Fig4</p> <p><em>SC_surrogates (W0)</em>: 1000 degree-preserving surrogates of the structural connectome computed with the null_model_und_sign function of the Brani Connectivity Toolbox; W0 are used for broadcasting analyses, section 2.6.2</p> <p><em>SC_surrogates_harmonics (U0)</em> : network harmonics of the surrogate structural connectomes (W0); U0 are used for broadcasting analyses, section 2.6.2<br> <em>BD_surr </em>: Broadcasting-direction (BD) of the degree-preserving surrogates of the structural connectome W0; used to produce FigS3 (data for each subj)</p> <p><em>PHI </em>: matrix of +1/-1 to generate the functional surrogates used to define significance of SDI, as described in section 2.6.3</p> <p><em>data_GSP2_surr </em>: SDI of the functional surrogates used to define significance of SDI, as described in section 2.6.3 (data for each subj)</p> <p> </p> <p>Abbreviations:</p> <p>EEG= electroencephalography;</p> <p>SDI= structure-decoupling index</p>
Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT06558890. IPD Sharing: NO. Countries: 1. Publications: 15.
Minimally Invasive Surgical Epilepsy Trial for Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT05019404. IPD Sharing: NO. Countries: 1. Publications: 16.
Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients
ClinicalTrials.gov study NCT05339438. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT00916266. IPD Sharing: Not stated. Countries: 1. Publications: 5.
CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients
ClinicalTrials.gov study NCT02262156. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
ClinicalTrials.gov study NCT05135091. IPD Sharing: NO. Countries: 1. Publications: 1.
Study of [11C]DPA-713 for Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT01793532. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis
ClinicalTrials.gov study NCT01865201. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Autonomic Dysfunction in Temporal Lobe Epilepsy and SUDEP
ClinicalTrials.gov study NCT06269822. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT04897776. IPD Sharing: NO. Countries: 1. Publications: 5.
Effects of tDCS on Depressive Symptoms of Participants With Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT03871842. IPD Sharing: NO. Countries: 1. Publications: 1.
Advanced Magnetic Resonance Imaging in Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT03643471. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT02151175. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT04164056. IPD Sharing: NO. Countries: 1. Publications: 2.
GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression
ClinicalTrials.gov study NCT00931619. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Data from: Dataset of human medial temporal lobe single neuron activity during declarative memory encoding and recognition
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Single nucleus sequencing analysis of rat hippocampus reveals the landscape of latent phase temporal lobe epilepsy
Open the record for dataset details and reuse information.
The cost effectiveness of surgery for drug resistant temporal lobe epilepsy in the US
<p><strong>Objective:</strong> Surgery is an effective but costly treatment for many patients with drug resistant temporal lobe epilepsy (DR-TLE). We aim to evaluate whether, in the United States, 1) surgery is cost-effective compared to medical management for patients deemed surgical candidates, 2) surgical evaluation is cost-effective for DR-TLE patients in general.</p> <p><strong>Methods:</strong> We use a semi-Markov model to assess the cost-effectiveness of surgery and surgical evaluation over a lifetime horizon. We use 2<sup>nd</sup> order Monte Carlo simulations to conduct probabilistic sensitivity analyses to estimate variation in model output. We adopt both healthcare and societal perspectives, including direct healthcare costs (e.g. surgery, AEDs) and indirect costs (e.g. lost earnings by patients and care providers.) We compare incremental cost-effectiveness ratio (ICER) to societal willingness-to-pay (~$100,000 per Quality Adjusted Life Year) to determine whether surgery is cost-effective.</p> <p><strong>Results:</strong> Epilepsy surgery is cost effective compared to medical management in surgically eligible patients by virtue of being cost saving ($328K vs. 423K) and more effective (16.6 QALY vs. 13.6 QALY) than medical management in the long run. Surgical evaluation is cost-effective in DR-TLE patients even if the probability of being deemed a surgical candidate is only 5%. From a societal perspective, surgery becomes cost effective within 3 years and 89% of simulations favor surgery over the lifetime horizon.</p> <p><strong>Conclusion:</strong> For surgically eligible DR-TLE patients, surgery is cost-effective. For DR-TLE patients in general, referral for surgical evaluation (and possible subsequent surgery) is cost-effective. DR-TLE patients should be referred for surgical evaluation without hesitation on cost-effectiveness grounds.</p>
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.