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100 results for “antimicrobial activity”
Fig. 6. ITS2 secondary structures showing significant variations between our isolate A in Funiculosone, a substituted dihydroxanthene-1,9-dione with two of its analogues produced by an endolichenic fungus Talaromyces funiculosus and their antimicrobial activity
Fig. 6. ITS2 secondary structures showing significant variations between our isolate A. Talaromyces sp. (MF927596.1*) and B. T. funiculosus (consensus), incompatible base pairs are highlighted in pale red and yellow colour based on their degrees of incompatibility; * indicating own isolate. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 5 in Funiculosone, a substituted dihydroxanthene-1,9-dione with two of its analogues produced by an endolichenic fungus Talaromyces funiculosus and their antimicrobial activity
Fig. 5. Maximum Parsimony (MP) tree constructed using 88 ITS rDNA (A) and 58 ITS2 sequences (B) of different Talaromyces spp. showing taxonomic placement of our isolate (indicated by an asterisk).
Fig. 3 in Funiculosone, a substituted dihydroxanthene-1,9-dione with two of its analogues produced by an endolichenic fungus Talaromyces funiculosus and their antimicrobial activity
Fig. 3. ECD spectra of funiculosone, 1 (green line) and mangrovamide J, 2 (pink line). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 4 in Funiculosone, a substituted dihydroxanthene-1,9-dione with two of its analogues produced by an endolichenic fungus Talaromyces funiculosus and their antimicrobial activity
Fig. 4. ORTEP view of 2-phase-II showing atomic labeling. Displacement ellipsoids are drawn at the 30% probability level.
Fig. 2 in Funiculosone, a substituted dihydroxanthene-1,9-dione with two of its analogues produced by an endolichenic fungus Talaromyces funiculosus and their antimicrobial activity
Fig. 2. ORTEP view of funiculosone (1) showing atomic labeling. Displacement ellipsoids are drawn at the 30% probability level.
Exploiting the Redox Activity of MIL-100(Fe) Carrier Enables Prolonged Carvacrol Antimicrobial Activity
<p>Relevant data for publication with doi: https://doi.org/10.1021/acsami.1c21555</p>
Computational dataset, scripts and models for 'Lipid shape as a membrane activity modulator of a model antimicrobial peptide'
<p>Analysis scripts and computational models used in the manuscript 'Lipid shape as a membrane activity modulator of a model antimicrobial peptide', by Marcin Makowski, Octávio L. Franco, Nuno C. Santos and Manuel N. Melo.</p>
CalcAMP: A new machine learning model for the accurate pre-diction of antimicrobial activity of peptides
<p>Datasets used for the publication: </p> <p>CalcAMP: A new machine learning model for the accurate prediction of antimicrobial activity of peptides</p>
Fig. 6 in Chemical constituents of Rumex dentatus L. and their antimicrobial and anti-inflammatory activities
Fig. 6. Anti-inflammatory properties of the isolated compounds. (A): Effects of compounds 1–17 and 19 on LPS-induced NO production in RAW264.7 cells at a concentration of 50μM; (B): Effect of compound 9 on the viability of RAW264.7 cells; (C): Effects of compound9 on LPS-induced NO production in RAW264.7 cells at different concentrations.
Fig. 5 in Chemical constituents of Rumex dentatus L. and their antimicrobial and anti-inflammatory activities
Fig. 5. LC‒MS/MS identification. (A): Total ion chromatogram of crude ethanol extract in negative ion mode with numbers of identified compounds; (B): Total ion chromatogram of crude ethanol extract in positive ion mode; (C): HPLC chromatography of crude ethanol extract monitored at 254 nm and names of the two most abundant compounds.
Fig. 2 in Polyketides with antimicrobial activities from Penicillium canescens DJJ-1
Fig. 2. Two possible planar structures of 1 deduced on the basis of 1H–1H COSY and HMBC correlations.
Fig. 3 in Undescribed specialised metabolites from the endophytic fungus Emericella sp. XL029 and their antimicrobial activities
Fig. 3. Key NOESY correlations of compounds 2–7. (Asterisk (*) indicates the partial structures of compounds).
