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187
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ShareScore release 0.9.0
Dataset results
187 results for “cannabinoids”
Fig. 5 in Cannabinoid-like meroterpenoids from Peperomia incana
Fig. 5. Effect of compounds 3 and 9 on S. aureus viability.Growth curves of multidrug resistant S. aureus following treatment with compounds 3 (A) and 9 (B).Shortterm analysis of S. aureus viability following exposure to compounds 3 (C) and 9 (D). Each point represents the mean ± SEM of three independent experiments (N = 3).
Fig. 3 in Cannabinoid-like meroterpenoids from Peperomia incana
Fig. 3. Cytotoxic effect of compounds 1–10 from Peperomia incana on A549, MDA-MB-231, HeLa, DU 145, 5637, Hep G2, and MIA PaCa-2 cancer cell lines.Cell viability was analyzed by using an XTT assay for cells treated with different concentrations of tested compounds for 48 h. Doxorubicin was used as a positive control. Data are mean ± SEM of three independent experiments (N = 3).
Fig. 6 in Cannabinoid-like meroterpenoids from Peperomia incana
Fig. 6. Quantitative determination of the formation of multidrug resistant S. aureus biofilms in the presence of the compounds 3 (A) and 9 (B), which were obtained after 24 h of growth.The values represent the mean of three independent experiments ± SEM. * indicates statistical significance (p <0.02) in a two tailed Student's t- test. Compound 3 (MIC = 12.7 μM), compound 9 (MIC = 11.5 μM).
Supplementary File for: Cannabinoid and nicotine exposure during adolescence induces sex-specific effects on anxiety- and reward-related behaviors during adulthood
<p>Raw data from manuscript.</p>
Data from: Cannabinoids disrupt memory encoding by functionally isolating hippocampal CA1 from CA3
Much of the research on cannabinoids (CBs) has focused on their effects at the molecular and synaptic level. However, the effects of CBs on the dynamics of neural circuits remains poorly understood. This study aims to disentangle the effects of CBs on the functional dynamics of the hippocampal Schaffer collateral synapse by using data-driven nonparametric modeling. Multi-unit activity was recorded from rats doing an working memory task in control sessions and under the influence of exogenously administered tetrahydrocannabinol (THC), the primary CB found in marijuana. It was found that THC left firing rate unaltered and only slightly reduced theta oscillations. Multivariate autoregressive models, estimated from spontaneous spiking activity, were then used to describe the dynamical transformation from CA3 to CA1. They revealed that THC served to functionally isolate CA1 from CA3 by reducing feedforward excitation and theta information flow. The functional isolation was compensated by increased feedback excitation within CA1, thus leading to unaltered firing rates. Finally, both of these effects were shown to be correlated with memory impairments in the working memory task. By elucidating the circuit mechanisms of CBs, these results help close the gap in knowledge between the cellular and behavioral effects of CBs.
Simulation dataset for: "The Leu/Val6.51 side chain of cannabinoid receptors regulates the binding mode of the alkyl chain of ∆9-tetrahydrocannabinol"
<p>This dataset contains the prepared systems and the input parameters necessary to guarantee reproducibility of the molecular dynamics simulations of "The Leu/Val6.51 side chain of cannabinoid receptors regulates the binding mode of the alkyl chain of ∆9-tetrahydrocannabinol" work.</p>
Effect of Cannabinoids on Pain in Fabry Disease Patients
ClinicalTrials.gov study NCT04820361. IPD Sharing: NO. Countries: 1. Publications: 3.
Cannabinoids in PLWHIV on Effective ART
ClinicalTrials.gov study NCT03550352. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Fetal Exposure to Cannabinoids: Exposure, Methylation and Neurodevelopmental Effects
ClinicalTrials.gov study NCT04422600. IPD Sharing: Not stated. Countries: 1. Publications: 21.
Cannabinoid Tablets for the Treatment of Pain From Osteoarthritis of the Knee
ClinicalTrials.gov study NCT04992962. IPD Sharing: NO. Countries: 1. Publications: 11.
CANNAbinoids in the Treatment of TICS (CANNA-TICS)
ClinicalTrials.gov study NCT03087201. IPD Sharing: NO. Countries: 1. Publications: 2.
Influence of a Medicinal Cannabinoid Agonist on Responses to Food Images and Food Intake
ClinicalTrials.gov study NCT02310347. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Experimental Medicine in ADHD - Cannabinoids
ClinicalTrials.gov study NCT02249299. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Use of Cannabinoid Patch for Knee Osteoarthritis
ClinicalTrials.gov study NCT04412837. IPD Sharing: NO. Countries: 1. Publications: 9.
Cannabinoids vs. Placebo on Persistent Post-surgical Pain Following TKA: A Pilot RCT
ClinicalTrials.gov study NCT03825965. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Cannabinoids for Pain Management and Neuroprotection From Concussion
ClinicalTrials.gov study NCT06204003. IPD Sharing: NO. Countries: 1. Publications: 1.
Cannabinoids, Neural Synchrony, and Information Processing
ClinicalTrials.gov study NCT00708994. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Neuroprotection by Cannabinoids in Huntington's Disease
ClinicalTrials.gov study NCT01502046. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Cannabinoids Effects on the Pain Modulation System
ClinicalTrials.gov study NCT02560545. IPD Sharing: NO. Countries: 1. Publications: 1.
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
ClinicalTrials.gov study NCT01730781. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.