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329 results for “Taste”
Shifting Salty Taste Preferences in Children
ClinicalTrials.gov study NCT02909764. IPD Sharing: NO. Countries: 1. Publications: 1.
Changes in Taste and Eating Habits Associated With GLP-1 Agonists in Weight Loss Patients
ClinicalTrials.gov study NCT07229170. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Differential Responses to Drugs and Sweet Tastes
ClinicalTrials.gov study NCT03810703. IPD Sharing: NO. Countries: 1. Publications: 21.
Evaluation of Taste Sensation Changes During Fixed Orthodontic Treatment
ClinicalTrials.gov study NCT06989736. IPD Sharing: NO. Countries: 1. Publications: 1.
Evaluation of Smell and Taste in Fibromyalgia
ClinicalTrials.gov study NCT03823937. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Lowered sensitivity of bitter taste receptors to β-glucosides in bamboo lemurs: An instance of parallel and adaptive functional decline in TAS2R16?
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Taste aversion training can educate free-ranging crocodiles against toxic invaders
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Data from: Predators' consumption of unpalatable prey does not vary as a function of bitter taste perception
<p>Many prey species contain defensive chemicals that are described as tasting bitter. Bitter taste perception is therefore assumed to be important when predators are learning about prey defenses. However, it is not known how individuals differ in their response to bitter taste, and how this influences their foraging decisions. We conducted taste perception assays in which wild-caught great tits (<i>Parus major</i>) were given water with increasing concentrations of bitter-tasting chloroquine diphosphate until they showed an aversive response to bitter taste. This response threshold was found to vary considerably among individuals, ranging from chloroquine concentrations of 0.01 mmol/l to 8 mmol/l. We next investigated whether the response threshold influenced the consumption of defended prey during avoidance learning by presenting birds with novel palatable and defended prey in a random sequence until they refused to attack defended prey. We predicted that individuals with taste response thresholds at lower concentrations would consume fewer defended prey before rejecting them, but found that the response threshold had no effect on birds' food choices. Instead, willingness to consume defended prey was influenced by birds' body condition. This effect was age and sex dependent, with adult males attacking more defended prey when their body condition was poor, whereas body condition did not have an effect on the foraging choices of juveniles and females. Together, our results suggest that even though taste perception might be important for recognizing prey toxicity, other factors, such as predators' energetic state, drive the decisions to consume chemically defended prey.</p>
Komarov et al., Food Hardness Preference Reveals Multisensory Contributions of Taste Organs - Raw data
<p><span>The folders are structured as follows: ‘Charts’ contains an excel file, with sheets separated by figure all the datapoints presented in all boxplots presented in the figures. ‘Calcium imaging’ contains the raw fluorescence values for the traces presented in the figures, along with the accompanying R scripts used for analysis. ‘Single Cell RNAseq’ contains the metadata and analysis scripts for the single-cell RNA sequencing data presented in this paper. The full raw datasets may be accessed from NCBI Gene Expression Omnibus (accession number GSE149975) <span> </span></span></p>
Data from: Synergism, bifunctionality, and the evolution of a gradual sensory trade-off in hummingbird taste receptors
<p>Sensory receptor evolution can imply trade-offs between ligands, but the extent to which such trade-offs occur and the underlying processes shaping their evolution is not well understood. For example, hummingbirds have re-purposed their ancestral savory receptor (T1R1-T1R3) to detect sugars, but the impact of this sensory shift on amino acid perception is unclear. Here, we use functional and behavioral approaches to show that the hummingbird T1R1-T1R3 acts as a bifunctional receptor responsive to both sugars and amino acids. Our comparative analyses reveal substantial functional diversity across the hummingbird radiation and suggest an evolutionary timeline for T1R1-T1R3 re-tuning. Finally, we identify a novel form of synergism between sugars and amino acids in vertebrate taste receptors. This work uncovers an unexplored axis of sensory diversity, suggesting new ways in which nectar chemistry and pollinator preferences can coevolve.</p>