Comparison of leaves and stem Aq. extract of Tridax Procumbens for antimicrobial activity
<p>In present study, aq. extracts of leaves and stem part of Tridax Procumbens were compared for antimicrobial activity. Firstly, all organoleptic and physicochemical properties of leaves and stem powder were evaluated and it shows that drug is pure and having required constituents sufficiently. Aq. extract of leaves powder and stem powder was prepared separately using Soxhlet extraction technique. Both the extracts were evaluated for physiochemical screening using standard procedures. Aq. extract of leaves shows presence of tannis, saponins, anthocyanin, coumarins, alkaloids, proteins, amino acids, diterpenes, phytosterol, cardial glycosides, phlobatannins and flavonoids. Aq. extract of stem shows presence of tannins, coumarins, phenol, cardial glycosides and flavonoids. Both extracts were primarily evaluated for antimicrobial activity against E.coli and S. aureus by selecting dose of 500 mg. Finally, antimicrobial assay was performed for both extracts (500mg) against E.coli and S. aureus by well diffusion method using Amoxicillin and Amikacin as standards respectively. Antimicrobial assay shows that aq. extract of stem part is more effective against S. aureus than E.coli; leaves aq. extract also shows antimicrobial activity against S .aureus and E.coli. From present studies we can conclude that aq. extract of stem and leaves of Tridax Procumbens having antimicrobial activity and stem extract is more effective against S. aureus as compared to leaf extract</p>
Tactic-specific antimicrobial activity suggests a parental care function for accessory glands in a marine toadfish
Open the record for dataset details and reuse information.
Figure 1 from: Hrytsyk RA, Kutsyk RV, Yurchyshyn OI, Struk ОА, Kireev IV, Grytsyk AR (2021) The investigation of antimicrobial and antifungal activity of some Artemisia L. species. Pharmacia 68(1): 93-100. https://doi.org/10.3897/pharmacia.68.e47521
Figure 1 Antimicrobial activity of Artemisia absinthium L., Artemisia vulgaris L., Artemisia abrotanum L. extracts in relation to the test cultures of microorganisms: АEsherichia coli, BStaphylococcus epidermidis, CCandida tropicalis, DAspergillus niger, EEnterococcus faecalis, FStaphylococcus aureus
Scheme from: Matiichuk Y, Gorak Y, Martyak R, Chaban T, Ogurtsov V, Chaban I, Matiychuk V (2021) Synthesis and antimicrobial activity of 4-(5-ARYL-2-FUROYL)morpholines and 4-[(5-ARYL-2-FURYL)carbonothioyl] morpholines. Pharmacia 68(1): 175-179. https://doi.org/10.3897/pharmacia.68.e46942
Scheme Synthesis of 4-(5-aryl-2-furoyl)morpholines and 4-[(5-aryl-2-furyl)carbonothioyl] morpholines.
Data from: A 1,000-year-old antimicrobial remedy with antistaphylococcal activity
Plant-derived compounds and other natural substances are a rich potential source of compounds that kill or attenuate pathogens that are resistant to current antibiotics. Medieval societies used a range of these natural substances to treat conditions clearly recognizable to the modern eye as microbial infections, and there has been much debate over the likely efficacy of these treatments. Our interdisciplinary team, comprising researchers from both sciences and humanities, identified and reconstructed a potential remedy for Staphylococcus aureus infection from a 10th century Anglo-Saxon leechbook. The remedy repeatedly killed established S. aureus biofilms in an in vitro model of soft tissue infection and killed methicillin-resistant S. aureus (MRSA) in a mouse chronic wound model. While the remedy contained several ingredients that are individually known to have some antibacterial activity, full efficacy required the combined action of several ingredients, highlighting the scholarship of premodern doctors and the potential of ancient texts as a source of new antimicrobial agents.
Antimicrobial activity of G. mellonella hemolymph after infection with P. entomophila
<p>This file contains raw data for Fig. 4 DCI (2023) 147, 104749, data are available on request. The work was financed by National Science Centre, project number 2020/37/B/NZ6/00167</p>
Figure 2 from: Vlasov SV, Borysov OV, Severina HI, Vlasov VS, Abu Sharkh AIM, Georgiyants VA (2024) Synthesis, in silico and in vitro antimicrobial activity of N-(benzyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamides. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e110013
Figure 2 Design strategy for target thieno[2,3-d]pyrimidines with benzyl amides fragment as antimicrobial activity.
Figure 4 from: Vlasov SV, Borysov OV, Severina HI, Vlasov VS, Abu Sharkh AIM, Georgiyants VA (2024) Synthesis, in silico and in vitro antimicrobial activity of N-(benzyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamides. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e110013
Figure 4 3D visualization of the compatible conformation the ligand 5.5 (blue molecule) and the reference inhibitor (yellow molecule) (Zhong et al. 2019) in the active site of TrmD P. aeruginosa.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.