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68 results for “bone strength”
The Effects of Dietary Palmitic Acid Triacylglyceride Position on Bone Strength Parameters in Infants
ClinicalTrials.gov study NCT00874068. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Peak vertical jump power predicts radial bone strength better than hand grip strength in healthy individuals
Open the record for dataset details and reuse information.
FIGURE 2 in Body Mass, Bone "Strength Indicator," and Cursorial Potential of Tyrannosaurus rex
FIGURE 2. CT-scan image of the femoral midshaft of MOR 555, showing crushing of the bone, and some of the traverses (white lines) across the femoral cortex used to estimate cortical thickness.
FIGURE 1. Matt B in Body Mass, Bone "Strength Indicator," and Cursorial Potential of Tyrannosaurus rex
FIGURE 1. Matt B. Smith's model restoration of Tyrannosaurus rex, based on MOR 555, as seen in side (A), dorsal (B), and anterior (C) views. Photographs by Bruce Selyem; used by permission of the Museum of the Rockies (photograph numbers PM:39-5, 39-7, 39-10).
FIGURE 4 in Body Mass, Bone "Strength Indicator," and Cursorial Potential of Tyrannosaurus rex
FIGURE 4. Simple model of the vertical force acting on an animal as it hits the ground at the end of a fall. The model can be applied either to the torso of the animal or to its head. The parameters of the model are described in the text.
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength
<p>This data repository contains data in support of "Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength".</p> <p>The following data are included:</p> <ul> <li>Raw genotyping results using the GigaMUGA array for 619 Diversity Outbred mice (.txt files).</li> <li>Genotype probabilities as an Rdata file, calculated using R/qtl2 (pr_basic_cleaned.Rdata).</li> <li>Allele probabilities as an Rdata file, calculated using R/qtl2 (apr_basic_cleaned.Rdata).</li> <li>R/qtl2 cross files for QTL (cross_basic_cleaned.Rdata) and eQTL (cross_eqtl_REDO.Rdata) mapping. Cross files also include covariates (including PEER factors in cross_eqtl_REDO.Rdata).</li> </ul> <p>Supporting sequencing data can be found from the NCBI Gene Expression Omnibus database (GSE152708, GSE152806).</p> <p>For more information, please visit (https://github.com/basel-maher/DO_project).</p> <p>Contact: bma8ne AT virginia DOT edu</p> <p> </p>
Data from: Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth
Administration of sclerostin-neutralizing antibody (Scl-Ab) treatment has been shown to elicit an anabolic bone response in growing and adult mice. Prior work characterized the response of individual mouse strains but did not establish whether the impact of Scl-Ab on whole bone strength would vary across different inbred mouse strains. Herein, we tested the hypothesis that two inbred mouse strains (A/J and C57BL/6J (B6)) will show different whole bone strength outcomes following sclerostin-neutralizing antibody (Scl-Ab) treatment during growth (4.5 – 8.5 weeks of age). Treated B6 femurs showed a significantly greater stiffness (S) (68.8% vs. 46.0%) and maximum load (ML) (84.7% vs. 44.8%) compared to A/J. Although treated A/J and B6 femurs showed greater cortical area (Ct.Ar) similarly relative to their controls (37.7% in A/J and 41.1% in B6), the location of new bone deposition responsible for the greater mass differed between strains and may explain the greater whole bone strength observed in treated B6 mice. A/J femurs showed periosteal expansion and endocortical infilling, while B6 femurs showed periosteal expansion. Post-yield displacement (PYD) was smaller in treated A/J femurs (-61.2%, p < 0.001) resulting in greater brittleness compared to controls; an effect not present in B6 mice. Inter-strain differences in S, ML, and PYD led to divergent changes in work-to-fracture (Work). Work was 27.2% (p = 0.366) lower in treated A/J mice and 66.2% (p < 0.001) greater in treated B6 mice relative to controls. Our data confirmed the anabolic response to Scl-Ab shown by others, and provided evidence suggesting the mechanical benefits of Scl-Ab administration may be modulated by genetic background, with intrinsic growth patterns of these mice guiding the location of new bone deposition. Whether these differential outcomes will persist in adult and elderly mice remains to be determined.
Microarchitecture, Bone Strength and Fracture Risk in Long-term Type 1 Diabetes
ClinicalTrials.gov study NCT03751839. IPD Sharing: NO. Countries: 1. Publications: 0.
Maximal Strength Training Following Hip Fracture Surgery: Impact on Muscle Mass, Balance, Walking Efficiency and Bone Density
ClinicalTrials.gov study NCT03030092. IPD Sharing: NO. Countries: 0. Publications: 2.
Longitudinal Effects of Denosumab on Trabecular Bone Score and Femur Strength Index
ClinicalTrials.gov study NCT02435147. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth
Open the record for dataset details and reuse information.
Systems genetic analysis in Diversity Outbred mice informs human bone mineral density GWAS and identifies Qsox1 as a novel determinant of bone strength
GEO Series GSE152708. Mus musculus. 192 samples. Type: Expression profiling by high throughput sequencing.
FIGURE 3 in Body Mass, Bone "Strength Indicator," and Cursorial Potential of Tyrannosaurus rex
FIGURE 3. How to kill a Tyrannosaurus rex.
Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess.
ClinicalTrials.gov study NCT06344650. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Bone Strength and Physical Activity in Patients With a Recent Clinical Fracture
ClinicalTrials.gov study NCT05138640. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Bone Geometry, Strength, and Biomechanical Changes in Runners With a History of Stress Fractures
ClinicalTrials.gov study NCT00766077. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study on Vertebral Bone Strength by Micro-CT-Like Image
ClinicalTrials.gov study NCT04954417. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of Eccentric Training on Anthropometrics, Physical Fitness and Bone Strength in Overweight Children
ClinicalTrials.gov study NCT04284670. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Vitamin D Supplementation on Strength, Bone Density, and Injury Risk in Collegiate Athletes
ClinicalTrials.gov study NCT03151174. IPD Sharing: NO. Countries: 1. Publications: 0.
Advanced Glycation Endproducts and Bone Material Strength in T2D Treated With Pyridoxamine
ClinicalTrials.gov study NCT03778580. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.