Orbitrap analysed non-volatile compound data from blue swimmer crab (Portunus armatus) flesh for manuscript: "Climate-driven changes to taste and aroma determining metabolites in an economically valuable portunid (Portunus armatus) have implications for future harvesting"
<p>Accurate mass measurements of non-volatile metabolites conducted on a Q-Exactive Orbitrap LC-MS (Thermo Scientific, Scoresby, VIC, Australia) equipped with a heated electrospray ionization (H-ESI) source. Source conditions were as follows: spray voltage (positive ion 3.9 kV), sheath gas 60 (arbitrary units), auxiliary gas 10 (arbitrary units) and sweep gas 1 (arbitrary units), capillary temperature of 350 °C and auxiliary gas heating temperature of 400 °C.</p>
Bitter taste receptor genes of primates
<p><span>Bitter taste perception plays a critical role in deterring animals from consuming harmful and toxic substances. To characterize the evolution of primate <em>Tas2r</em>s and test whether dietary preference has shaped the <em>Tas2r</em>s repertoire of primates, we identified <em>Tas2r</em> genes of 35 genomes including 16 Cercopithecidae species, 6 Hominidae species, 4 Cebidae species, 3 Lemuridae species, and other 6 species. The results showed that the total numbers of primates' <em>Tas2r</em>s ranged from 27 to 51, which concentrated on 2–4 scaffolds of each species and the closely related genes tandemly duplicated in the same scaffold. Phylogenetic construction revealed that the <em>Tas2r</em> genes can be divided into 21 clades, among which, anthropoid-specific clades, Prosimii-specific clade, clades with multiple gene copies, or even Cercopithecidea-specific <em>Tas2r</em>s were detected. In addition, phylogenetically independent contrast (PIC) analysis revealed that the number of intact <em>Tas2r</em>s was significantly correlated with feeding preferences. Altogether, our data supported diet as a driving force of primate <em>Tas2r</em>s evolution, and Cercopithecidae species have developed some specific <em>Tas2r</em>s during the evolutionary process. These results are probably because most Cercopithecidae species feed on plants containing many toxins, and it is necessary to develop specialized <em>Tas2r</em>s to protect them from poisoning.</span></p>
Figure 2 in Larvae of pyrrhocorid true bugs are not to spiders' taste: putative Müllerian mimicry
Figure 2. Attack rates (mean ± SE; dotted lines) and capture rates (mean ± SE; full lines) during five trials of the avoidancelearning test. Pink squares, Pyrrhocoris (N = 50; RaŠka et al., 2017); blue circles, Scantius (N = 50); white diamonds, control fruit flies (N = 25).
Figure 1 in Larvae of pyrrhocorid true bugs are not to spiders' taste: putative Müllerian mimicry
Figure 1. Adults of the firebug Pyrrhocoris apterus (A) and the red bug Scantius aegyptius (B), and third-instar larvae of both species – the firebug (C) and the red bug (D). Scale bar = 1 mm.
Figure 4 in Larvae of pyrrhocorid true bugs are not to spiders' taste: putative Müllerian mimicry
Figure 4. Attack rates (mean ± SE; open bars connected with dotted lines) and capture rates (mean ± SE; coloured bars connected with full lines) during presentation of the same prey in the first and the last trial of the prolonged avoidancelearning test (trials 1 and 8) and in the memory test on the second day (trial 9). Pink, Pyrrhocoris (N = 25; RaŠka et al., 2017); blue, Scantius (N = 25).
Sensory Evaluation of the Taste of Pediatric Medicines
ClinicalTrials.gov study NCT03627351. IPD Sharing: YES. Countries: 1. Publications: 7.
Changes in Sensitivity, Taste and Smell in Stroke Patients
ClinicalTrials.gov study NCT03240965. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Does Sweet Taste Potentiate Nicotine Cue Reactivity?
ClinicalTrials.gov study NCT02499757. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Umami Taste Intensity and ad Libitum Meal Intake
ClinicalTrials.gov study NCT07059117. IPD Sharing: YES. Countries: 1. Publications: 7.
Taste Alterations Study
ClinicalTrials.gov study NCT06669416. IPD Sharing: NO. Countries: 1. Publications: 9.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.