Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
98
datasets available to search
ShareScore release 0.9.0
Dataset results
98 results for “Temporal Lobe Epilepsy”
Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT02151175. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT04164056. IPD Sharing: NO. Countries: 1. Publications: 2.
GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression
ClinicalTrials.gov study NCT00931619. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Single nucleus sequencing analysis of rat hippocampus reveals the landscape of latent phase temporal lobe epilepsy
Open the record for dataset details and reuse information.
The cost effectiveness of surgery for drug resistant temporal lobe epilepsy in the US
<p><strong>Objective:</strong> Surgery is an effective but costly treatment for many patients with drug resistant temporal lobe epilepsy (DR-TLE). We aim to evaluate whether, in the United States, 1) surgery is cost-effective compared to medical management for patients deemed surgical candidates, 2) surgical evaluation is cost-effective for DR-TLE patients in general.</p> <p><strong>Methods:</strong> We use a semi-Markov model to assess the cost-effectiveness of surgery and surgical evaluation over a lifetime horizon. We use 2<sup>nd</sup> order Monte Carlo simulations to conduct probabilistic sensitivity analyses to estimate variation in model output. We adopt both healthcare and societal perspectives, including direct healthcare costs (e.g. surgery, AEDs) and indirect costs (e.g. lost earnings by patients and care providers.) We compare incremental cost-effectiveness ratio (ICER) to societal willingness-to-pay (~$100,000 per Quality Adjusted Life Year) to determine whether surgery is cost-effective.</p> <p><strong>Results:</strong> Epilepsy surgery is cost effective compared to medical management in surgically eligible patients by virtue of being cost saving ($328K vs. 423K) and more effective (16.6 QALY vs. 13.6 QALY) than medical management in the long run. Surgical evaluation is cost-effective in DR-TLE patients even if the probability of being deemed a surgical candidate is only 5%. From a societal perspective, surgery becomes cost effective within 3 years and 89% of simulations favor surgery over the lifetime horizon.</p> <p><strong>Conclusion:</strong> For surgically eligible DR-TLE patients, surgery is cost-effective. For DR-TLE patients in general, referral for surgical evaluation (and possible subsequent surgery) is cost-effective. DR-TLE patients should be referred for surgical evaluation without hesitation on cost-effectiveness grounds.</p>
Seizure and Anatomical Outcomes of Repeat Laser Amygdalohippocampotomy for Temporal Lobe Epilepsy: A Single-Institution Case Series
<p>Subject imaging data.</p>
Language and Emotional Function in Patients With Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT00081432. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Stereotactic Laser Ablation for Temporal Lobe Epilepsy (Slate)
ClinicalTrials.gov study NCT02844465. IPD Sharing: NO. Countries: 1. Publications: 0.
MRI Volumetry and Diffusion Tensor Imaging in Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT07384351. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Focused Ultrasound Neuromodulation for Treatment of Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT03657056. IPD Sharing: NO. Countries: 0. Publications: 13.
The cost effectiveness of surgery for drug resistant temporal lobe epilepsy in the US
Open the record for dataset details and reuse information.
Data from: Temporal lobe epilepsy: hippocampal pathology modulates white matter connectome topology and controllability
Open the record for dataset details and reuse information.
Dual-center, dual-platform microRNA profiling identifies plasma biomarkers of adult temporal lobe epilepsy (Beaumont)
GEO Series GSE114697. Homo sapiens. 48 samples. Type: Other.
Temporal neocortex mesial temporal lobe epilepsy
GEO Series GSE6773. Homo sapiens. 10 samples. Type: Expression profiling by array.
Genome-wide microRNA expression profiles of rat hippocampus in a chronic temporal lobe epilepsy model induced by amygdala stimulation
GEO Series GSE52443. Rattus norvegicus. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Dual-center, dual-platform microRNA profiling identifies plasma biomarkers of adult temporal lobe epilepsy [Beaumont miRNA-seq]
GEO Series GSE114847. Homo sapiens. 3 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Temporal Cortex Control (mesial temporal lobe epilepsy control)
GEO Series GSE6771. Homo sapiens. 10 samples. Type: Expression profiling by array.
Compartment-specific total RNA profile of Hippocampal and Cortical cells from Mesial Temporal Lobe Epilepsy tissue
GEO Series GSE186334. Homo sapiens. 68 samples. Type: Expression profiling by high throughput sequencing.
Glia-specific nuclei isolation and single cell transcriptomics inform astrocyte pathology in human temporal lobe epilepsy
GEO Series GSE140393. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
Hippocampal CA3 Transcriptional Modules Associated with Granule Cell Alterations and Cognitive Impairment in Refractory Mesial Temporal Lobe Epilepsy Patients
GEO Series GSE163296. Homo sapiens. 22 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.